超柔性神经电极

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我国完成自主研发的侵入式脑机接口首例临床试验 意念,从大脑“直达”电脑(探一线)
Ren Min Ri Bao· 2025-06-27 21:49
Core Insights - China's first invasive brain-computer interface (BCI) clinical trial has been successfully conducted, making it the second country globally to enter this phase after the United States [1] - The trial involved a 37-year-old male subject who lost his limbs due to an electrical accident, and he was able to control a computer touchpad through thought after 2-3 weeks of training [1][2] - The developed flexible neural electrodes have a small cross-sectional area and high flexibility, reducing damage to brain tissue [1][2] Group 1 - The BCI device implanted has a diameter of 26mm and a thickness of less than 6mm, allowing for a minimally invasive surgical procedure [2] - The implantation process involves creating a small groove in the skull and inserting ultra-flexible neural electrodes into the brain tissue, taking only 20-30 minutes [2] - The electrodes are designed to collect neural signals accurately by being placed close to the brain's motor cortex [2][3] Group 2 - Precise positioning and implantation are critical for the success of the surgery, achieved through advanced imaging techniques [3] - The research team plans to enable the subject to control a robotic arm for physical tasks, expanding the application of the BCI technology [3]
意念控物已在路上
Jing Ji Ri Bao· 2025-06-21 22:14
Core Insights - The successful initiation of China's first invasive brain-computer interface (BCI) clinical trial marks a significant advancement in the field, positioning China as the second country globally to reach this stage after the United States [1] - The trial involves a male subject who lost all four limbs due to an electrical accident, with flexible electrodes implanted in his brain to decode neural signals for external device control [1][2] Group 1: Clinical Trial Details - The subject underwent a minimally invasive surgery where two ultra-thin flexible electrodes were implanted in the cerebral cortex, connected to a coin-sized implant in the skull [1] - The system allows for wireless transmission of brain signals to external devices, enabling the subject to control a computer using thought after a training period of 2 to 3 weeks [1] Group 2: Technological Innovations - The research team developed flexible neural electrodes that minimize damage to brain tissue, addressing previous challenges of bulkiness and rigidity in BCI devices [2] - These electrodes have demonstrated high-density, wide-range, and long-duration signal acquisition capabilities, overcoming issues related to tissue compatibility and bandwidth limitations [2] Group 3: Surgical Precision - The success of the surgery relies on precise electrode placement, achieved through a combination of functional MRI and CT imaging to create a detailed 3D model of the subject's brain [3] - The surgical process was executed with millimeter-level accuracy to ensure safety and effectiveness [3] Group 4: Future Implications - The invasive BCI system has the potential to significantly improve the quality of life for patients with complete spinal cord injuries, upper limb amputations, and amyotrophic lateral sclerosis once approved for market [3] - Future plans include enabling the subject to control robotic arms and complex physical devices, expanding their functional capabilities [3]
我国成功开展首例侵入式脑机接口临床试验
财联社· 2025-06-14 03:33
Core Viewpoint - The article highlights the successful implementation of China's first invasive brain-computer interface (BCI) clinical trial, marking the country as the second globally to enter this phase of BCI technology [1][3]. Group 1: Clinical Trial Details - The subject of the trial is a male who lost all four limbs due to an electric shock accident. Since the implantation of the BCI device in March 2025, he has achieved functionalities such as playing chess and racing games within 2-3 weeks of training, reaching a level comparable to that of an average person using a computer touchpad [3]. - The BCI system aims to improve the quality of life for patients with spinal cord injuries and amputations through motor function replacement technology [3]. Group 2: Technological Innovations - The neural electrodes developed by the Chinese Academy of Sciences are the smallest and most flexible in the world, with a cross-sectional area only 1/5 to 1/7 of those used by Neuralink, and flexibility exceeding theirs by over a hundred times, minimizing damage to brain tissue [7]. - The BCI implant has a diameter of 26mm and a thickness of less than 6mm, making it the smallest brain-controlled implant globally, about half the size of Neuralink's product. This allows for a less invasive surgical procedure, reducing risks and recovery time [10]. Group 3: Surgical Precision - The success of the surgery relies on precise localization and implantation of the electrodes. Various brain function localization methods were employed, including functional MRI and 3D modeling, to create a detailed functional map of the patient's motor cortex, ensuring accurate implantation [11]. Group 4: Future Applications - The project team plans to enable the subject to use a robotic arm for physical tasks such as grasping and holding objects. Future developments will also include controlling complex physical devices like robotic dogs and intelligent agents to further expand the subject's capabilities [12].
