Core Viewpoint - The news highlights the recent research and development activities of Shunlian Bio, particularly in the field of innovative biopharmaceuticals, and the strategic investment by QuanGuo Fund in the company, indicating a shift towards human biological products alongside its traditional focus on animal vaccines [1][9]. Group 1: Company Overview - QuanGuo Fund conducted a survey on Shunlian Bio from August 6 to August 8, 2025, focusing on the company's recent operational status and product development [1]. - Shunlian Bio has invested in Yangzhou Shizhi Yuan Biotechnology Co., which specializes in innovative drug development and clinical trials, with a focus on HIV and allergy treatments [2][5]. Group 2: Product Development - The HIV treatment monoclonal antibody drug (UB-421) is designed to block HIV from entering host cells, showing lower resistance mutation rates compared to existing treatments, and has entered clinical trials in China [3][4]. - The anti-allergy monoclonal antibody drug (UB-221) targets IgE to treat allergic diseases, with ongoing clinical trials for chronic spontaneous urticaria in China [5]. - The herpes simplex virus monoclonal antibody drug (UB-621) aims to provide new treatment options for recurrent genital herpes, with plans for clinical trials based on overseas results [6]. Group 3: Strategic Investment and Future Plans - Shunlian Bio holds a 20.48% stake in Yangzhou Shizhi Yuan and has the right of first refusal for future capital increases or acquisitions [6]. - The company plans to leverage its management and R&D capabilities to accelerate clinical trials and commercialization of innovative drugs [7]. - Shunlian Bio is exploring collaborations with domestic universities for functional cure research and aims to enhance treatment options for patients with low viral loads [4]. Group 4: Market Position and Future Strategy - The company is developing multi-valent vaccines in collaboration with the Chinese Academy of Agricultural Sciences to meet market demands and improve production capacity [8]. - Shunlian Bio's strategic vision includes expanding into the human pharmaceutical market while maintaining a strong focus on animal health products, supported by significant R&D investments [9].

Core Viewpoint - Company has signed cooperation contracts with the Lanzhou Veterinary Research Institute and Zhongnong Weite Biotechnology Co., Ltd. to develop multi-valent vaccines for swine and cattle, addressing the urgent market demand for complex animal disease prevention [1][2][3] Group 1: Cooperation Details - The contracts include the development of two multi-valent vaccines: one for swine (foot-and-mouth disease, swine fever, and pseudorabies) and one for cattle (foot-and-mouth disease, viral diarrhea/mucosal disease, and infectious bovine rhinotracheitis) [1][2] - The cooperation involves shared responsibilities and costs among the parties, with joint ownership of the resulting intellectual property [1][5][8] Group 2: Technical Goals and Methods - The technical goals include obtaining clinical trial approval and new veterinary drug registration for both vaccine projects [3][6] - The development process will follow the Ministry of Agriculture and Rural Affairs' requirements, including research on strains, production processes, and clinical trials [4][6] Group 3: Impact on the Company - This collaboration reflects the company's focus on advanced biotechnology and aims to enhance its competitive position in the animal health sector by providing comprehensive disease prevention solutions [8][9] - The vaccines are designed to reduce the number of immunizations required, thereby saving resources and costs while improving production efficiency [8][9] Group 4: Future Directions - The company plans to strengthen its collaboration with the Lanzhou Veterinary Research Institute and explore the application potential of its research technology platform for other vaccine developments, including mRNA and VLPs vaccines [9]