阿达木单抗(君迈康®)
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君实生物(01877):PD-1单抗销售明显提速,管线整体进入关键期
Changjiang Securities· 2025-08-29 07:10
Investment Rating - The investment rating for the company is "Buy" and is maintained [6]. Core Views - The company reported a significant increase in sales, with a revenue of 1.168 billion yuan in the first half of 2025, representing a year-on-year growth of 49%. The net loss attributable to shareholders decreased to 413 million yuan, down 36% year-on-year [2][4]. - The sales of the core product, Toripalimab (Tuoyi®), accelerated, generating 954 million yuan in domestic sales in the first half of 2025, a 42% increase year-on-year. The product has received approval for two new indications, totaling 12 indications, with 10 included in medical insurance [6]. - The company has established a comprehensive commercialization network for its core products, with Toripalimab approved in 40 countries and regions globally. The production capabilities are supported by facilities in Suzhou and Shanghai [6]. - The research and development pipeline includes over 50 projects across five therapeutic areas, with nearly 30 in clinical stages. Key products such as JS207 (PD-1/VEGF bispecific antibody) and Tifcemalimab (first BTLA monoclonal antibody) are entering critical clinical phases [6]. - Profitability forecasts indicate net losses of 771 million yuan, 307 million yuan, and a profit of 534 million yuan for 2025, 2026, and 2027, respectively, with corresponding EPS of -0.75 yuan, -0.30 yuan, and 0.52 yuan [6].