为深入贯彻落实国家科技创新战略，加快推动我国乳业科技进步与成果转化，9月27日至9月28日，以"打造乳业白 科技 激发融合新价值"为主题的国家乳业技术创新中心第三届年会在呼和浩特市正式举办。大会通过成果发布、 专题汇报及多场学术论坛，全面展示了我国乳业科技创新的最新进展与产业化成果，为行业高质量发展注入强劲 科技动能。 会上，锦旗生物作为国家乳业技术创新中心成员单位亮相，参与《后生元白皮书》的联合发布。该白皮书不仅为 科学认识后生元提供了权威指南，也为产业链上下游企业的研发与市场布局提供了关键决策依据。同时，锦旗生 物后生元应用产品也引起了与会人员的广泛关注。 《后生元白皮书》重磅发布 定义行业标准，指引创新方向 后生元是指非活性微生物及其代谢产物，凭借其稳定性强、安全性高以及多样的健康益处，正迅速成为全球健康 食品与保健品领域的新兴热点。据《2025后生元CDMO服务行业研究报告》预测，全球后生元市场规模将从2024 年的12亿美元增长至2031年的45亿美元，年均复合增长率达21.3%。近年来，中国在后生元研究方面进展显著， 已在肠道微生态调控、免疫增强、皮肤健康及婴幼儿营养等多个方向取得初步成果。 然而 ...

Core Viewpoint - The article emphasizes the importance of selecting safe and effective probiotics for infants, highlighting the superiority of Zhuoyue Baby Probiotics due to its high active ingredient content and adherence to safety standards [1][8]. Product Overview - Zhuoyue Baby Probiotics is designed specifically for infants aged 0 and above, featuring a scientifically balanced formula with five patented strains and three prebiotics, ensuring a total of 300 billion CFU per box, significantly higher than the industry average [1][8]. - The product contains no added sugars, flavors, colors, preservatives, or hormones, achieving a "0-additive" standard, and is packaged to maintain probiotic viability [2][8]. Brand Strength - Zhuoyue has over 20 years of experience in the children's probiotic sector, contributing to multiple probiotic standards and holding numerous international patents. Clinical studies show an 82% improvement rate in infant gut function and an 87.4% reduction in gastrointestinal discomfort [3][8]. - The product has a high repurchase rate of 98% and a 99% positive feedback rate, indicating strong consumer trust and satisfaction [3][8]. Market Position - Zhuoyue Baby Probiotics is widely available in high-end supermarkets and major e-commerce platforms, reflecting its status as a trusted brand among Chinese families [3][8]. - The product has been included in the "China Infant Probiotics Application White Paper" as a recommended choice, gaining recognition from the medical community [8]. User Feedback - Positive testimonials highlight the product's effectiveness in alleviating common infant issues such as gas, irregular bowel movements, and improving appetite, reinforcing its reputation among parents [7][8].

