Core Viewpoint - WuXi AppTec focuses on its unique CRDMO business model to efficiently serve global clients and benefit patients worldwide [1] Group 1 - The company emphasizes the importance of its CRDMO business model in generating industry insights quickly [1] - The CRDMO model allows the company to respond promptly to new molecular demands from clients [1] - The commitment to the CRDMO business model is seen as a strategy to ensure the company's long-term development [1]

Core Viewpoint - WuXi AppTec's stock prices surged, with A-shares rising nearly 8% to 106.5 yuan and H-shares increasing nearly 10% to 121.5 HKD, reaching new highs since October of the previous year, following the announcement of expected revenue and profit growth for 2025 [1] Financial Performance - The company anticipates achieving operating revenue of 45.456 billion yuan in 2025, representing a year-on-year increase of 15.84% [1] - Adjusted net profit attributable to shareholders is projected to be 14.957 billion yuan, reflecting a year-on-year growth of 41.33% [1] - Net profit attributable to shareholders is expected to reach 19.151 billion yuan, marking a significant year-on-year increase of 102.65% [1] Business Strategy - The anticipated performance improvement is primarily attributed to the company's focus on its unique "integrated, end-to-end" CRDMO business model [1] - Additional revenue is expected from the sale of stakes in joint ventures and the divestiture of certain business segments, contributing to investment gains [1]

Core Viewpoint - WuXi AppTec (603259.SH) expects significant revenue and profit growth for the fiscal year 2025, driven by its integrated CRDMO business model and increasing client demand for enabling services [1] Financial Performance - The company anticipates a revenue of approximately RMB 45.456 billion, representing a year-on-year increase of about 15.84% [1] - Expected revenue from continuing operations is projected to grow by approximately 21.40% [1] - Adjusted net profit attributable to shareholders is estimated at around RMB 14.957 billion, reflecting a year-on-year growth of approximately 41.33% [1] - The net profit attributable to shareholders, excluding non-recurring gains and losses, is expected to be about RMB 13.241 billion, with a year-on-year increase of approximately 32.56% [1] - Total net profit is projected to reach approximately RMB 19.151 billion, marking a year-on-year growth of about 102.65% [1] - Total profit is expected to be around RMB 23.906 billion, indicating a year-on-year increase of approximately 107.16% [1] - Basic earnings per share are anticipated to be approximately RMB 6.70, reflecting a year-on-year growth of about 104.27% [1] Business Strategy - The company continues to focus on its unique "integrated, end-to-end" CRDMO business model, aiming to meet the growing client demand for enabling services [1] - WuXi AppTec is committed to expanding new capabilities, building new production capacity, and continuously optimizing production processes to enhance operational efficiency [1] - The company aims to drive steady business growth while efficiently empowering clients and delivering more new and effective drugs to global patients [1]

Core Viewpoint - WuXi AppTec expects to achieve approximately RMB 45.456 billion in revenue for the fiscal year 2025, representing a year-on-year growth of about 15.84% [1] - The adjusted net profit attributable to shareholders is projected to be around RMB 14.957 billion, reflecting a year-on-year increase of approximately 41.33% [1] - The net profit attributable to shareholders is estimated to reach approximately RMB 19.151 billion, showing a significant year-on-year growth of about 102.65% [1] Revenue and Profit Growth - The anticipated revenue growth is primarily driven by the company's focus on its unique "integrated, end-to-end" CRDMO business model [1] - The increase in net profit is also attributed to gains from the sale of partial equity in joint ventures and the divestiture of certain business segments [1]

香港交易及結算所有限公司及香港聯合交易所有限公司對本公告的內容概不負責，對其準確 性或完整性亦不發表任何聲明，並明確表示，概不對因本公告全部或任何部分內容而產生或 因倚賴該等內容而引致的任何損失承擔任何責任。 內幕消息 二零二六年度醫療健康大會簡報 本公告由WuXi Biologics (Cayman) Inc.藥明生物技術有限公司*（「本公司」）根據 香港聯合交易所有限公司證券上市規則（「上市規則」）第13.09條及香港法例第 571章《證券及期貨條例》第XIVA部項下內幕消息條文（定義見上市規則）而作出。 本公司將於二零二六年一月十四日（美國太平洋時間）出席第44屆年度摩根大 通醫療健康大會（「年度醫療健康大會」），會上將進行包含本公司業務營運的 若干資訊的簡報（「簡報」）。為確保本公司所有股東及潛在投資者能夠公平及 時地取得該等信息，本公司於本公告納入簡報全文。本公司股東及潛在投資者 務請注意，簡報可能包含前瞻性陳述，該等陳述就其性質而言存在風險及不確 定性，簡報中陳述的任何估計及未來建議均基於若干假設及估計以及管理層 僅根據當前可得資料作出的判斷。 – 1 – 誠如簡報中所披露，本集團業務及財務表現依 ...

