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The DNA Dilemma: Shaping Bioethical Technologies Together | Andrea Lei | TEDxSHSID Youth
TEDx Talks· 2025-09-19 14:57
I want you guys to all first picture yourselves walking into a salon here. Instead of choosing a new hairstyle, you're choosing new jeans. Would you buy an enhanced memory gene pack that has a coupon for Ivy students.Perhaps a perfect athleticism combo. The case where we can edit our genes easily is a future that we are quickly approaching. And with these emergent technologies, we are facing questions that no challenges before have ever had to answer.Today, I'm not here to assert whether genetic editing is ...
Why cousin marriage is a genetic gamble | Mohammed Jakir Hosen | TEDxCOU
TEDx Talks· 2025-07-29 14:49
[Music] Alam alaikum and very good morning everyone. I'm honored to be here and it is my real privilege to welcome you all to my talk. So today I'm going to talk about one of the most important public health issues that occur everywhere but nobody discussed that much that is the kajim.So think about these two rice. They fall in love and get married. Now they want to extend their family member.Sounds good, right. But problem is what I can say you with they the cousin or genetically related or bloodly related ...
What If We Could Cure Diseases On Demand | Janice Chen | TEDxPaloAltoSalon
TEDx Talks· 2025-07-14 16:51
Gene Editing Technology & Applications - CRISPR technology, inspired by the Nobel Prize-winning discovery of Jennifer Doudna and Emmanuelle Charpentier, functions as a programmable editor to repair genetic defects [5][6] - The technology utilizes a CRISPR protein and guide RNA complex to target and precisely repair problematic DNA sequences [7][8] - Ultra-compact CRISPR systems have been developed to overcome delivery challenges, particularly for tissue-specific delivery via AAV [12][13] - The first FDA-approved CRISPR therapy involves editing blood stem cells outside the body to treat sickle cell disease [14] Delivery Systems - Two primary gene delivery systems exist: Lipid Nanoparticles (LNPs) and Adeno-Associated Viruses (AAVs) [10] - LNPs act as cargo ships, carrying large CRISPR components, primarily docking in the liver [10][11] - AAVs function like drones, delivering smaller CRISPR payloads to specific cell types while minimizing immune responses [11][12] Challenges & Future Directions - Access to cells and tissue types beyond the liver remains a significant challenge for widespread CRISPR deployment [9][16] - Addressing the safety, efficacy, scalability, and accessibility of CRISPR medicines for over 5,000 known genetic diseases is crucial [16] - Advances in AI are accelerating the development of next-generation CRISPR medicines [17] - The industry envisions a future where curing genetic diseases becomes as simple as pairing an ultra-compact CRISPR system with a targeted delivery method [17][18]