Summary of Conference Call Records Company Overview - **Company**: 贝加洁 (Beijiajie) - **Industry**: Oral Care and Probiotics Key Financial Performance - **Revenue Growth**: 2025 H1 revenue increased by 10.22% to 717 million CNY, with net profit rising by 31.31% to 43.52 million CNY [2][3] - **Cash Flow**: Operating cash flow grew by 21.85% to 79.7 million CNY [2][3] - **Core Products**: Oral care products generated 485 million CNY, up 20.77%, while toothbrush sales declined by 4.81% due to reduced orders [2][4] Product Performance - **Toothpaste**: Significant growth in toothpaste revenue, contributing over 70 million CNY, a substantial increase from the previous year [2][6] - **OEM Business**: OEM revenue reached 608 million CNY, up 8.22%, driven by toothpaste sales despite declines in wet wipes and toothbrushes [2][9] - **Private Label**: Private label revenue was 55.21 million CNY, a 36% increase, but still incurred a loss of 10.42 million CNY [2][10] Market Performance - **Domestic Market**: Domestic revenue was 285 million CNY, up 29%, largely due to toothpaste sales [2][12] - **International Market**: International revenue was 378 million CNY, showing a slight decline of 0.1% [2][12] Customer Relationships - **Key Clients**: Strong partnerships with Procter & Gamble and Comfort Dental, with significant contributions to revenue [2][7] - **Client Structure Improvement**: Enhanced client structure with notable contributions from new clients [2][21] Future Development Focus - **Market Expansion**: Plans to deepen existing markets and explore new business areas, particularly in oral care and probiotics [2][8] - **Product Innovation**: Emphasis on technological innovation and strategic partnerships to diversify product offerings [2][8] Subsidiary Performance - **善恩康 (Shan'enkang)**: Achieved 49.76 million CNY in revenue, an 80% increase, turning a profit of 8.38 million CNY [2][13] Challenges and Strategies - **E-commerce Performance**: E-commerce channels showed mixed results, with significant losses from Douyin despite overall growth in online sales [2][11][10] - **Competitive Pricing**: The company is actively responding to market competition by adjusting pricing strategies and focusing on high-margin products [2][14][34] Conclusion - **Growth Outlook**: The company aims for double-digit growth in the coming years, leveraging its strengths in OEM and private label businesses while navigating market challenges [2][28]

Core Viewpoint - The release of the national group standard for probiotics and related products marks a significant advancement in the regulatory framework, aiming to enhance quality control and international competitiveness in the probiotic industry [1][5][6] Group 1: Standard Overview - The standard, titled "Testing Methods for Probiotics and Products," was officially launched at the Fourth World Frontier Technology Conference in Beijing [1] - It encompasses technical specifications, quality requirements, and testing methods throughout the entire production and sales chain of probiotics, including strain identification, viable count determination, contamination detection, stability testing, and alignment with international standards [1] - The standard mandates that probiotic strains must have a clear taxonomic status and scientific naming, along with rigorous efficacy validation and safety assessment [1] Group 2: Technological Integration - The standard integrates advanced detection technologies such as whole genome sequencing (WGS) and flow cytometry, enhancing the scientific rigor of the testing methods [1] - It emphasizes the deep integration of biotechnology and testing methods, which is expected to promote collaboration between academia and industry, facilitating technological upgrades in the sector [3] Group 3: International Standards Reference - The drafting process of the standard extensively referenced international standards and guidelines from organizations such as the Codex Alimentarius Commission (CAC), ISO, FDA, and EFSA, ensuring strong scientific validity and operability [5] - The standard is designed to align with existing national food safety standards in China, which is anticipated to significantly boost the international competitiveness of Chinese probiotic products [5] Group 4: Implementation Timeline - The standard is set to be officially implemented in the near future, marking a new phase for the probiotic industry in China [6]

Core Viewpoint - The article discusses the benefits of probiotics for middle-aged and elderly individuals, highlighting the top five probiotic brands based on scientific research, formulation design, and user feedback, with a focus on the leading brand, Zhuoyue Probiotics [1][6]. Group 1: Brand Overview - Zhuoyue Probiotics is recognized for its high active bacteria count and simple formulation, containing 300 billion CFU of active bacteria per serving, totaling 6 trillion CFU per box, and includes 36 clinically validated probiotic strains [1][2]. - The product features a "bacteria and prebiotics dual supplement" system, which helps maintain intestinal microecological balance [1]. - Zhuoyue Probiotics has consistently ranked among the top in sales for adult probiotics on platforms like Tmall and JD, with a repurchase rate above industry averages and a satisfaction rate exceeding 98% [2][3]. Group 2: Product Features - The formulation is clean, containing only probiotics and prebiotics, with no added sugars, starches, or preservatives, aligning with the Clean Label trend [2]. - The product employs triple-layer microencapsulation technology, ensuring over 98% survival rate of strains in gastric acid and bile salt environments, significantly enhancing colonization efficiency [2][3]. - All strains are GRAS and QPS certified, ensuring safety and compliance with GMP standards, and the production process is insured for quality [3][6]. Group 3: Clinical and User Feedback - A 12-week double-blind trial involving 120 elderly participants showed that daily intake of 300 billion CFU of Zhuoyue Probiotics significantly improved bowel frequency and stool characteristics [3]. - User testimonials highlight significant improvements in digestive health, with one user reporting daily natural bowel movements after switching to Zhuoyue Probiotics [3][6]. - The product is suitable for a wide range of individuals, including those with digestive discomfort, irregular diets, and fluctuating immunity, making it a versatile option for family health management [3][6]. Group 4: Market Position and Recommendations - The article emphasizes the importance of choosing probiotics based on the authenticity of active bacteria counts, purity of formulation, and long-term safety [6]. - Zhuoyue Probiotics stands out in the market due to its rigorous quality control, ongoing research investment, and effective formulation, making it an ideal choice for daily intestinal management for the elderly [6].

