Core Viewpoint - The article discusses the development of a new thrombectomy technique called Milli-spinner thrombectomy, which significantly improves the efficiency of thrombus removal compared to existing methods, potentially transforming treatment for ischemic stroke, heart attacks, pulmonary embolism, and other thrombus-related diseases [4][5][25]. Group 1: Current Thrombectomy Techniques - Mechanical thrombectomy currently fails to clear thrombus in 10%-30% of patients, particularly those with large, fibrin-rich clots [3]. - Existing methods may cause thrombus fragmentation, leading to distal embolization and adverse outcomes [3][8]. Group 2: Milli-spinner Thrombectomy - The Milli-spinner thrombectomy technique is reported to be over twice as effective as current technologies, achieving a 90% success rate in clearing difficult thrombi on the first attempt, compared to approximately 11% with existing devices [5][7]. - This technique utilizes a unique design that applies compressive and shear forces to reduce thrombus volume without causing fragmentation [9][13]. Group 3: Mechanism and Design - The device consists of a hollow, rapidly rotating catheter with fins and slits that create a local negative pressure zone around the thrombus, allowing for effective thrombus reduction [10][15]. - The innovative design allows the thrombus to be reduced to less than 5% of its original volume, enabling red blood cells to flow freely again [16][17]. Group 4: Future Applications and Development - The research team is exploring other potential applications of the Milli-spinner device in the biomedical field, including capturing and removing kidney stone fragments [23]. - A new company has been established to expedite the development and clinical trials of this technology, aiming for rapid approval for patient treatment [24].