Core Insights - The article discusses common skin issues during the late summer and early autumn, emphasizing the impact of high temperatures, humidity, and increased insect activity on skin health [1] Group 1: Common Skin Issues - Common skin problems during this season include sunburn, heat rash, summer dermatitis (such as eczema), and insect bite dermatitis [1] - Sunburn symptoms typically appear 2-6 hours after exposure, including redness, burning, and severe cases may lead to blisters and systemic symptoms like fever and fatigue [1] - Summer dermatitis often manifests as small red bumps or blisters on the limbs, causing intense itching and potential skin thickening and pigmentation changes with repeated episodes [1] Group 2: Prevention and Treatment - To prevent heat rash, it is crucial to maintain a cool environment, bathe frequently, and avoid greasy skincare products [2] - For sunburn, the first 6 hours post-exposure are critical for treatment, involving cool compresses and topical corticosteroids [2] - Insect bite dermatitis can be managed by washing the area immediately and applying soothing treatments like calamine lotion or mild steroid creams [3] Group 3: Specific Recommendations - For heat rash, using refrigerated saline or honeysuckle water can alleviate symptoms, and in cases of pustular heat rash, topical antibiotics may be necessary [2] - For insect bites, immediate washing and cold compresses are recommended, especially for bee stings where the stinger should be removed promptly [3] - Fungal infections in humid conditions can be treated with antifungal creams, while eczema management focuses on skin barrier repair and controlled bathing practices [3]

Core Viewpoint - Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that can lead to multi-organ damage and significantly increase mortality risk, particularly among women of childbearing age in China, where there are over 1 million lupus patients [1][2]. Group 1: Disease Characteristics - SLE is characterized by a "female predominance" with a male-to-female ratio of 1:12, closely linked to estrogen levels [2]. - The disease has two peak age groups: around 15 years during puberty and between 30-45 years during childbearing years, where hormonal fluctuations can exacerbate the condition [2]. - Environmental factors, such as UV exposure and pollutants, are significant triggers for SLE [2]. Group 2: Diagnosis and Symptoms - Early detection and diagnosis are crucial to prevent progression to severe lupus, which has a high mortality rate [3]. - Key warning signs include butterfly-shaped rashes, recurrent oral ulcers, photosensitivity, unexplained joint pain, hair loss, and nail changes [3]. - Regular check-ups, including tests for anti-double-stranded DNA antibodies and antinuclear antibodies, are recommended for asymptomatic individuals [3]. Group 3: Treatment Goals and Strategies - The primary treatment goal for lupus is organ protection, alongside controlling disease activity and minimizing drug toxicity [5]. - Current treatment strategies emphasize individualized care, with a focus on early diagnosis and treatment to achieve stable disease status with minimal medication [4][5]. - The use of biological agents has marked a significant advancement in treatment, allowing for reduced steroid use and lower relapse rates [5]. - It is essential to avoid overtreatment, particularly with steroids and immunosuppressants, to mitigate the risk of severe infections, which are a leading cause of death in lupus patients [5].