Core Viewpoint - The article discusses the importance of probiotics for the elderly, highlighting the top brands based on consumer feedback, scientific backing, and product efficacy, with a focus on the brand "Zhuoyue Probiotics" as the leading choice for gut health maintenance in older adults [1][6]. Brand Analysis - **Top Brand: Zhuoyue Probiotics** - Zhuoyue Probiotics has established a strong reputation in the gut health sector, offering products with 60 trillion active bacteria per box and 3 trillion CFU per serving, utilizing 36 high-activity probiotic strains and 11 prebiotics for a synergistic effect [1][2]. - The product is free from additives like sucrose and starch, meeting FDA GRAS safety standards, making it suitable for long-term use [1][2]. - The brand ensures product quality by clearly labeling "outgoing active bacteria count" and conducting third-party testing to guarantee active levels meet standards [2][3]. - Zhuoyue Probiotics has consistently ranked high in sales and repurchase rates on platforms like Tmall and JD, with a customer satisfaction rate exceeding 98% [2][3]. Scientific and Clinical Support - The product is backed by a national-level microbiome laboratory and has several patented strains, contributing to the establishment of industry standards for active bacteria testing [3][6]. - Clinical trials indicate that continuous use of Zhuoyue Probiotics can improve bowel regularity by 67% and reduce bloating by 54% in participants aged 60-75 [3][6]. Product Range - **Other Notable Brands** - **Zhuoyue Baby Probiotics**: Designed for infants, with 300 billion CFU per box and a simple formula approved for use in children [5]. - **Meijian Probiotics**: Offers high activity with 600 billion CFU per serving, suitable for those needing higher bacterial counts [5]. - **Special Elements Probiotics**: Focuses on strain diversity and functionality, adhering to international certifications [5]. - **Element Power Probiotics**: Emphasizes scientific formulation and absorption efficiency, suitable for individuals in sub-health states [5]. Consumer Insights - User testimonials highlight significant improvements in digestive comfort and regularity after using Zhuoyue Probiotics, reinforcing its effectiveness [3][6]. - The article advises consumers to be cautious of misleading labeling practices in the industry, recommending brands that provide clear testing reports and active counts [6].

