乐普医疗（300003.SZ）自主研发的聚乳酸面部填充剂已获得国家药监局（NMPA）注册批准。该产品为Ⅲ类医疗器 械，适用于注射于鼻唇沟真皮深层，以纠正中重度鼻唇沟皱纹，属于市场俗称的"童颜针"范畴，是近年国内中高端医美 市场的再生类注射剂主力品类之一。 据统计，该产品是国内第七款、国产第五款获批童颜针。这也标志着乐普医疗正式进军医美再生赛道，根据披露，公司 医美管线还包括注射用重组A型肉毒毒素、多个玻尿酸注射剂型（交联透明质酸钠、复合溶液等），覆盖了"再生填充 —皱纹修复—面部塑形"三大功能分区，形成相对完整的产品链。 值得注意的是，本次童颜针获批背后，乐普医疗业绩持续下滑。2024年，公司净利润2.47亿元同比大幅下滑80.37%，为 2009年上市以来最差业绩；2025年一季度公司净利下滑21.44%。主业疲软、集采压制、商誉减值等问题叠加，迫使公 司战略重心转向消费医疗领域。 能否复制成功 乐普医疗此次获批的聚乳酸面部填充剂为典型的再生医美注射产品，作为III类医疗器械，该品类审批门槛较高。公司在 国产产品中处于第二梯队。头豹研究院预测，2027年中国再生医美填充剂市场将达115.2亿元，年复合增速达 ...

心血管器械龙头乐普医疗正式吹响进军医美赛道的号角。6月3日，公司公告称自主研发的聚乳酸面部填 充剂（俗称"童颜针"）获国家药监局批准上市，成为国产第五款、国内第七款获批的同类产品。这一动 作标志着乐普医疗跨界消费医疗的战略迈出关键一步，同时其肉毒毒素新药也进入审评阶段，双线布局 直指医美市场增量空间。 "童颜针"落地，填补皮肤科领域空白 本次获批的聚乳酸面部填充剂适用于鼻唇沟皱纹填充，通过刺激胶原再生实现长效塑形。乐普医疗在公 告中强调，该产品是公司切入皮肤科领域的"里程碑"，预计将对业绩产生积极贡献。目前国内童颜针市 场已有六款产品竞逐，包括爱美客（300896.SZ）的"濡白天使"、四环医药（00460.HK）的"少女针"以 及进口产品高德美"塑妍萃"等，行业竞争日趋白热化。 器械龙头转型迫在眉睫 乐普医疗的跨界背后是主营业务的增长乏力。财报显示，2024年一季度公司营收17.36亿元，同比下滑 9.67%；归母净利润3.79亿元，同比下降21.44%，业绩已连续多个季度承压。面对集采常态化下医疗器 械行业的利润挤压，公司亟需开辟第二增长曲线——医美、眼科等高毛利消费医疗赛道成为破局关键。 管线纵深布局， ...

据了解，本轮融资将用于推进公司在研产品管线开发，深化在严肃医疗及消费医疗领域的技术布局，加快公司产品管线临床进展、申报进程及市场推广。 君合盟生物制药（杭州）有限公司成立于2020年11月，是一家专注于重组蛋白创新药物及合成生物学领域创新产品开发的生物科技公司，凭借多年的重组蛋 白药物研发及产业化经验，实现了覆盖产品开发全流程的核心技术、平台及人才的积淀，形成了一套完整的技术及产品开发体系。 据介绍，君合盟的研发管线布局围绕严肃医疗、消费医疗、代谢等拥有广阔市场的前沿蛋白药物领域，已实现包括重组I/III型人胶原蛋白原液及制剂、重组 A型肉毒毒素等在内的高端重组蛋白产品的规模化放大，技术水平及产业化进展处于国际领先水平。其中，核心产品重组人生长激素注射液已完成III期临 床；重组A型肉毒毒素已于近日完成成人中重度眉间纹适应症III期临床的首例受试者给药，其用于成人脑卒中后上肢痉挛适应症的II期临床试验也已接近尾 声，即将进入到III期临床。 君合盟CEO徐葵表示：从成立以来，我们始终聚焦严肃医疗与消费医疗领域未满足的临床需求，以自主研发为核心驱动力，构建了覆盖重组蛋白药物全生命 周期的技术平台与产品管线。未来 ...

