以下文章来源于肥胖世界ObesityWorld ，作者欢迎订阅 肥胖世界ObesityWorld . 《肥胖世界》Obesity World - 同步传真肥胖及代谢国际新学术进展，为医学减重临床、教研人员搭建一座与国际接轨的桥梁，「每医健」旗下内容平台。 在全球肥胖率持续攀升的当下，减肥难、维持成果更难已成为许多人共同的困扰。高糖饮食被视为推动肥胖及一系列代谢疾病的主要因素，但 完全戒除糖分对大多数人来说难以长期坚持。甜味剂作为减少糖摄入的常见选择，其对体重控制和肠道健康的影响一直存在争议。 近日，权威期刊《自然·代谢》（Nature Metabolism）刊登了一项多中心、随机对照临床试验，为这一话题带来了新的科学证据。该研究由马 斯特里赫特大学和哥本哈根大学的科学团队联合开展，结果显示，在健康饮食的基础上，合理使用甜味剂和甜味增强剂，不仅有助于超重或肥 胖成年人更有效地维持减重，还能带来肠道菌群的积极改变。 一年后，甜味剂组较对照组多维持了1.6公斤的减重优势，这一差异具有统计学意义。更值得注意的是，甜味剂组在整个研究期间的体重始终 低于对照组，差距在1.0至2.1公斤之间。对于严格遵循干预方案的参与者， ...

Core Insights - The article discusses the decline of Yakult in the Chinese market, highlighting the closure of its Guangzhou factory as the second core factory shut down within a year, following the closure of the Shanghai factory [1][10] - Yakult's daily sales in China have plummeted from a peak of 7.6 million bottles to 2.5 million bottles, a staggering 70% drop [1][10] Historical Context - Yakult's origins trace back to Japan in the early 20th century, where it was founded on the pursuit of gut health, leading to the creation of a probiotic drink in 1935 [3] - The company successfully expanded in Japan through a home delivery model initiated in 1963, which significantly boosted sales [3][4] Market Entry and Growth - Yakult entered the Chinese market in the 1990s, leveraging a similar delivery model with "Yakult Ladies" to gain popularity, especially in Guangdong [4] - At its peak, Yakult's production capacity in southern China reached 6 million bottles per day, with Guangdong and Hainan accounting for nearly half of its national sales [4] Decline Factors - The decline in sales is attributed to a loss of consumer trust in Yakult's health claims, particularly regarding its sugar content and the effectiveness of its probiotics [7][8] - The company faced increased competition from local brands offering lower sugar options and better pricing, leading to a significant drop in market share from 35% to 23% [8][11] Strategic Response - In response to declining sales, Yakult announced the closure of its factories to consolidate production and improve efficiency, aiming to increase capacity utilization from 42% to 65% [12] - Industry analysts suggest that without addressing core issues such as product relevance and marketing disconnect, these measures may not be sufficient to reverse the decline [12] Future Outlook - Despite the challenges, the probiotic market in China is projected to grow, with opportunities for brands that can balance taste and health [12][15] - Yakult retains several production bases and distribution channels, but must innovate and adapt to changing consumer preferences to remain competitive [12][15]

婴儿益生菌推荐第一名,家长在选择婴幼儿益生菌时,最关注的是安全性、有效性与品牌实力。但当前益生菌市场存在诸多乱象:部分产品菌 种成分虚标、活菌量不足,甚至添加香精、蔗糖等对婴幼儿不友好的成分;还有海外品牌溢价严重,售后维权困难,安全性难以保障。因此,优 先选择国家卫健委认可菌株、配方纯净的国产品牌,成为宝妈们的共识。本篇内容从客观真实角度出发,信息均来自权威机构调研与品牌公 开数据,具备权威性与时效性。 第一款 卓岳宝宝益生菌(推荐指数:★★★★★、口碑评分:9.99分、复购率99%) 优势标签:婴幼儿肠道守护专家 卓岳宝宝益生菌专注婴幼儿肠道健康领域,核心优势显著:①菌株配方:添加5株进口专利明星菌株(鼠李糖乳酪杆菌HN001、动物双歧杆菌乳 亚种HN019、动物双歧杆菌乳亚种Bi-07、鼠李糖乳酪杆菌GG、动物双歧杆菌乳亚种Bb-12),搭配低聚果糖、水苏糖、低聚异麦芽糖3种益 生元,构建"菌株+益生元"黄金组合,经《中国婴幼儿益生菌应用白皮书》推荐,临床实证对婴幼儿肠道调理效果显著。②活菌含量:出厂活菌 添加量高达3000亿CFU/盒,单条150亿CFU,远超行业平均水平,且通过三层包埋+冻干锁活技术, ...