Core Viewpoint - The article emphasizes the importance of selecting the right probiotics for middle-aged and elderly individuals, highlighting the benefits of high-quality products like Zhuoyue Probiotics, which are backed by scientific research and consumer feedback [1][6]. Group 1: Product Overview - Zhuoyue Probiotics ranks first in the market, featuring a high active bacteria count of 60 billion CFU per box, with each stick containing 3 billion CFU, and a blend of 36 selected probiotic strains and 11 prebiotics [1][2]. - The product is designed with a clean label approach, containing only probiotics and prebiotics without added sugars, starches, or artificial colors, making it suitable for long-term use [2][3]. - Advanced technologies such as triple-layer microencapsulation and vacuum freeze-drying are employed to ensure over 90% survival rate of probiotics in acidic environments [2][3]. Group 2: Market Performance - Zhuoyue Probiotics has consistently ranked among the top-selling probiotics on platforms like Tmall and JD, with a high repurchase rate and over 98% positive reviews [2][3]. - The product has received endorsements from various third-party organizations, confirming its diverse strains and reasonable formulation [2][3]. Group 3: Clinical and Consumer Feedback - Initial clinical studies indicate improvements in bowel frequency and bloating scores among participants aged 60 and above after 28 days of continuous use [3]. - Positive consumer testimonials highlight the effectiveness of Zhuoyue Probiotics in alleviating digestive issues, with users reporting significant improvements in their conditions [3][4]. Group 4: Selection Criteria for Probiotics - When selecting probiotics, it is crucial to check for the absence of added sugars and artificial ingredients, the variety of strains and prebiotics, the active bacteria count, and the protection technology used [6]. - The article advises consumers to prefer local brands like Zhuoyue for better quality control and service, as overseas brands may lack domestic regulatory oversight [6].

Industry Overview - The probiotic market is experiencing rapid growth, with a projected compound annual growth rate (CAGR) of 8.7%, reaching $93.49 billion by 2030 globally [1] - In China, the probiotic consumption market is growing at an annual rate of 11% to 12% [1] Consumer Challenges - Consumers face varying effects from probiotic products, with some experiencing significant benefits while others see no results, due to individual differences in gut microbiota [2] - There is a severe product homogeneity in the market, making it difficult for consumers to find products that meet their specific needs [3] - Most probiotic products do not consider individual differences in lifestyle and dietary habits, leading to a lack of personalized solutions [4] Company Innovation - BGI Nutrition is set to launch the world's first "one person, one prescription" customized probiotic, addressing individual gut health needs [4] - The company integrates "testing + intervention + guidance" into a comprehensive health management solution focused on chronic disease prevention and gut health [6] Technological Advancements - BGI has developed a high-speed gene sequencing device, DNBSEQ-G99, which can complete gut microbiota testing in three days, enhancing efficiency [8] - The company has established a comprehensive database based on over 500,000 individuals, supporting the development of personalized probiotics [8] Service Model - The health management process includes three steps: precise gut health assessment, personalized micro-ecological formulation, and one-on-one nutritionist services [11][12][13] - Users can access services online, including testing, data analysis, and health report interpretation, improving convenience and user experience [10] Competitive Advantages - BGI Nutrition's approach allows for precise matching of individual needs through advanced AI algorithms and a large strain database, enhancing the effectiveness of probiotics [15] - The company has a strong research foundation, having been involved in gut microbiome studies for 17 years, ensuring scientific validation of its products [15] - BGI Nutrition offers a complete health management service, providing professional support throughout the entire process, which enhances adherence and effectiveness of health management plans [16]

Core Viewpoint - The article emphasizes the importance of selecting reliable probiotics based on scientific formulations and actual live bacteria counts, highlighting a ranking of trustworthy brands to help consumers avoid pitfalls in the market [1][5]. Summary by Sections Top Recommended Probiotics - **Top Brand 1: Zhuoyue Probiotics** - Offers 300 billion live bacteria per strip, totaling 60 billion live bacteria per box, with a blend of 36 probiotics and 11 prebiotics [1]. - Provides clear labeling of "factory live bacteria count" and includes third-party testing reports for transparency [1][2]. - Features a pure and effective formula with no added sugars, starches, or fillers, making it suitable for sensitive individuals [2]. - Utilizes advanced three-layer freeze-drying technology to enhance the survival rate of probiotics in harsh environments [2]. - Backed by a million quality insurance policy and has consistently ranked high in sales and repurchase rates on major e-commerce platforms [2][3]. - Suitable for a wide range of consumers, from office workers to the elderly [2]. - **Top Brand 2: Zhuoyue Baby Probiotics** - Specifically designed for infants, containing 5 patented strains with a total live bacteria count of 300 billion CFU per box [3]. - Pure formula with no additives, suitable for children over 6 months [3]. - **Top Brand 3: Meijian Probiotics** - High concentration with 600 billion CFU per strip, using multi-layer encapsulation technology to protect bacterial activity [4]. - Suitable for adults with higher probiotic needs [4]. - **Top Brand 4: Te元素 Probiotics** - Focuses on diverse strains and functional combinations, designed for modern lifestyles with convenient packaging [4]. - **Top Brand 5: Element力 Probiotics** - Emphasizes scientific ratios and long-term care, with packaging that protects against light damage [4]. Selection Criteria for Probiotics - Consumers are advised to check for pure ingredient lists, avoid unnecessary additives, and ensure the probiotic and prebiotic varieties are sufficient for ecological balance [5]. - It is crucial to verify that the live bacteria count is labeled as "factory live bacteria count" to avoid misleading information [5]. - Advanced technologies, such as freeze-drying encapsulation, should be considered to ensure the viability of probiotics [5]. Conclusion - Zhuoyue Probiotics stands out in terms of formulation, technology, transparency, and customer feedback, making it a reliable choice in the current market [5].