新突破!我国侵入式脑机接口进入临床试验阶段
Di Yi Cai Jing· 2025-06-14 03:12
Core Insights - The article highlights the successful initiation of China's first invasive brain-computer interface (BCI) clinical trial, marking a significant advancement in the field, making China the second country after the United States to enter this phase [1] Group 1: Clinical Trial Details - The clinical trial was conducted by the Chinese Academy of Sciences' Brain Science and Intelligent Technology Center in collaboration with Fudan University Huashan Hospital, focusing on a male subject who lost all four limbs due to an electrical accident [1] - The implanted BCI device has shown stable operation since its implantation in March 2025, with no infections or electrode failures reported over a month [1] - The subject achieved functionalities such as playing chess and racing games within 2-3 weeks of training, demonstrating control comparable to that of a typical user with a computer touchpad [1] Group 2: Technological Advancements - The BCI system developed by the Zhao Zhengtuo and Li Xue teams features the world's smallest and most flexible neural electrodes, with a cross-sectional area only 1/5 to 1/7 that of Neuralink's electrodes, and flexibility exceeding Neuralink's by a factor of 100 [2] - This ultra-flexible electrode allows for high-density, large-area, and long-term stable neural signal acquisition, addressing key challenges in tissue compatibility and bandwidth limitations for implanted BCIs [2] Group 3: Surgical and Operational Efficiency - The BCI system is the only one in China with a registered report that can stably capture single-neuron spike signals, providing a solid data foundation for applications [3] - The device's dimensions are 26mm in diameter and less than 6mm in thickness, making it the smallest brain-controlled implant globally, requiring only a small recess in the skull for implantation, thus reducing surgical risks and recovery time [3] - The standardized operational procedures based on mature surgical techniques facilitate scalable applications in various medical institutions [3] Group 4: Future Applications - The BCI system is designed to achieve similar control levels as Neuralink with fewer implanted electrodes, minimizing patient risk while maximizing benefits [5] - Prior to human trials, the system's safety and functionality were validated in non-human primates, where it successfully controlled computer cursor movement through neural activity [5] - Future plans include enabling the subject to control robotic arms for physical tasks, expanding the potential for interaction with complex devices like robotic dogs and intelligent agents [5]
我国首例侵入式脑机接口临床试验成功
证券时报· 2025-06-14 01:42
近日,我国首例侵入式脑机接口的前瞻性临床试验成功开展,标志着中国在侵入式脑机接口技术上成为继美国之后,全球第二个进入临床试验阶段的国 家。 该项研究由中国科学院脑科学与智能技术卓越创新中心赵郑拓研究组、李雪研究组,联合复旦大学附属华山医院吴劲松、路俊锋团队,以及相关企业合作开展,是 上海市脑机接口临床试验与转化重点实验室2024年12月成立以来的首项重要成果。 据项目团队介绍,该临床试验的受试者是一位因高压电事故导致四肢截肢的37岁男性。自今年3月受试者的大脑植入该脑机接口设备以来,系统运行稳定,术后至 今一个多月未出现感染和电极失效的情况。仅用2—3周的适应性训练,受试者便可以通过意念控制触摸板在电脑上下象棋、玩赛车游戏等,达到了跟普通人控制电 脑触摸板相近的水平。"受试者可以像正常人一样打字、发短信、玩电脑游戏"。 "我们中心组建了脑结构技术与临床应用'十四五'攻关团队,成立了覆盖从运动感知、神经功能修复、解码算法、无线系统研发等多个方向的独立研究组。"赵郑拓 介绍,攻关团队以建制化方式在脑机接口方面的研究自2022年启动,在中国科学院脑科学与智能技术卓越创新中心长达十几年在脑科学研究的积累上,上海在跨科 ...