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阿尔茨海默病会遗传吗
Ke Ji Ri Bao· 2025-09-25 08:24
Core Insights - The prevalence of Alzheimer's disease among individuals aged 60 and above in China exceeds 5%, and it reaches as high as 30% in those aged 85 and above [1] - Genetic factors play a significant role in Alzheimer's disease, with 5%-10% of cases being hereditary [1] - The presence of pathogenic genes such as APP, PS1, and PS2 indicates a high likelihood (over 95%) of developing Alzheimer's, often at an early age [1] - Risk genes like APOEε4 increase the probability of developing the disease but have a lower chance of being inherited [1] Genetic Testing and Early Detection - It is recommended for children of parents with Alzheimer's to undergo genetic testing to determine the presence of pathogenic or risk genes [2] - Early diagnosis through methods like PET scans and cerebrospinal fluid tests can help in timely intervention with antibody drugs to slow disease progression [2] Prevention Strategies - Prevention of Alzheimer's should begin early in life, emphasizing the importance of good learning habits and cognitive engagement from youth [2] - Building cognitive reserves throughout life is crucial for effectively preventing neurodegenerative diseases [2]