Financial Data and Key Metrics Changes - The company achieved revenue of $699 million in Q3 2025, resulting in 1% organic growth, with foreign exchange (FX) providing a modest 1% tailwind [24][25] - Adjusted operating margins were 26.1%, slightly above expectations but down 220 basis points year-over-year due to tariffs, FX, and lower volume leverage [25][26] - Adjusted earnings per share (EPS) for the quarter was $1.18, exceeding the midpoint of guidance by $0.05 [6][26] - Free cash flow generated in the quarter was $120 million, representing approximately 90% of adjusted net income [7][8] Business Line Data and Key Metrics Changes - The Signals software business grew 20% organically in the quarter, with strong performance in Software as a Service (SaaS) [5][29] - The reproductive health business grew in the mid-single digits year-over-year, with newborn screening growing in the high single digits [5][31] - The diagnostics segment generated $356 million in revenue, up 3% on a reported basis and 2% organically, with immunodiagnostics declining in the low single digits [29][30] Market Data and Key Metrics Changes - The Americas saw low single-digit growth, Europe experienced mid-single-digit growth, while Asia declined in the mid-single digits, with China down in the low teens [28] - The life sciences segment generated revenue of $343 million, up 1% on a reported basis and roughly flat on an organic basis [28] Company Strategy and Development Direction - The company is focused on disciplined capital deployment, with a new $1 billion share repurchase authorization to replace the existing program [9] - The company is optimistic about future performance, anticipating organic growth of 2% to 4% for the year and adjusted EPS guidance raised to $4.90 to $5.00 [10][33] - The company is actively pursuing AI-driven solutions and strategic partnerships to enhance its product offerings and market position [12][14] Management's Comments on Operating Environment and Future Outlook - Management expressed optimism about improving customer confidence and investment levels in the science sector, despite a stable demand environment [5][19] - The company is cautious in its assumptions until sustained improvements in broader industry demand trends are observed [10][19] - Management highlighted the importance of recent strategic partnerships, including collaborations with Genomics England and Sanofi, which are expected to drive future growth [16][17] Other Important Information - The company reported a 6% reduction in Scope 1 and 2 emissions in 2024 and a 77% employee satisfaction rate [18][19] - The company received a AAA rating from MSCI, indicating strong performance in environmental, social, and governance (ESG) criteria [19] Q&A Session Summary Question: Commentary on 2026 growth outlook - Management indicated a prudent assumption of 2% to 3% organic growth for 2026, with signs of increasing activity in the pharma and biotech sectors [36][37] Question: Insights on life sciences business performance - Management noted that reagents were modestly lower than anticipated, with expectations for a similar market environment moving forward [41][42] Question: Customer activity levels in October - Management observed increasing activity primarily from pharma and biotech customers, particularly in instruments [45][46] Question: EPS growth expectations for 2026 - Management indicated that a 2% to 3% organic growth rate with 28% operating margins would imply high single-digit EPS growth for 2026 [47][48] Question: Confidence in Q4 ramp - Management expressed confidence in the ramp from Q3 to Q4, citing seasonal increases and expected contributions from software and instruments [53][55] Question: China diagnostics outlook - Management confirmed that China diagnostics would continue to face headwinds, with expectations for a return to muted growth levels in the second half of 2026 [76][78]

Financial Data and Key Metrics Changes - The company generated revenue of $665 million in Q1 2025, resulting in 4% organic growth, with a 1% headwind from foreign exchange [27][31] - Adjusted EPS for the quarter was $1.01, exceeding expectations of $0.93 to $0.95 [7][29] - Adjusted operating margins were reported at 25.6%, slightly up year-over-year and above expectations [28] Business Line Data and Key Metrics Changes - Life Sciences segment revenue was $340 million, up 1% reported and 2% organically, with low single-digit growth in pharma biotech customers and a decline in academic and government customers [32] - Diagnostics segment revenue reached $324 million, up 3% reported and 5% organically, driven by high single-digit growth in immunodiagnostics [33] Market Data and Key Metrics Changes - The Americas and Europe experienced mid-single-digit growth, while Asia saw low single-digit growth, with China also growing in low single digits [31] - U.S. academic customers, representing over 5% of total revenue, showed cautious spending due to uncertainties in funding [23][24] Company Strategy and Development Direction - The company is focused on maintaining strong organic growth and operational agility to navigate macroeconomic challenges [5][20] - A recent expanded alliance with Genomics England aims to enhance newborn genomic sequencing capabilities, positioning the company as a leader in this area [9] - The software business, representing about 8% of total revenue, grew over 20% organically in Q1 and is expected to continue strong growth [13][15] Management's Comments on Operating Environment and Future Outlook - Management expressed optimism about the company's resilience and ability to adapt to changing market conditions, reaffirming a full-year adjusted EPS outlook of $4.9 to $5 [19][37] - The company anticipates a gross impact of approximately $135 million from tariffs, but expects to mitigate most of this through proactive measures [18][19] Other Important Information - The company repurchased $154 million of its shares in Q1, reducing the outstanding share count to 119.4 million [7][29] - The net debt to adjusted EBITDA leverage ratio was reported at 2.4 times, with all debt being fixed rate [30] Q&A Session Summary Question: Can you talk about the tariff impact and what products are affected? - Management indicated that they have been proactive in adjusting their supply chain to mitigate the $135 million gross tariff impact, focusing on products sold from the U.S. to China [41][43] Question: What are the expectations for the Life Sciences segment? - The Life Sciences segment is expected to see low single-digit growth, with instrumentation under pressure but solid growth in reagents [45][48] Question: How is the company managing its exposure in China? - The company expects low single-digit growth in China, with a slight decline in Life Sciences and mid-single-digit growth in Diagnostics [56] Question: What is the outlook for the software business? - The software business is expected to continue strong double-digit growth, with a focus on expanding into new markets [62][90] Question: What are the long-term margin expectations? - Long-term operating margin expectations remain unchanged, with a focus on SG&A volume leverage as growth continues [104]