Group 1: Optical Tweezers (OT) - Optical tweezers, invented by Arthur Ashkin in 1986, utilize laser light to manipulate microscopic objects without physical contact, minimizing damage to biological samples [4][5] - The technology has evolved over 40 years, expanding its application from micron-sized spheres to atomic and nanoscale objects, and is now a key tool in cell manipulation and biophysical research [4][5] - Major applications include single-molecule biology, assisted reproduction, and capturing rare cells, with companies like Changguang Chenying and Catcher representing the domestic market [5][10] Group 2: Optical Electric Tweezers (OET) - Optical electric tweezers, inspired by optical tweezers, were developed in 2005 and commercialized by Berkeley Lights in 2011, later acquired by Bruker in 2023 [2][17] - OET technology generates non-uniform electric fields to manipulate particles, allowing for high-throughput applications in cell sorting, analysis, and drug delivery [15][19] - The technology faces high barriers to entry due to complex know-how and high R&D costs, with few companies successfully commercializing it [17][18] Group 3: Industry Trends and Future Prospects - The integration of OET with microfluidics is transforming biopharmaceutical research, enabling high-throughput screening and antibody development [19][20] - Future trends include the automation of processes through AI, the introduction of new materials for better biocompatibility, and modular integration for compact systems [20] - Companies like Micronano Power and Catcher are leading innovations in the field, with products that enhance precision and efficiency in cell manipulation [23][12]

Core Viewpoint - The successful bid of CaiKe Bio for the Tsinghua University single-cell optical guiding system project signifies a substantial breakthrough in the recognition of high-end life science instruments in leading research institutions in China, reflecting the growing acceptance of domestic scientific instruments [1][3]. Group 1: Project Details - The project number for the Tsinghua University single-cell optical guiding system procurement is 清采招第20240297号 [3]. - The total budget for the project was 23.92 million yuan, with CaiKe Bio winning the bid at a transaction amount of 17.90 million yuan [1][2]. - The supplier, YuGuo Biotechnology (Beijing) Co., Ltd., is located in Beijing Economic and Technological Development Zone [3]. Group 2: Product Information - The product being supplied is a single-cell optical guiding system, with the brand being CaiKe (Suzhou) Biotechnology Co., Ltd. [3]. - The model includes LyKIPP and a four-chip high-throughput single-cell optical guiding system [3]. - The quantity of the product is one set, with a unit price of 17.90 million yuan [3].