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亚虹医药(688176):收入同比增长62% APL-1702国内审评进展顺利
Xin Lang Cai Jing· 2025-09-03 04:37
Core Viewpoint - The company reported a 62% year-on-year increase in revenue for the first half of 2025, driven by the continued growth of commercialized products such as Pazopanib and Neralitinib [2] Financial Performance - The company achieved operating revenue of 130 million yuan, reflecting a year-on-year increase of 61.80% [2] - Sales expenses rose by 45.62% to 113 million yuan, while management expenses increased by 8.95% to 44 million yuan [2] - Research and development expenses decreased by 24.36% to 116 million yuan [2] - The net loss attributable to the parent company narrowed by 11.84% to 162 million yuan [2] - As of the end of Q2 2025, the company had cash reserves of approximately 1.825 billion yuan, providing sufficient funding for future R&D and commercialization [2] Product Development and Regulatory Progress - The domestic review of APL-1702 is progressing smoothly, with expectations for approval by the end of 2025 or early 2026 [2] - The company is actively seeking overseas partners to prepare for the Phase III clinical trial application in the U.S. [3] - Early pipeline products such as DBHi, USP1i, CLDN 6/9-ADC, and FGFR2/3i are advancing steadily [4] - APL-1401 (DBH inhibitor) has completed the dose escalation study in Phase Ib for moderate to severe active UC, showing positive efficacy signals [4] - APL-2302 (USP1 inhibitor) has received approval for Phase I/IIa clinical trials in the U.S. and China, with the first subject enrolled in March 2025 [4] - APL-2501 (CLDN6/9 ADC) is expected to submit an IND by mid-2026, while APL-2401 (FGFR2/3 inhibitor) is in the IND-enabling stage, aiming for clinical approval by the end of 2025 [4] Investment Outlook - The company has a target market value of 8.954 billion yuan, corresponding to a stock price of 15.68 yuan, maintaining a "buy" rating [4]