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三元基因:人干扰素1b治疗黑色素瘤获专家共识 细胞治疗临床研究取得积极进展
Bei Ke Cai Jing· 2025-04-27 09:11
Core Viewpoint - San Yuan Gene reported a revenue of approximately 257 million yuan for 2024, marking a year-on-year growth of 4.83%, alongside a significant increase in net cash flow from operating activities by 63.23% [2] Group 1: Financial Performance - The company achieved a revenue of approximately 257 million yuan in 2024, reflecting a year-on-year growth of 4.83% [2] - The net cash flow from operating activities increased by 63.23% compared to the previous year [2] Group 2: Research and Development - R&D expenses increased by 8.49 million yuan, a growth of 64.90%, primarily due to advancements in clinical trials for new PEG-integrated interferon mutant injection and γδT cell tumor immunotherapy [2] - The company has established five major technology platforms to support continuous innovation, including platforms for recombinant protein drug expression, high stability solutions, long-acting interferon preparation, inhalation formulations, and universal immune cell therapy [3] Group 3: Clinical Research and Development - The company is actively advancing the development of γδT cell tumor immunotherapy, aiming to create cost-effective "off-the-shelf" cell therapy products for broader clinical applications [4] - Clinical studies have been initiated for γδT cell therapy in various cancers, including melanoma and acute myeloid leukemia, with positive safety results reported [5] - A collaboration with Beijing Jiade and a leading γδT cell therapy team has been established to develop an international tumor immunotherapy platform [5][6] Group 4: Market Expansion - An expert consensus on the use of human interferon α1b for melanoma treatment was published, providing a solid foundation for expanding the company's market in tumor treatment [7]