Core Insights - The article discusses the advancements in artificial intelligence (AI) and its applications in scientific research, particularly in the fields of chemistry and biology, highlighting the transformative potential of AI in creating innovative solutions and enhancing research efficiency [1][3][4]. Group 1: AI in Scientific Research - AI is being utilized to create verifiable theoretical models and hypotheses, leading to the development of a zero-energy portable water extraction device designed for extreme environments, showcasing the practical applications of AI in solving real-world problems [1]. - A virtual research team composed of seven AI agents was created to optimize the crystallization process of a porous organic framework material, demonstrating the efficiency of AI in conducting numerous experiments and refining conditions rapidly [1][2]. - The RF Diffusion3 model developed by David Baker's team allows for the design of proteins from scratch by generating precise three-dimensional structures based on desired molecular functions, indicating a significant advancement in protein engineering [3]. Group 2: AI and Genetic Research - The integration of CRISPR technology with machine learning enables systematic gene perturbations, facilitating the identification of gene functions and contributing to personalized gene therapy [4]. - The collaboration between AI and CRISPR is positioned as a key tool for constructing causal datasets, which is essential for advancing genetic research [4]. Group 3: Investment in AI Research - Chen Tianqiao, founder of the Tianqiao Brain Science Research Institute, announced a $1 billion investment to support global AI research, emphasizing the importance of AI as an external organ of human evolution [6]. - The expectation is set that the next significant algorithmic breakthrough in intelligence will emerge from personal computing devices rather than centralized data centers, indicating a shift in the landscape of AI development [6].

RT Douglas Yao (@DouglasYaoDY)CRISPR came from yogurt bacteria. GLP-1s came from Gila monster venom. Taq polymerase came from hot spring bacteria.As much as we like to think that progress in biotech is driven by human design, our biggest breakthroughs over the years have all originated from nature. ...

Core Viewpoint - CRISPR technology has made significant advancements in gene editing, but the challenge remains in effectively delivering these tools to the target cells safely and efficiently. A breakthrough from Northwestern University has introduced a new delivery system that enhances the efficiency and accuracy of CRISPR applications in gene therapy [1][3]. Group 1: Current Delivery Methods - Current methods for delivering CRISPR include modified viruses and lipid nanoparticles (LNPs), each with their own limitations. Viruses are efficient but can trigger immune responses, while LNPs are safer but have low delivery efficiency [2]. - Another method involves ex vivo editing, which is complex and costly, making it impractical for most diseases. Thus, there is a need for a safer and more efficient in vivo delivery system [2]. Group 2: New Delivery System - The new system, termed "Lipid Nanoparticle Spherical Nucleic Acids" (LNP-SNA), features a DNA shell that enhances visibility and uptake by cells, significantly improving delivery efficiency [3]. - This innovative delivery vehicle has shown to be over three times more efficient in entering cells compared to traditional lipid nanoparticles, with a significantly lower toxicity profile. The success rate of precise gene editing has increased by over 60% [3]. Group 3: Versatility and Future Applications - The LNP-SNA system is modular, allowing for customization to target specific cell types, such as liver, brain, or cancer cells, thereby enabling precise delivery [4]. - Seven drugs based on similar spherical nucleic acid technology are currently in human clinical trials, with some focusing on cancer treatment. The technology is being promoted by various biotech companies for rapid clinical application [4].

I want you guys to all first picture yourselves walking into a salon here. Instead of choosing a new hairstyle, you're choosing new jeans. Would you buy an enhanced memory gene pack that has a coupon for Ivy students.Perhaps a perfect athleticism combo. The case where we can edit our genes easily is a future that we are quickly approaching. And with these emergent technologies, we are facing questions that no challenges before have ever had to answer.Today, I'm not here to assert whether genetic editing is ...