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博瑞医药:BGM1812注射液获美国FDA药品临床试验批准
Xin Lang Cai Jing· 2025-09-29 07:43
Core Viewpoint - The company has received FDA approval to initiate Phase I clinical trials for BGM1812 injection, aimed at treating overweight or obesity [1] Group 1: Product Details - BGM1812 injection is a newly designed long-acting Amylin analog with good molecular activity and pharmaceutical stability [1] - Amylin is a satiety hormone composed of 37 amino acids, released by pancreatic beta cells in conjunction with insulin [1] Group 2: Mechanism of Action - The drug activates brain pathways that promote satiety, suppresses appetite, delays gastric emptying, and inhibits glucagon secretion, contributing to its weight loss mechanisms [1]