数据显示，我国前列腺癌年新发病例13.42万，在男性泌尿生殖系统肿瘤中位列首位，且发病率与死亡 率仍逐年增长，成为威胁中老年男性身心健康的重要疾病之一。龚侃教授表示，前列腺癌的发病风险随 着年龄的增长逐渐升高，规范筛查PSA往往是对抗前列腺癌的警戒线，"建议50岁以上男性定期进行 PSA检测，存在前列腺癌家族史的男性需提前至45岁，争取尽早发现、尽早干预。"目前，规范的PSA 筛查已经使越来越多的早期前列腺癌患者实现临床治愈，但由于前列腺癌早期症状隐匿、社会早筛意识 有待进一步提升，我国前列腺癌患者确诊时已出现远处转移的比例超过30%，整体预后较差。"如何有 效控制晚期患者的疾病进展，延长患者生存期，始终是医学界探索的核心方向"，龚侃教授指出，近年 来新型内分泌治疗药物、靶向药物等创新治疗方案的问世，正在让患者的生存期不断突破，显著改善患 者预后。 在晚期前列腺癌的治疗评估中，PSA的深度速降则是良好预后的关键"信号灯"，"在评估治疗效果时， 我们不仅要看PSA是否下降，还要看PSA是否在早期就实现了快速、深度的下降。研究表明，接受新型 内分泌治疗的患者若在3个月内PSA水平迅速降至0.2ng/mL以下，其无 ...

Core Insights - The incidence of prostate cancer in China is rapidly increasing, posing a significant threat to men's health [1] - Early detection through scientific screening and standardized treatment can lead to long-term high-quality survival for patients [1][2] Group 1: Screening and Diagnosis - Prostate cancer early symptoms are often subtle and similar to benign conditions, making standardized screening crucial [1] - PSA (Prostate-Specific Antigen) testing is currently the most effective screening method [1] - The optimal screening age is between 50 to 75 years, with those having a family history advised to start screening at 45 [1] Group 2: Treatment Advances - Recent advancements in treatment methods for prostate cancer have significantly improved patient outcomes [1] - New endocrine therapy drugs have extended the median overall survival for metastatic hormone-sensitive prostate cancer patients to over 8 years, surpassing traditional medications [1] - The application of targeted and radionuclide therapies further benefits survival for late-stage patients [1] Group 3: Quality of Life and Rehabilitation - Prostate cancer treatment should focus not only on extending survival but also on enhancing the quality of life [2] - Post-surgery rehabilitation, particularly pelvic floor muscle training, is crucial for improving urinary incontinence issues [2] - A multidisciplinary approach to managing bone metastasis has shown significant effectiveness in alleviating pain and preventing fractures [2] Group 4: Public Awareness and Prevention - Prostate cancer is transitioning from a high-mortality tumor to a manageable chronic disease through scientific screening and comprehensive management [2] - There is a need for increased public awareness regarding cancer prevention and the importance of proactive screening [2]

Core Insights - The "2025 Beijing International Thoracic Surgery Academic Conference" focuses on the latest technologies and challenges in thoracic surgery, aiming to create a high-level academic exchange platform for future development in the field [2] Group 1: Conference Highlights - The conference discusses core diseases such as lung cancer, esophageal cancer, mediastinal tumors, chest wall diseases, and lung transplantation, emphasizing innovations in minimally invasive surgical techniques and perioperative comprehensive treatments [2] - Key topics include the application of targeted therapy and immunotherapy, critical techniques in lung transplantation, donor assessment, rapid recovery concepts, and the role of artificial intelligence in predicting postoperative complications and aiding clinical decision-making [2] Group 2: Lung Cancer Statistics - According to 2022 epidemiological data, lung cancer remains the most prevalent malignant tumor, with approximately 1.06 million new cases, accounting for 22.0% of all malignant tumors, and it has the highest mortality rate [2] - Despite advancements in targeted and immunotherapy drugs extending survival for many advanced non-small cell lung cancer patients, recurrence and metastasis remain significant challenges, highlighting the importance of early detection, diagnosis, and treatment [2] Group 3: Research Findings - A retrospective study presented by Professor Zhang Yi indicates that 10-15% of patients with IA stage lung cancer experience recurrence despite being traditionally considered candidates for surgery without adjuvant therapy [3] - The study suggests that patients with specific high-risk factors who receive adjuvant therapy post-surgery can significantly reduce recurrence rates and extend survival, providing new evidence for personalized precision treatment in early lung cancer [4]

Core Viewpoint - The article emphasizes the rising incidence of urinary system tumors in China, particularly prostate, bladder, and kidney cancers, and highlights the importance of early screening, comprehensive treatment, and multidisciplinary collaboration in cancer prevention and control [1][2]. Group 1: Rising Incidence and Risk Factors - The incidence of urinary tumors is positively correlated with economic development and lifestyle changes, especially in coastal eastern regions of China [2] - High-risk groups include elderly males, individuals with a family history, long-term smokers, and those exposed to chemical pollutants [2] - Smoking is closely linked to kidney and bladder cancers, while poor drinking habits and the consumption of carbonated beverages may also contribute to urinary tumors [2] Group 2: Early Detection and Screening Recommendations - Early symptoms of urinary tumors are often subtle and easily overlooked, necessitating regular screenings starting at age 50 for the general population and at 45 for high-risk individuals [3] - Recommended screening methods include PSA testing for prostate cancer, ultrasound, and urinalysis for bladder and kidney cancers, with further diagnostic procedures as needed [3][4] Group 3: Innovations in Treatment - Advances in targeted therapies, immunotherapy, and robotic surgery are providing new hope for patients [5] - Genetic testing can guide precision medicine, such as using PARP inhibitors for prostate cancer patients with BRCA mutations and antibody-drug conjugates for bladder cancer patients with HER2 overexpression [5] - Robotic-assisted surgeries enhance precision in tumor removal while preserving patient quality of life [5] Group 4: Multidisciplinary Collaboration and Standardization - The multidisciplinary treatment (MDT) model is crucial for managing complex cases, requiring collaboration among various medical specialties [6] - The "China Cancer Integrated Diagnosis and Treatment Guidelines" provides a standardized framework for grassroots hospitals [6] - Shandong University Qilu Hospital promotes resource sharing and standardized treatment through academic exchanges and online consultations [6]