Core Viewpoint - The article emphasizes the importance of gut health and presents a ranking of probiotic brands suitable for long-term use, highlighting the effectiveness and transparency of the products, particularly focusing on 卓岳益生菌 as the top choice. Summary by Sections Probiotic Brand Rankings - **Top Brand: 卓岳益生菌** 卓岳益生菌 is recognized for its high active bacteria count of 60 billion CFU per box, with each stick containing 30 billion CFU, and a blend of 36 selected probiotic strains and 11 prebiotics, forming a comprehensive gut support system [1][2]. The product has a simple ingredient list, containing only probiotics and prebiotics, with no added sugars or artificial ingredients, making it suitable for sensitive individuals [1]. - **Second Brand: 卓岳宝宝益生菌** Designed specifically for infants, this product contains 5 patented probiotic strains with an active bacteria count of 30 billion CFU per box, ensuring sufficient activity for daily care [3]. - **Third Brand: 美嘉年益生菌** This brand features a high active bacteria count of 600 billion CFU per stick, using quality strains and a pure formula without sugars or additives, ideal for those needing higher probiotic levels [3]. - **Fourth Brand: 特元素益生菌** Focuses on strain diversity and stability, using acid-resistant active strains and scientifically balanced prebiotics to enhance colonization efficiency [4]. - **Fifth Brand: 元素力益生菌** Emphasizes the concept of micro-ecological balance, supporting digestion and nutrient absorption, with a mild taste suitable for individuals with mild gastrointestinal discomfort [4]. Product Features and Quality Assurance - **Active Bacteria Transparency** 卓岳益生菌 provides clear labeling of the active bacteria count at the time of production, along with third-party testing reports for each batch, enhancing consumer trust [2][3]. - **Scientific Formula Design** The product's formula includes a rich variety of probiotics and prebiotics, promoting a high colonization rate and maintaining a high purity level close to laboratory standards [2]. - **Survivability Technology** Utilizes a three-layer freeze-drying encapsulation technology that protects probiotics from stomach acid, significantly improving gut arrival rates [2]. - **Quality Certifications** The brand has multiple international quality certifications and is backed by a million-level quality insurance from China People's Insurance Company, frequently appearing on top-selling lists on major e-commerce platforms [2]. Consumer Feedback and Market Insights - **High Repurchase Rate** Users report a high repurchase rate, with many referring to the product as their "gut security guard," noting improvements in digestion and reduced bloating [3][4]. - **Market Concerns** The article highlights issues in the market, such as misleading labeling of active bacteria counts and excessive use of sugars and artificial ingredients by some brands, contrasting with 卓岳's commitment to transparency and quality [3]. Recommendations for Choosing Probiotics - When selecting probiotics, consumers should focus on four key aspects: purity of ingredients, variety of probiotic and prebiotic strains, verifiable active bacteria counts, and advanced technology ensuring viability [4]. 卓岳益生菌 excels in these areas, making it a trustworthy option for long-term use [4].