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百利天恒通过港交所聆讯 旗下Iza-bren是全球首创的双特异性抗体ADC
Zhi Tong Cai Jing· 2025-10-21 23:25
Core Viewpoint - Sichuan Baili Tianheng Pharmaceutical Co., Ltd. is advancing its global strategy in the biopharmaceutical sector, focusing on innovative drug development in oncology, particularly in antibody-drug conjugates (ADC) [1][2] Company Overview - Baili Tianheng is positioned as a comprehensive biopharmaceutical enterprise with leading capabilities in innovative research and development, clinical development, and large-scale production in the ADC/GNC/ARC fields [1] - The company aims to leverage North American and Chinese ecosystems to build a unique core competitiveness and become a multinational corporation (MNC) in the oncology drug market [1] Business Segments - The company operates two main business segments: innovative biopharmaceuticals and generic drugs, including traditional Chinese medicine [1][3] - In the innovative biopharmaceutical segment, the company has developed a pipeline of nine ADC candidates, with approximately 70 clinical studies conducted, including 16 key registration trials in China [2] Key Product Development - Iza-bren is highlighted as the world's first and only EGFR×HER3 bispecific ADC to enter Phase III clinical trials, targeting various epithelial tumors and enhancing tumor-killing activity while reducing off-target toxicity [3][4] - The company has established a global strategic licensing and collaboration agreement with BMS for Iza-bren, which includes joint development and commercialization efforts [4] Financial Performance - The company's revenue for the six months ending June 30 for the years 2022 to 2025 is projected to be approximately 702 million, 560 million, 5.821 billion, and 1.7 billion RMB respectively, with corresponding net profits of -282 million, -780 million, 3.708 billion, and -1.118 billion RMB [4]