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创新药品收入超43亿元,复星医药加强双向许可寻新增长
2 1 Shi Ji Jing Ji Bao Dao· 2025-08-27 12:40
Core Insights - Fosun Pharma reported a revenue of 19.514 billion yuan and a net profit of 1.702 billion yuan for the first half of 2025, marking a year-on-year growth of 38.96% in net profit [1] - The company aims to enhance its global operational capabilities and deepen its digital and AI strategy while focusing on innovation and product development [1][2] - The Chinese pharmaceutical industry has become the second largest globally, driven by supportive policies and a strong industry foundation [1][2] Business Performance - The pharmaceutical segment generated 13.901 billion yuan in revenue, with innovative drugs contributing over 4.3 billion yuan, reflecting a 14.26% year-on-year increase [1] - The medical device and diagnostics segment achieved 1.955 billion yuan in revenue, while the healthcare services segment reported 3.592 billion yuan [1] - R&D investment totaled 2.584 billion yuan, with 1.717 billion yuan specifically for R&D expenses, representing 16.51% of pharmaceutical revenue [2] Innovation and Market Strategy - Fosun Pharma is focusing on enhancing the accessibility of innovative drugs through payment innovations and market expansion [3] - The company has included several innovative products in commercial insurance directories, significantly reducing the economic burden on patients [3] - The company is actively exploring the outpatient and self-pay markets to further enhance its commercialization strategy [3] International Expansion - Overseas revenue reached 5.478 billion yuan, accounting for 28.07% of total revenue, with a mature commercialization system established [5] - The company is prioritizing emerging markets such as the Middle East and Southeast Asia for growth opportunities [5][6] - Fosun Pharma has engaged in multiple business development transactions to expand its global market presence [6] Product Development and Licensing - The company is strategically balancing License-in and License-out activities to enhance its product pipeline [6][7] - License-in focuses on filling gaps in technology and product lines, particularly in high-demand areas like Alzheimer's disease [6] - License-out aims to maximize value and patient benefits by leveraging local partners for market entry in regions where the company may face challenges [6][7]
一款国产抗癌药,“少卖”570亿元
Chang Sha Wan Bao· 2025-07-17 16:31
Core Insights - The article discusses the phenomenon of "middlemen profiting" in the innovative drug industry, highlighted by the strategic collaboration between BMS and BNT, which involved a $9 billion deal for the drug BNT327, originally licensed from Chinese company Pumice Biotech [1][2] - The rapid increase in valuations and the perceived undervaluation of Chinese biotech firms are emphasized, with examples illustrating how companies like Pumice and Hengrui have faced challenges in capturing the full value of their innovations [1][2][3] Summary by Sections Strategic Collaborations - BMS and BNT's partnership to develop BNT327 is valued at $9 billion, with Pumice Biotech originally licensing the drug for $55 million [1] - Hengrui Pharmaceuticals licensed its asthma drug SHR-1905 to Aiolos Bio for $25 million upfront, which was later sold to GSK for $10 billion, showcasing the significant markup in valuations [2] Market Dynamics - The article highlights the immature valuation system for innovative drug companies in China and their limited international operational capabilities, leading to unfavorable deals [2][3] - The quality of clinical data and the lack of unique assets hinder Chinese companies' bargaining power in the global market [3] Evolution of BD Transactions - The evolution of business development (BD) transactions in China is outlined, with three phases: exploration (pre-2014), development (2015-2019), and explosion (2020-present) [4][5] - The surge in BD transactions is attributed to the establishment of numerous innovative drug companies post-2010 and regulatory changes that encouraged innovation [5][6] License-in and License-out Trends - License-in transactions dominated initially, allowing companies to mitigate risks and shorten development timelines, but led to inflated prices and market bubbles [6][7] - License-out transactions have recently surpassed License-in, indicating a shift in strategy as companies seek immediate cash flow amid financial pressures [8] New Business Models - The emergence of the NewCo model allows companies to retain longer-term control over their product pipelines while attracting investment, marking a shift from traditional licensing agreements [13][14] - The NewCo model has gained traction among various biotech firms, enabling them to better manage their assets and secure funding [13][15] Future Outlook - The article concludes that while "cheap sales" of assets may continue, Chinese biotech firms are increasingly integrating into the global ecosystem, necessitating a focus on maximizing value within the international value chain [15][16]