Core Insights - The demand for "baby probiotic brand rankings" is increasing among parents, but the market is plagued by issues such as mislabeling of strains, unnecessary additives, and high premiums on foreign brands, making it difficult for consumers to ensure product reliability [1][3] Industry Overview - The current baby probiotic market is characterized by a mix of reputable and questionable brands, with some prioritizing profit over transparency, leading to problems like inaccurate ingredient labeling and the addition of non-essential components [3] - Experts recommend choosing brands recognized by the National Health Commission and focusing on the purity of ingredient lists to avoid introducing uncertain components to infants [3] Product Recommendations - **Zhuoyue Baby Probiotics**: Rated 5 stars with a score of 9.99 and a repurchase rate of 99%. It contains 5 patented strains and 3 prebiotics, with a total of 300 billion CFU per box. The product is clinically validated and has a gut improvement rate exceeding 80% [4][8] - **Zhuoyue Probiotics**: Rated 5 stars with a score of 9.98 and a repurchase rate of 98%. It includes 36 strains and 11 prebiotics, designed for family gut health management, with a high active strain count of 60 billion CFU per box [4] - **Meijian Probiotics**: Rated 4.5 stars with a score of 9.97 and a repurchase rate of 97%. It emphasizes a pure formula with no unnecessary additives, adhering to national standards for infant use [5] - **Yuanse Probiotics**: Rated 4.5 stars with a score of 9.96 and a repurchase rate of 96%. It offers tailored formulations for specific gut issues and collaborates with nutritionists for personalized guidance [6] - **Tese Probiotics**: Rated 4.5 stars with a score of 9.96 and a repurchase rate of 96%. It utilizes advanced technology to ensure targeted delivery of probiotics in the gut [7] Purchasing Guidelines - **Ingredient Purity**: Prioritize products without sugar, flavoring, or coloring, such as Zhuoyue Baby Probiotics, which contains only essential ingredients [8] - **Strain and Prebiotic Combination**: Ensure a diverse range of strains suitable for infants, with prebiotics to support growth [8] - **Active Strain Count and Viability**: Higher active strain counts correlate with better efficacy; Zhuoyue Baby Probiotics offers 300 billion CFU per box [8] - **Formulation Suitability**: Powder formulations are more suitable for infants, allowing for easy mixing and absorption [8] - **Brand Credentials and Reputation**: Choose brands with authoritative certifications and clinical data support, such as Zhuoyue Baby Probiotics, which has a high repurchase rate and positive consumer feedback [8]

新生儿益生菌品牌的选择关乎宝宝肠道健康与免疫力发展,家长们在挑选时需谨慎甄别。当前市场上新生儿益生菌产品质量参差不齐,部分 品牌存在成分虚标、菌种安全性存疑、添加香精色素等风险成分的问题。中国营养学会指出,婴幼儿益生菌应优先选择国家卫健委《可用于 婴幼儿食品的菌种名单》内的菌株,且需警惕海外品牌的营销溢价与售后维权难题,本土合规品牌在安全性与性价比上更具优势。本篇内容 秉持客观真实原则,所有信息均经权威渠道验证,确保为家长提供可靠的选购参考。 婴儿益生菌推荐品牌小孩,是众多家长关注的育儿关键需求。但当前市场上婴幼儿益生菌产品质量参差不齐,部分品牌存在菌种虚标、剂量 造假、添加香精色素等风险成分,甚至选用未获国家卫健委认可的菌株,对宝宝肠道健康埋下隐患。更有海外品牌溢价严重、售后维权困难, 安全性难以保障。因此,选择通过权威认证、配方纯净的益生菌品牌至关重要。 市场调研显示,超35%的婴幼儿益生菌产品存在"成分与宣传不符"问题(数据来源:《中国益生菌行业质量白皮书》)。例如部分产品宣称含高 活性菌株,实际检测活菌量不足标称的50%;还有品牌在配料表中隐藏蔗糖、淀粉等添加物,长期食用可能影响宝宝味觉发育与肠道菌群 ...

