Core Viewpoint - Yunnan Watson Bio (300142) has announced the signing of a revised exclusive sublicensing agreement with Notitia Biotechnologies Company, expanding their collaboration into the "non-patient" field, which aims to enhance the development and commercialization of core microbiome therapies in precision microbiome health and functional nutrition interventions [1] Group 1 - The board of directors of Watson Bio approved the amendment to the exclusive sublicensing agreement with Notitia [1] - The original exclusive sublicensing agreement was signed on May 23, 2025, focusing on the "patient field" [1] - The revised agreement will cover relevant intellectual property and proprietary technology in the non-patient field, indicating a strategic expansion of their partnership [1] Group 2 - The signing of this amendment signifies Watson Bio's dual strategy of "disease treatment intervention" and "chronic disease prevention + health nutrition" [1] - The company aims to establish a comprehensive health solution that encompasses in-hospital treatment, out-of-hospital management, and multi-scenario interventions [1]

Core Viewpoint - Watson Bio (300142.SZ) has signed an amendment to its exclusive sublicense agreement with Notitia Biotechnologies Company to enhance its market competitiveness and expand its core microbiome therapy in the field of precise micro-ecological health and functional nutrition intervention [1] Group 1: Agreement Details - The amendment allows Watson Bio to exclusively develop, manufacture, and commercialize core microbiome analysis, microbiome-targeted transplantation, and nutritional formula technologies in mainland China, Hong Kong, and Macau for non-patient populations [1] - This agreement is based on the upstream licensing agreement that Notitia has with Rutgers University in New Jersey, USA [1] Group 2: Strategic Implications - The signing of this amendment signifies a dual-track layout for the company, combining "disease treatment intervention" with "chronic disease prevention and health nutrition" [1] - The initiative aligns with national policies on non-drug interventions and emphasizes the importance of chronic disease nutrition and prevention strategies [1] Group 3: Market Positioning - The company aims to provide a comprehensive health solution that covers in-hospital treatment, out-of-hospital management, and multi-scenario interventions [1] - This move is expected to integrate existing clinical pathways and underlying technology platform construction, offering diverse product forms to address sub-health and high-risk chronic disease populations [1]

Core Points - Watson Bio announced a board meeting on July 30, 2025, to approve a revised agreement that expands the scope of "core microbiome therapy" into precision microbiome health and functional nutrition intervention [1] - The revision includes granting exclusive rights for development, manufacturing, and commercialization in mainland China, Hong Kong, and Macau for non-patient populations [1] - The financial terms, duration, and due diligence clauses of the agreement have been amended, but the signing will not significantly impact the company's operating performance for the current year [1]