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直播解读:AAV-Cre-loxP基因编辑系统,从原理到应用
生物世界· 2025-06-10 09:45
在基因编辑研究领域, Cre-loxP 系统凭借其精准高效的特性,已成为众多实验室的"标配"。为帮助大家解 决Cre工具鼠应用中的实际问题,我们于数月前开设了两期 Cre系列课程 ,通过 系统讲解+在线答疑 的方 式,获得了众多科研工作者的积极反馈。 这段时间我们注意到,针对Cre-loxP结合AAV的应用问题持续受到大家关注: 为此,工具鼠系列课程将再次返场! 6月12日(周四)晚7点 ,由 赛业生物高级产品经理刘凡瑞、赛业 生物AAV基因治疗项目经理熊泽浩 共同带来 「Cre-loxP系统结合AAV的应用」 主题课程。 本次课程围绕 粉丝朋友们提出的问题展开 ,深入探索Cre-loxP系统与AAV技术的 核心原理 ,解析技术 联用中的 关键优化策略 ,并通过典型应用案例揭示 高分文章背后的实验设计智慧 。扫码提交感兴趣的 问题,讲师将在直播中针对性解答,成功报名课程还可抽取 SKG颈部按摩仪(价值500元) 等好礼! 以下文章来源于赛业生物订阅号 ,作者小赛 赛业生物订阅号 . 分享生命科学领域的前沿资讯、解读行业动态、讲解实用的学科知识、实验方法和技巧。 为什么有的文献选择通过AAV递送Cre酶,而非传 ...
直播预告丨Cre系列课程(三):Cre-loxP系统结合AAV的应用
生物世界· 2025-06-09 03:33
Core Viewpoint - The article emphasizes the importance of the Cre-loxP system in gene editing research and announces a series of courses aimed at addressing practical issues related to the application of Cre tools in research settings [1][2]. Group 1: Course Announcement - A new session of the "Cre-loxP system combined with AAV applications" course will be held on June 12, featuring experts from the company [2][7]. - The course will focus on questions raised by participants, exploring the core principles of the Cre-loxP system and AAV technology, as well as optimization strategies and case studies [2][4]. Group 2: Technical Insights - The article discusses the advantages of using AAV for delivering Cre recombinase compared to traditional methods involving Cre transgenic mice [4]. - It highlights specific applications where AAV-Cre demonstrates unique benefits, such as in brain neuroscience and organ-specific editing [4]. Group 3: Course Content Overview - The course will cover foundational knowledge of the Cre-loxP system and AAV, technical discussions on their combination, and typical application case studies [12][9]. - Participants will have the opportunity to submit questions for live answers during the course [6][2]. Group 4: Instructor Background - The course will be led by Liu Fanrui, a senior product manager with extensive experience in genetic modification of model organisms, and Xiong Zehao, a project manager specializing in AAV gene therapy [15][17]. Group 5: Additional Resources - A comprehensive manual titled "Cre-loxP Recombinase System User Manual" is available for free, providing detailed insights into the Cre-loxP system [19].