Core Viewpoint - WuXi AppTec has reported a strong performance in Q3 2025, with revenue and net profit both increasing, while also announcing a strategic focus on its CRDMO (Contract Research, Development, and Manufacturing) core business by divesting its clinical operations [1][2][5]. Financial Performance - For the first three quarters of 2025, the company achieved revenue of 32.86 billion yuan, a year-on-year increase of 18.6%, and a non-GAAP net profit attributable to shareholders of 9.52 billion yuan, up 42.5% [2][3]. - In Q3 alone, revenue reached 12.06 billion yuan, reflecting a 15.3% year-on-year growth, while non-GAAP net profit surged by 73.8% to 3.94 billion yuan [2][3]. Business Segments - The chemical business was the largest contributor to revenue, generating 25.98 billion yuan, a 29.3% increase year-on-year, driven by strong performance in small molecule drug discovery and development [4][5]. - The company reported a backlog of orders in its continuing operations amounting to 59.88 billion yuan, a 41.2% increase year-on-year, indicating robust demand [4]. Strategic Moves - WuXi AppTec announced the sale of its clinical research subsidiaries, Shanghai Kande Hongyi Medical Research Co., Ltd. and Shanghai WuXi Jishi Pharmaceutical Technology Co., Ltd., to Hillhouse Capital for a base price of 2.8 billion yuan [7][10]. - The divestiture is part of the company's strategy to concentrate on its CRDMO business model, which is expected to enhance its global capabilities and operational efficiency [12]. Operational Efficiency - The company has focused on optimizing production processes and improving operational efficiency, which has contributed to increased profitability and capacity utilization [5][6].

Core Viewpoint - The company, WuXi AppTec, reported strong financial performance for the first three quarters of 2025, with significant growth in various business segments, particularly in the CRDMO (Contract Research, Development, and Manufacturing) model, and announced a strategic asset sale to focus on core operations [1][26][29]. Financial Performance - As of September 30, 2025, the company had a backlog of orders amounting to RMB 59.88 billion, representing a year-on-year increase of 41.2% [5]. - The total revenue for the first three quarters of 2025 reached RMB 32.45 billion, with a year-on-year growth of 18.6% [5]. - Revenue from continuous operations grew by 22.5%, with chemical business revenue at RMB 25.98 billion, up 29.3% year-on-year [5][6]. Business Segments - The small molecule drug discovery segment delivered over 430,000 new compounds in the past year, with 250 molecules transitioning from research to development in the first three quarters of 2025 [6]. - The small molecule development and manufacturing (D&M) segment reported revenue of RMB 14.24 billion, a 14.1% increase year-on-year, with a total of 3,430 molecules in the pipeline [6]. - The TIDES (oligonucleotide and peptide) business saw revenue of RMB 7.84 billion, a remarkable growth of 121.1% year-on-year, with a 17.1% increase in backlog orders [7]. Strategic Decisions - The company announced the sale of 100% equity in two subsidiaries for a base price of RMB 2.8 billion to streamline operations and focus on its CRDMO business model [26][29]. - The board of directors approved the asset sale on October 24, 2025, with a unanimous vote, indicating strong internal support for the strategic shift [22][30]. Market Position - WuXi AppTec maintains a strong reputation in the global pharmaceutical R&D industry, adhering to the highest international quality standards and continuously optimizing its integrated CRDMO service model [2][3]. - The company has established a robust client base across various regions, including the US, Europe, and China, with significant revenue contributions from these markets [5].

Core Insights - WuXi AppTec (603259.SH) reported a revenue of RMB 32.857 billion for the first three quarters of 2025, representing a year-on-year growth of 18.61% [1] - The net profit attributable to shareholders reached RMB 12.076 billion, showing a significant increase of 84.84% year-on-year [1] - The net profit after deducting non-recurring gains and losses was RMB 9.522 billion, up by 42.51% year-on-year [1] Group 1: Chemical Business - The chemical business generated revenue of RMB 25.98 billion, reflecting a year-on-year growth of 29.3% [1] - The small molecule drug discovery ("R") business has successfully synthesized and delivered over 430,000 new compounds to clients in the past twelve months [1] - In the first three quarters of 2025, the company converted 250 molecules from research to development [1] Group 2: Small Molecule Development and Manufacturing (D&M) - The small molecule D&M business achieved revenue of RMB 14.24 billion, with a year-on-year increase of 14.1% [2] - A total of 621 new molecules were added to the small molecule D&M pipeline in the first three quarters of 2025, bringing the total to 3,430, which includes 80 commercial projects and 87 Phase III clinical projects [2] - The company successfully passed FDA inspections at its Changzhou and Taixing API bases with zero defects in March 2025 [2] Group 3: TIDES Business - The TIDES business (oligonucleotides and peptides) experienced rapid growth, with revenue reaching RMB 7.84 billion, a year-on-year increase of 121.1% [3] - As of September 2025, TIDES' order backlog grew by 17.1% year-on-year [3] - The number of clients served in TIDES D&M increased by 12%, and the number of molecules served rose by 34% [3]