Core Viewpoint - WuXi AppTec's performance shows a significant rebound in 2025, with a 84.84% year-on-year increase in net profit attributable to shareholders in the first three quarters, following a "deep U" trend in growth rates over the past few years [1][2][5]. Financial Performance - In the first three quarters of 2025, WuXi AppTec achieved revenue of 32.857 billion yuan, a year-on-year increase of 18.61%, and net profit attributable to shareholders of 12.076 billion yuan, reflecting an 84.84% increase [5]. - The net profit growth rates for the years 2022 to 2025 (first three quarters) were 72.91%, 9%, -1.63%, and 84.84% respectively, indicating a volatile performance trend [2]. Non-Recurring Gains and Losses - The fluctuation in non-recurring gains and losses is a critical factor affecting WuXi AppTec's financial results, with non-recurring losses of 5.38 billion yuan in 2024 and gains of 2 billion yuan in the first three quarters of 2025 [3][7]. - In the first three quarters of 2025, non-recurring gains contributed 2.553 billion yuan to net profit, accounting for 21% of the total [6]. Asset Sale - WuXi AppTec announced plans to sell two wholly-owned subsidiaries for 2.8 billion yuan, with the buyer being Hillhouse Capital, indicating a strategic focus on its CRDMO business model [9]. - The estimated value of the sale is significantly higher than the book value of the subsidiaries, which had a combined net asset value of 969 million yuan [10]. Market Challenges - The company faces challenges due to a tightening financing environment in the global biopharmaceutical industry and potential impacts from the U.S. Biological Safety Act, which is currently stalled in Congress [12]. - Despite these challenges, WuXi AppTec's chemical business remains a strong revenue driver, with a 29% year-on-year revenue increase in the first three quarters of 2025 [12]. Stock Performance and Management Actions - As of November 3, 2025, WuXi AppTec's stock price was 96.41 yuan per share, with a market capitalization of 287.7 billion yuan, reflecting a 3.01% decline [4]. - The company's actual controller announced plans to reduce holdings by up to 2% of total shares, which led to an 8.47% drop in stock price following the announcement [13].

Core Viewpoint - WuXi AppTec has announced the sale of its clinical service subsidiaries, aiming to focus on its CRDMO business model and enhance global capabilities while reporting strong financial performance in the first three quarters of the year [1][2][9]. Group 1: Asset Sale Details - WuXi AppTec plans to sell 100% equity of its subsidiaries, Shanghai Kangde Hongyi Medical Clinical Research Co., Ltd. and Shanghai WuXi Jishi Pharmaceutical Technology Co., Ltd., to Hillhouse Capital for a base price of 2.8 billion yuan [1]. - The two subsidiaries generated approximately 1.16 billion yuan in revenue and 90 million yuan in net profit for the first three quarters of 2025, accounting for 3.5% and 0.7% of WuXi AppTec's total revenue and net profit, respectively [2]. Group 2: Strategic Focus - The sale is part of WuXi AppTec's strategy to concentrate on its CRDMO business model, which includes drug discovery, laboratory testing, and process development, thereby providing financial support for global capacity expansion [2][7]. - The company has been optimizing its business structure over the past year, including the sale of its WuXi ATU business in the U.S. and U.K., which contributed 1.32 billion yuan in revenue for 2024 [3]. Group 3: Financial Performance - For the first three quarters of 2025, WuXi AppTec reported revenue of 32.857 billion yuan, a year-on-year increase of 18.61%, and a net profit of 12.076 billion yuan, up 84.84% [9]. - The chemical segment was the largest revenue contributor, generating 25.98 billion yuan, a 29.3% increase year-on-year [10]. - The U.S. market remains the primary revenue source, with 22.15 billion yuan in revenue, reflecting a 31.9% growth [11].

