传统市场经常期货绞杀事件，大多数都是多头胜利，因为空头会存在天然的劣势，随着上涨保证金需要成倍的增加。很多时候期货价格也被打到非常离谱的价格，22年青山集团的镍就是。更别说币圈这种妖魔鬼怪的地方了，什么都有可能发生。之前trb不就是，币安500，ok750，巨大的价差，套利的一夜回到解放前。Hype是没有指数价格的，大持仓低流动性（20年以前的币圈），很容易连环爆，万一发生了，可能又是币安0.012，hype0.015这样。持续短短1分钟这样，你来不及补仓，仓位就无了，然后等你想重新开回来的时候，已经插针了。主要是想说，套保是可以，但是不要把自己放在一个很被动的地方，很多人老问我1x套保可以不可以，大多数情况是安全的。但是如果发生连环清算呢，你是不是就一夜回到解放前了。 ...

Core Insights - HCW Biologics has developed second-generation, multi-specific T-cell engagers targeting pancreatic cancer, utilizing its proprietary TRBC product discovery platform, which activates T cells and reduces immunosuppression in the tumor microenvironment [1][2][3] Company Overview - HCW Biologics Inc. is a clinical-stage biopharmaceutical company focused on developing novel immunotherapies aimed at chronic inflammation and age-related diseases, with a belief that their products can significantly change cancer treatment and improve patients' quality of life [4][5] - The company has created over 50 molecules using the TRBC platform, which allows for the construction of various classes of immunotherapeutic compounds, including multi-functional immune cell stimulators and multi-specific targeting fusions [5] Product Development - The lead product candidate, HCW9302, was developed using the legacy TOBI platform, while the TRBC platform is designed to create immunotherapeutics that activate immune responses and specifically target cancerous cells [4][5] - The two lead T-cell engagers target tissue factor and mesothelin, demonstrating potent anti-pancreatic cancer activities in preclinical studies, with 100% survival in treated tumor-bearing mice [2][3]

Core Viewpoint - HCW Biologics Inc. has regained compliance with Nasdaq's listing requirements, ensuring its continued presence on the Nasdaq Capital Market [1][2]. Company Overview - HCW Biologics Inc. is a clinical-stage biopharmaceutical company focused on developing innovative immunotherapies targeting chronic inflammation and related diseases [3]. - The company aims to improve healthspan and quality of life by addressing age-related and senescence-associated diseases through its proprietary drug platforms [3]. Compliance Details - On June 24, 2025, HCW Biologics received formal notice from Nasdaq confirming compliance with the minimum stockholders' equity requirement [2]. - The company had previously regained compliance with other Nasdaq requirements, including bid price, public float, and market value of publicly held shares [2]. Product Development - The lead product candidate, HCW9302, was developed using the TOBI™ platform, while the TRBC platform allows for the creation of various immunotherapeutic compounds [3]. - The TRBC platform has produced over 50 molecules, with ongoing preclinical evaluations for selected candidates based on early promising data [3].

Core Insights - The WeClone project has gained significant attention as a solution for creating digital avatars based on WeChat chat records, utilizing large language models and fine-tuning techniques [1][2][3] - The project leverages RAG knowledge base principles to import WeChat chats and fine-tune models, enabling users to generate personalized digital personas [2][3] - The project is open-source and has garnered 8.7k stars on GitHub, indicating strong community interest and engagement [1] Project Overview - WeClone allows users to create digital avatars from their WeChat chat records, which are considered personal and detailed knowledge bases [3][7] - The project employs a default model, Qwen2.5-7B-Instruct, and utilizes LoRA for fine-tuning, requiring approximately 16GB of GPU memory [2] - The project includes features for automatic speech recognition (ASR) and text-to-speech (TTS), enabling the digital avatar to mimic the user's voice [2] Applications and Use Cases - The project can generate digital personas for various roles, including customer service representatives, marketing agents, and financial advisors, by utilizing chat records as knowledge bases [7] - Digital avatars can help reduce costs in customer service by automating responses based on accumulated chat data, thus eliminating the need for separate knowledge base management [7] - The ability to create tailored digital personas for different industries and roles enhances the effectiveness of communication and service delivery [7] Technical Implementation - Users can extract WeChat chat records using PyWxDump, with specific instructions for data migration and export in CSV format [6] - The project supports customization of dialogue names and system prompts, allowing users to personalize their digital avatars further [5] Community Engagement - The project encourages community participation by inviting users to join development groups for sharing product design cases and contributing to the development of digital personas [8]

以下文章来源于JackCui ，作者JackCui JackCui . 一名热爱技术的算法工程师。分享技术，乐享生活：技术、快乐、财富。 你的微信里有没有一个对话窗？它很久都没有弹出新消息，但你却常常在深夜里点开反反复复地翻着。 如果现在，你可以用这些聊天记录克隆出对方的"数字分身"，保存下 TA 说话的语气、风格、独特的口 头禅，甚至还能给你发来语音，你会怎么选？ 最近，GitHub 上新开源了一个项目 WeClone——让你记忆里的那个 TA 在数字世界里永生，已不再是不 可能。 WeClone 通过个人微信聊天记录对大语言模型（ LLM ）进行微调，打造个性化的数字分身。 除了留住记忆里的 TA，你也可以创造自己的数字分身。 你有没有想过，和自己聊天会是什么样的体 验？你会喜欢和自己聊天吗？ | O | 17 | 0 | ılıl 1.9K | W | T | | --- | --- | --- | --- | --- | --- | | | Vic Huang @bugauwIQtoa5ftS · Apr 11 | | | C | ... | | 数字永生 | | | | | | | 0 | 5 | ...