Core Viewpoint - The case of Zhang Xiaoling highlights significant concerns regarding the reliability of commercial health check-up services, particularly in cancer detection, raising questions about the effectiveness of routine screenings and the potential for misdiagnosis [2][4][27]. Group 1: Company and Service Reliability - Zhang Xiaoling underwent annual health check-ups at Aikang Guobin for ten years without being informed of any cancer risks, despite her eventual diagnosis of advanced kidney cancer [2][8]. - Aikang Guobin stated that they had reviewed Zhang's medical records and found no flaws in their kidney examinations, asserting their lack of responsibility in her case [3][7]. - The incident has sparked public debate about the trustworthiness of commercial health check-up institutions and the adequacy of cancer screening methods [4][27]. Group 2: Screening Limitations - Experts suggest that routine health check-ups primarily identify chronic diseases like hypertension and diabetes, with limited effectiveness in cancer detection [5][29]. - Various screening methods, such as ultrasound and CT scans, have inherent limitations, and a combination of different tests is recommended for more accurate results [5][19]. - The common use of tumor markers like CEA in screenings is criticized, as they are not reliable for early detection of certain cancers, including kidney cancer [11][12][14]. Group 3: Patient Experience and Misdiagnosis - Zhang's experience reflects a broader issue where patients report instances of missed cancer diagnoses despite normal results from commercial health check-ups [6][27]. - Misinterpretation of test results and inadequate communication from health check-up providers can lead to delayed diagnoses and treatment [16][18]. - The case emphasizes the need for better patient education regarding the significance of test results and the importance of follow-up examinations when abnormalities are detected [8][19]. Group 4: Recommendations for Improvement - Medical professionals recommend that individuals, especially those at higher risk, should seek more comprehensive evaluations, including advanced imaging techniques like CT or MRI, rather than relying solely on routine check-ups [30][31]. - Regular health screenings should be tailored to individual health profiles, considering factors such as age, family history, and existing health conditions [30][36]. - The importance of maintaining personal health records and undergoing early cancer screenings is emphasized to improve early detection rates and treatment outcomes [35][36].