数据显示，我国前列腺癌年新发病例13.42万，在男性泌尿生殖系统肿瘤中位列首位，且发病率与死亡 率仍逐年增长，成为威胁中老年男性身心健康的重要疾病之一。龚侃教授表示，前列腺癌的发病风险随 着年龄的增长逐渐升高，规范筛查PSA往往是对抗前列腺癌的警戒线，"建议50岁以上男性定期进行 PSA检测，存在前列腺癌家族史的男性需提前至45岁，争取尽早发现、尽早干预。"目前，规范的PSA 筛查已经使越来越多的早期前列腺癌患者实现临床治愈，但由于前列腺癌早期症状隐匿、社会早筛意识 有待进一步提升，我国前列腺癌患者确诊时已出现远处转移的比例超过30%，整体预后较差。"如何有 效控制晚期患者的疾病进展，延长患者生存期，始终是医学界探索的核心方向"，龚侃教授指出，近年 来新型内分泌治疗药物、靶向药物等创新治疗方案的问世，正在让患者的生存期不断突破，显著改善患 者预后。 在晚期前列腺癌的治疗评估中，PSA的深度速降则是良好预后的关键"信号灯"，"在评估治疗效果时， 我们不仅要看PSA是否下降，还要看PSA是否在早期就实现了快速、深度的下降。研究表明，接受新型 内分泌治疗的患者若在3个月内PSA水平迅速降至0.2ng/mL以下，其无 ...

Core Insights - The incidence of prostate cancer in China is rapidly increasing, posing a significant threat to men's health [1] - Early detection through scientific screening and standardized treatment can lead to long-term high-quality survival for patients [1][2] Group 1: Screening and Diagnosis - Prostate cancer early symptoms are often subtle and similar to benign conditions, making standardized screening crucial [1] - PSA (Prostate-Specific Antigen) testing is currently the most effective screening method [1] - The optimal screening age is between 50 to 75 years, with those having a family history advised to start screening at 45 [1] Group 2: Treatment Advances - Recent advancements in treatment methods for prostate cancer have significantly improved patient outcomes [1] - New endocrine therapy drugs have extended the median overall survival for metastatic hormone-sensitive prostate cancer patients to over 8 years, surpassing traditional medications [1] - The application of targeted and radionuclide therapies further benefits survival for late-stage patients [1] Group 3: Quality of Life and Rehabilitation - Prostate cancer treatment should focus not only on extending survival but also on enhancing the quality of life [2] - Post-surgery rehabilitation, particularly pelvic floor muscle training, is crucial for improving urinary incontinence issues [2] - A multidisciplinary approach to managing bone metastasis has shown significant effectiveness in alleviating pain and preventing fractures [2] Group 4: Public Awareness and Prevention - Prostate cancer is transitioning from a high-mortality tumor to a manageable chronic disease through scientific screening and comprehensive management [2] - There is a need for increased public awareness regarding cancer prevention and the importance of proactive screening [2]