Core Viewpoint - The article highlights the strong performance of WuXi AppTec, with significant growth in revenue and net profit for the third quarter of 2025, driven by a focus on CRDMO business and strategic asset divestitures [1][2][4]. Financial Performance - WuXi AppTec reported a Q3 revenue of 12.06 billion yuan, a year-on-year increase of 15.26%, and a net profit attributable to shareholders of 3.52 billion yuan, up 53.27% year-on-year [2][6]. - For the first three quarters of 2025, the company achieved a total revenue of 32.86 billion yuan, representing an 18.61% increase, and a net profit of 12.08 billion yuan, which is an 84.84% increase year-on-year [6][9]. Business Growth Drivers - The growth is attributed to the company's continuous focus on and enhancement of the CRDMO business model, optimization of production processes, and increased efficiency from large-scale clinical and commercialization projects [4][5]. - The chemical business segment is identified as the main growth driver, with revenue reaching 25.98 billion yuan, a 29.3% increase, accounting for nearly 80% of total revenue [5]. Strategic Asset Divestiture - WuXi AppTec announced a strategic plan to sell its clinical research service subsidiaries for 2.8 billion yuan to Hillhouse Capital, aiming to focus on core CRDMO areas [15][17]. - The divestiture is expected to generate significant immediate benefits, with estimated gains exceeding 10% of the company's audited net profit for the recent fiscal year [17]. Market Position and Future Outlook - The company has raised its full-year revenue guidance, expecting a growth rate of 17%-18%, supported by a robust order backlog of 59.88 billion yuan, a 41.2% year-on-year increase [10][13]. - The article notes a strong demand for CRO services, with a projected increase in global drug development outsourcing, indicating a favorable market environment for WuXi AppTec [13][14]. Customer Dependency Risks - WuXi AppTec's revenue heavily relies on overseas clients, particularly from the U.S., which poses risks due to geopolitical uncertainties [14]. - The company reported 22.15 billion yuan in revenue from U.S. clients, a 31.9% increase, while domestic revenue only grew by 0.5% to 5.04 billion yuan [14].

Core Viewpoint - WuXi AppTec plans to sell two clinical service subsidiaries, Kangde Hongyi and Jinshi Pharmaceutical, to Hillhouse Capital for a base price of 2.8 billion yuan, as part of its strategy to focus on its core CRDMO business [1][4][8] Financial Performance - For the first three quarters of 2025, the combined revenue of Kangde Hongyi and Jinshi Pharmaceutical was approximately 1.16 billion yuan, accounting for 3.5% of WuXi AppTec's total revenue [5] - The net profit of these subsidiaries was about 90 million yuan, representing 0.7% of the company's net profit for the same period [5] - WuXi AppTec reported a total revenue of 32.857 billion yuan for the first three quarters of 2025, a year-on-year increase of 18.61%, with a net profit of 12.076 billion yuan, up 84.84% [6][7] Business Strategy - The sale of the subsidiaries is part of WuXi AppTec's strategy to concentrate on drug discovery, laboratory testing, and production, while accelerating global capacity expansion [5][8] - The company aims to optimize its financial structure and respond to industry challenges, including increased competition and pricing pressures from peers [9] Market Dynamics - WuXi AppTec's revenue from the U.S. market was 22.15 billion yuan, a year-on-year increase of 31.9%, while revenue from the Chinese market grew only 0.5% [6] - The company has been adjusting its strategy in response to external risks, including the U.S. Biosecurity Act, which has raised concerns about its operations [8][9]

Core Viewpoint - WuXi AppTec is divesting non-core assets, including the sale of two subsidiaries for RMB 2.8 billion, to focus on its CRDMO business model and enhance global capabilities [1][2][3] Transaction Details - WuXi AppTec's subsidiary Shanghai WuXi plans to sell 100% stakes in Kangde Hongyi and Jinshi Pharmaceutical for a base price of RMB 2.8 billion to companies managed by Hillhouse Capital [2][3] - The final transaction price will be adjusted based on the financial status of the companies at the time of the transaction and their performance from 2026 to 2028 [2] Financial Performance - For the first three quarters of 2025, WuXi AppTec reported revenue of RMB 32.857 billion, an increase of 18.61% year-on-year, and a net profit of RMB 12.076 billion, up 84.84% [1][9] - The two divested companies contributed approximately 3.5% to WuXi AppTec's total revenue and only 0.7% to its net profit for the same period [3][9] Strategic Focus - The divestment aligns with WuXi AppTec's strategy to concentrate on drug discovery, laboratory testing, and production services, which is expected to provide funding support for global capacity expansion [3][4] - The company has previously divested from its CGT business and other non-core assets, indicating a trend towards streamlining operations [6][8] Market Reaction - Following the announcement of the asset sale and positive financial results, WuXi AppTec's stock prices increased, with a rise of 2.73% in A-shares and 4.07% in Hong Kong shares [12] Business Segmentation - WuXi AppTec plans to restructure its business segments into Chemistry, Testing, Biology, and Others, moving away from previously distinct high-end treatment categories [8] Future Outlook - The company has raised its revenue guidance for 2025, expecting a growth rate of 17%-18%, up from the previous estimate of 13%-17% [12]