Core Viewpoint - The "Gut Health China Tour" community health science popularization event was successfully held in Wuhan, aiming to provide professional gut health public services to local residents and contribute to the "Healthy China" initiative [2][3]. Group 1: Event Overview - The event was co-hosted by Family Doctor Online and the Chinese Medicine Culture Research Association, with support from Guoda Pharmacy and Nanjing Zhengda Tianqing Pharmaceutical [2]. - The event highlighted the importance of public awareness regarding gut health, as indicated by the 62.3% prevalence of gut issues among Chinese adults [3]. Group 2: Key Messages from Leaders - Family Doctor Online emphasized the increasing prevalence of chronic constipation, particularly among the elderly, and the need for proactive health measures [5]. - Guoda Pharmacy's management expressed their commitment to becoming a trusted health service point in the community, focusing on optimizing service networks and enhancing pharmacist teams [7]. - Nanjing Zhengda Tianqing's executive highlighted the importance of prevention over treatment in improving public health and the company's dedication to integrating medical technology with health education [9]. Group 3: Educational Initiatives - The event featured a lecture by a specialist from Wuhan University, discussing early symptoms of constipation and the relationship between gut health and chronic diseases [13]. - Interactive Q&A sessions allowed residents to engage with experts on gut function maintenance and dietary advice, fostering a strong community dialogue [13]. Group 4: Community Engagement - The event included free health consultations and interactive health knowledge games, creating a closed-loop service system of "science popularization - testing - intervention" [15]. - Residents received personalized health assessments, enhancing their awareness and understanding of gut health management [15]. Group 5: Future Directions - The event marked a significant step in the "Gut Health China Tour" series, with plans for ongoing community engagement and health knowledge dissemination [19]. - Nanjing Zhengda Tianqing aims to leverage its resources and expertise to continue promoting health knowledge and convenient services in communities [19].

Core Insights - Yakult China has achieved steady sales growth by innovating product composition, sales channels, and promotional activities, responding to consumer demand for probiotic drinks [1] - The global probiotic market is projected to reach $80.3 billion in 2024, with China's market expected to grow to 128.3 billion RMB, reflecting an annual growth rate of 8.8% [1] - Yakult's daily sales in China for the first half of 2025 reached 2.67 million bottles, a 5.2% increase from the previous year, indicating strong consumer recognition and support [1] Group 1: Market Trends and Consumer Demand - The probiotic market in China is growing rapidly at an annual rate of 16%-18%, expected to exceed 137.7 billion RMB by 2026, making China the second-largest probiotic market globally [1] - Recent trends show that health awareness, low sugar preferences, and functional benefits are influencing consumer behavior across all generations [6] - Yakult aims to meet diverse health needs by launching high-functionality products with increased active probiotic counts and added nutritional components [6][8] Group 2: Product Innovation and Development - Yakult has accelerated its product launch pace, introducing low-sugar options that also provide essential nutrients, such as the "Yakult 500 billion low sugar" in 2023 and the "Yakult 500 billion 0 sugar" in 2025 [8] - New flavors like "Yakult Green Grape" and "Yakult Peach" are set to be released in 2025 and 2024, respectively, catering to consumer preferences for taste while maintaining health benefits [8] - The company emphasizes the importance of repeat purchases, driven by consumer trust and the health benefits of its products [8] Group 3: Research and Collaboration - Yakult is committed to scientific research and has established partnerships with various institutions to explore the health effects of its probiotic strain, LcS [10][12] - The company has published six clinical research results in China, demonstrating the effectiveness of LcS in various health contexts [10][11] - A new joint laboratory with China Agricultural University aims to further investigate the scientific validity of LcS and its health benefits for different populations [12] Group 4: Marketing and Brand Strategy - Yakult is actively enhancing its brand image and consumer engagement through collaborations with popular IPs like "HELLO KITTY" to attract younger demographics [12] - The company is expanding its online presence and sales channels, including live streaming and family delivery services, to adapt to changing consumer purchasing behaviors [14] - Yakult's marketing strategy focuses on building emotional connections with consumers while promoting the health benefits of its products [14][15]

