DeepGEM
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AI for Science,走到哪一步了?
3 6 Ke· 2025-12-03 09:15
Core Insights - Google DeepMind's AlphaFold has significantly impacted protein structure prediction, driving advancements in scientific research over the past five years [1][4] - AI is reshaping scientific research, particularly in life sciences and biomedicine, due to rich data availability and urgent societal needs [1][3] Group 1: AI in Scientific Research - AI models and tools have achieved breakthroughs in basic research, including protein structure prediction and the discovery of new biological pathways [1][3] - The paradigm of "foundation models + research agents + autonomous laboratories" is emerging in AI-driven scientific research [3][13] Group 2: Advancements in Biology - DeepMind's AlphaFold has solved the protein structure prediction problem, earning the 2024 Nobel Prize in Chemistry and establishing itself as a digital infrastructure for modern biology [4] - The C2S-Scale model, developed by Google and Yale University, has generated new hypotheses about cancer cell behavior, showcasing AI's potential in formulating original scientific hypotheses [8] Group 3: AI in Drug Development - AI-assisted pathology detection has expanded to new disease scenarios, with the DeepGEM model achieving a prediction accuracy of 78% to 99% for lung cancer gene mutations [10] - The AI-optimized drug MTS-004 has completed Phase III clinical trials, marking a significant milestone in AI-driven drug discovery [10] Group 4: AI in Other Scientific Fields - AI applications in materials science are gaining momentum, with startups like Periodic Labs and CuspAI focusing on discovering new materials [11] - DeepMind's WeatherNext 2 model has surpassed traditional physical models in accuracy and efficiency for weather predictions [5] Group 5: Future of AI in Science - The evolution of scientific intelligence technologies is expected to accelerate, with AI foundational models and robotics enhancing research efficiency [19] - The integration of AI into scientific discovery is anticipated to lead to significant breakthroughs, with predictions of achieving near-relativistic level discoveries by 2028 [19]
癌症病理基因大模型DeepGEM落地
Ke Ji Ri Bao· 2025-10-26 23:50
Core Insights - The deployment of the DeepGEM model by Guangzhou Kingmed Diagnostics Group aims to enhance cancer diagnosis through accurate and timely gene mutation predictions [1][2] - The collaboration involves Tencent and Guangzhou Medical University First Affiliated Hospital, focusing on developing a multimodal model for pathology and genetics [1][2] Group 1: DeepGEM Model Development - DeepGEM provides accurate predictions of gene mutations related to lung cancer, achieving a prediction accuracy of 78% to 99% within one minute [1] - The model addresses the challenges of conventional gene testing methods, which are often complex, time-consuming, and costly, particularly in resource-limited areas [1] Group 2: Clinical Application and Future Plans - Following successful validation, the three parties will promote the clinical application of DeepGEM for lung cancer gene mutation prediction [2] - There are plans to further develop a multimodal model that integrates various omics data, including pathology, proteomics, and metabolomics, for AI-assisted diagnosis across multiple cancer types [2] Group 3: Vision and Collaboration - The initiative aims to serve as a model for translating clinical research into practical applications, benefiting the public [2] - Kingmed Diagnostics expresses a desire to collaborate with more partners to create intelligent and accessible clinical diagnostic solutions [2]