Financial Performance - For the full year 2025, Globus Medical reported revenue of $2.939 billion, representing a growth of 16.7% year-over-year, and non-GAAP earnings per share of $3.98, up 30.8% [6][24] - In Q4 2025, revenue reached $826.4 million, growing 25.7% compared to Q4 2024, with non-GAAP EPS at $1.28, a 52.1% increase [7][25] - The adjusted gross margin for Q4 was 69.2%, compared to 67.1% in the prior year quarter, driven by favorable sales mix and synergy execution [30][31] Business Line Performance - The U.S. spine business grew 10% in Q4 2025 compared to the prior year quarter, continuing a trend of above-market growth [8][28] - Enabling Technologies revenue was $55.6 million in Q4, growing 18.5% year-over-year, driven by increased sales of EGPS systems [12][27] - The trauma business delivered approximately 27% growth in Q4, supported by the legacy trauma line and new product launches [16][17] Market Performance - U.S. revenue in Q4 2025 was $665.3 million, growing 27.5% year-over-year, while international revenue was $161.1 million, growing 19% [27][28] - The international spine business faced challenges earlier in the year but showed improvement, culminating in record sales in Q4 2025 [29][83] Company Strategy and Industry Competition - The company aims to expand its core spine business while growing other segments, positioning itself as a procedure-enabling medtech platform integrating imaging, navigation, robotics, and implants [19][20] - The competitive landscape is evolving, with new robotic navigation systems entering the market, but the company believes its ExcelsiusGPS system remains a strong option for customers [13][73] Management Commentary on Operating Environment and Future Outlook - Management expressed confidence in sustained growth momentum, particularly in the U.S. spine business, and anticipates continued above-market growth in 2026 [9][71] - The company expects to achieve a full-year adjusted gross margin of 69%-70% in 2026, reflecting ongoing improvements in manufacturing initiatives [32][43] Other Important Information - The company repurchased approximately 4.3 million shares for $300.5 million during 2025, with a new share repurchase program of $500 million announced [39] - Full-year 2025 SG&A expenses were $1.178 billion, or 40% of sales, with expectations for 2026 to be in the range of 38%-39% [36] Q&A Session Summary Question: Can you bridge the growth expectations for the base business into 2026? - Management noted that 2025 was a tale of two halves, with significant growth in the latter half driven by product launches and sales force expansion [49][50] Question: How do you view market share and the strength of the spine market? - Management believes the U.S. spine business is growing above market and views the overall spine market as relatively healthy [58] Question: What changed in the enabling technology environment? - Management indicated that enabling technology performance was lumpy throughout the year, with a strong Q4 driven by closing delayed pipeline deals [62][63] Question: How sustainable is the U.S. spine growth? - Management sees the growth as durable, supported by ongoing product launches and competitive rep conversions [71][72] Question: What are the headwinds in the international market? - Management identified challenges in the APAC region, particularly Japan, but believes there are ample opportunities for growth in existing markets [82][83]

Company Developments - Globus Medical, Inc. (GMED) has launched DuraPro, a next-generation oscillating system with Excelsius navigation capabilities, aimed at enhancing procedural workflows through improved safety and efficiency [1][8] - The company has introduced 18 new products in 2024, including the ExcelsiusHub and ExcelsiusFlex surgical navigation systems, and expanded its Advanced Materials Science implant portfolio with the COHERE ALIF Spacer in Q1 2025 [3] - The DuraPro system features advanced oscillating technology that prevents soft tissue wrapping and allows for accurate bone removal while protecting delicate tissue [5][8] - GMED has also launched Verzera, a navigated high-speed drill system that integrates with ExcelsiusGPS and ExcelsiusHub, enhancing surgical workflows [6] Financial Performance and Market Outlook - GMED has a market capitalization of $7.56 billion, with 2025 revenue expected to rise by 12.8% year over year according to the Zacks Consensus Estimate [4] - The company has delivered an average earnings surprise of 10.1% over the trailing four quarters [4] - Despite recent product launches, GMED shares have declined by 23.2% over the past year, compared to a 13.7% decline in the industry [11] Industry Trends - The global high-speed surgical drill market is projected to grow from $2.44 billion in 2025 at a compound annual growth rate of 7.8% from 2025 to 2033, driven by the rise in minimally invasive surgical procedures and technological advancements [9]