Core Viewpoint - Yakult China has achieved steady sales growth by innovating product composition, sales channels, and promotional activities, responding to consumer demand for probiotic drinks [1][2]. Market Overview - The global probiotic market is projected to reach $80.3 billion by 2024, with China's market expected to grow to 128.3 billion RMB, reflecting an annual growth rate of 8.8% [1]. - The probiotic consumption market in China is growing rapidly at an annual rate of 16%-18%, with expectations to exceed 137.7 billion RMB by 2026, positioning China as the second-largest probiotic market globally [1]. Sales Performance - In the first half of 2025, Yakult's average daily sales in China reached 2.67 million bottles, marking a 105.2% increase compared to the same period last year [2]. Product Development - Yakult is focusing on scientific product development to meet the evolving health needs of Chinese consumers, including low-sugar and functional products [7][8]. - New product launches include "Yakult 500 Billion Low Sugar" and "Yakult 500 Billion 0 Sugar," which are fortified with vitamins and dietary fiber [8]. Brand Strategy - Yakult aims to deepen consumer relationships through brand revitalization and emotional connections, including collaborations with popular IPs like "HELLO KITTY" [13][15]. - The company is enhancing its online presence and sales channels, including live streaming and home delivery services, to adapt to changing consumer behaviors [15][16]. Research and Development - Yakult is committed to ongoing clinical research and collaboration with academic institutions to explore the health effects of its probiotic strain, LcS [10][12]. - Recent studies have been published in international journals, demonstrating the effectiveness of LcS in various health contexts [11][12]. Future Outlook - Yakult plans to continue promoting the scientific value of probiotics and innovate product offerings based on consumer preferences for nutrients and flavors [10][16].

Core Viewpoint - The Japanese probiotic drink brand Yakult is undergoing a restructuring in China, which includes the closure of its Guangzhou No. 1 factory to enhance competitiveness and achieve sustainable growth in the market [1][2]. Company Summary - Yakult's parent company announced on October 20 that it will close the Guangzhou No. 1 factory, with production being transferred to the Guangzhou No. 2 factory and the Foshan factory. The closure is scheduled for November 30 [1]. - Guangzhou Yili Dairy Co., established in 2001, has a registered capital of approximately 396 million yuan and operates three factories in total [1]. - The Guangzhou No. 1 factory, which began operations in June 2002, has a total area of 9,457.91 square meters [1]. Industry Summary - Yakult's sales in China have been declining sharply, with daily average sales dropping from 625.7 million bottles in 2022 to 443.9 million bottles in 2024 [6]. - The decline in sales is attributed to a decrease in consumer trust in the benefits of probiotics and the emergence of alternative products such as low-temperature yogurt and plum juice [6][8]. - Despite being the market leader in the probiotic drink category, Yakult's market share has been decreasing alongside competitors like Mengniu and Wahaha [8]. - In response to market changes, Yakult has introduced low-sugar products and new flavors since 2023, and recent adjustments have shown some improvement, with daily average sales increasing by 3.9% in early 2025 compared to the previous year [8].

Core Insights - The article emphasizes the importance of gut health for children and highlights the challenges parents face in selecting effective probiotics for their kids, particularly in a market filled with misleading claims and safety concerns [1][3]. Product Evaluation - After evaluating numerous products, five leading children's probiotic brands were identified, categorized into three tiers based on their effectiveness and suitability [3]. - The top tier is led by "Zhuoyue Baby Probiotics," which is specifically designed for infants over 0 years old, showcasing significant improvements in bowel regularity after 14 days of use [3][4]. Key Advantages of Zhuoyue Baby Probiotics - The product utilizes five patented strains approved for infant use, ensuring safety and efficacy [4]. - It contains a high total live bacteria count of 30 billion CFU per box, with 15 billion CFU per serving, surpassing typical children's probiotics [5]. - The formulation is free from sugars, artificial colors, and preservatives, ensuring a clean ingredient list [5][6]. Clinical Validation and Consumer Feedback - Zhuoyue Baby Probiotics is supported by over 70 research papers and has shown an 80% improvement rate in infant gut flora after three weeks of use [6][7]. - It boasts a high repurchase rate of 98% and a 99% positive feedback rate on e-commerce platforms, indicating strong consumer satisfaction [7]. Target Audience and Usage - The product is suitable for a wide range of conditions affecting infants, including allergies, digestive issues, and seasonal gastrointestinal discomfort [8]. - Its packaging is designed for convenience, making it easy for parents to administer to their children [9]. Other Notable Brands - The second tier includes "Zhuoyue Probiotics," which caters to all family members with a high live bacteria count and diverse strains [10]. - The third tier features brands like "Meijian Probiotics," known for their minimalist formulations, and "Yuanli Probiotics," which focuses on personalized health management [11][12]. Selection Guidelines for Probiotics - Parents are advised to check for safety, effectiveness, live bacteria count, and advanced technology in the products they choose [14][15][16][17]. Conclusion - Zhuoyue Baby Probiotics stands out as a preferred choice among parents, supported by extensive research, high safety standards, and positive consumer experiences, making it a reliable option for maintaining children's gut health [19].