Core Viewpoint - The article emphasizes the importance of the Cre-loxP system in gene editing research and announces a series of courses aimed at addressing practical issues related to the application of Cre tools in research settings [1][2]. Group 1: Course Announcement - A new session of the "Cre-loxP system combined with AAV applications" course will be held on June 12, featuring experts from the company [2][7]. - The course will focus on questions raised by participants, exploring the core principles of the Cre-loxP system and AAV technology, as well as optimization strategies and case studies [2][4]. Group 2: Technical Insights - The article discusses the advantages of using AAV for delivering Cre recombinase compared to traditional methods involving Cre transgenic mice [4]. - It highlights specific applications where AAV-Cre demonstrates unique benefits, such as in brain neuroscience and organ-specific editing [4]. Group 3: Course Content Overview - The course will cover foundational knowledge of the Cre-loxP system and AAV, technical discussions on their combination, and typical application case studies [12][9]. - Participants will have the opportunity to submit questions for live answers during the course [6][2]. Group 4: Instructor Background - The course will be led by Liu Fanrui, a senior product manager with extensive experience in genetic modification of model organisms, and Xiong Zehao, a project manager specializing in AAV gene therapy [15][17]. Group 5: Additional Resources - A comprehensive manual titled "Cre-loxP Recombinase System User Manual" is available for free, providing detailed insights into the Cre-loxP system [19].