证券代码：000963 证券简称：华东医药 华东医药股份有限公司投资者关系活动记录表 12.29%，环比2024年第四季度增长24.37%，整体经营符合第一季度计 划目标。国内医美全资子公司欣可丽美学积极拓展国内市场，报告期 内实现营业收入2.54亿元，同比下降1.36%，环比2024年第四季度增长 10.64% 。公司持续深化国内高端医美产品布局，高端玻尿酸 MaiLi®Extreme（商品名：魅俪®朔盈®）将于2025年5月正式实现商业化 销售；多功能面部皮肤管理平台Préime DermaFacial也将于2025年内正 式实现商业化销售。此外，重组A型肉毒毒素YY001、能量源设备V30 及Ellansé®伊妍仕®M型等核心医美产品国内上市申请均已获受理，有 望于2026年获批。依托国内差异化医美产品矩阵的持续丰富，叠加消 费升级带来的市场需求扩容，公司国内医美业务成长潜能将加速释放。 编号：2025-002 | | □特定对象调研 □分析师会议 | | --- | --- | | 投资者关系 | □业绩说明会 □媒体采访 | | 活动类别 | □新闻发布会 □路演活动 | | | □现场参观 ☑其他 ...

Core Insights - The company reported a stable growth trend in Q1 2025, with revenue of 10.736 billion yuan, a year-on-year increase of 3.12%, and a net profit of 915 million yuan, up 6.06% [1] - The pharmaceutical industrial sector continues to be a key growth driver, with core subsidiary China East Pharmaceutical achieving revenue of 3.621 billion yuan, a 6.52% increase, and a net profit of 843 million yuan, up 12.20% [2] - The company is focusing on innovation, with over 80 projects in its pipeline, and has significantly increased R&D investment by 49.60% to 880 million yuan in Q1 2025 [4] Business Segments - The innovative drug sales in the pharmaceutical industrial sector are gaining momentum, particularly with the expansion of reimbursement indications for the Bai Ling series products [2] - The CAR-T product, Zewokaiolun, has shown strong sales performance, with over 200 certified medical institutions and 154 effective orders placed by the partner company [3] - The company’s self-developed GLP-1 receptor agonist, HDM1002, has entered the final stages of clinical trials, indicating a robust pipeline in the endocrine field [5][6] Medical Aesthetics - The medical aesthetics segment is showing resilience, with the subsidiary Sinclair achieving approximately 238 million yuan in revenue, a 24.37% increase from the previous quarter [9] - The company has a portfolio of 40 high-end medical aesthetic products, with 26 already launched globally, indicating a strong market presence [9] - New products in the medical aesthetics field, including injectable products, are expected to drive further growth in 2025 [10] Future Outlook - The company aims to leverage its innovative capabilities and product differentiation to expand its market share in the medical aesthetics sector, which is projected to grow steadily [12] - The pharmaceutical industrial sector is expected to maintain a strong growth trajectory, supported by ongoing market expansion and product pipeline development [12] - The overall performance in Q1 2025 reflects the company's commitment to innovation and growth, positioning it for future success in the pharmaceutical and medical aesthetics industries [12]

Financial Performance - In 2024, the company achieved a revenue of CNY 41.906 billion, a year-on-year increase of 3.16% [4] - The net profit attributable to shareholders was CNY 3.512 billion, up 23.72% year-on-year [4] - The net profit after deducting non-recurring gains and losses was CNY 3.352 billion, reflecting a growth of 22.48% [4] - Compared to 2021, revenue and net profit grew by 21.24% and 52.59%, respectively [4] Business Segments Performance Pharmaceutical Industry - The pharmaceutical segment generated a revenue of CNY 13.811 billion, with a year-on-year growth of 13.05% [5] - The net profit for this segment was CNY 2.876 billion, increasing by 29.04% [5] - R&D investment in the pharmaceutical industry reached CNY 2.678 billion, a 16.77% increase [5] Aesthetic Medicine - The domestic aesthetic medicine subsidiary reported a revenue of CNY 1.139 billion, growing by 8.32% [6] - The UK subsidiary, Sinclair, generated approximately CNY 0.967 billion, a decline of 25.81% due to global economic challenges [6] Industrial Microbiology - The industrial microbiology segment achieved a revenue of CNY 0.711 billion, a significant increase of 43.12% [25] - Growth rates for specific areas included 38% for specialty raw materials and intermediates, 20% for xRNA, and 142% for health and biological materials [25] R&D and Product Development - The company has over 80 innovative drug candidates in its pipeline [5] - The oral small molecule GLP-1 receptor agonist HDM1002 has shown promising results in clinical trials, with over 800 participants [17] - The ADC pipeline includes more than 12 projects, with ongoing clinical trials for several candidates [14] Market Strategy and Future Outlook - The company plans to actively participate in medical insurance negotiations for new products [6] - There is a focus on expanding market presence in both domestic and international markets, particularly in the aesthetic medicine sector [26] - The company anticipates a gradual recovery in overseas aesthetic medicine markets [26] Investor Relations and Communication - The annual performance meeting was attended by 381 institutional and individual investors [2] - The chairman emphasized the commitment to high-quality development and strategic goals for the upcoming three-year plan [27]