Tinengotinib(TT00420)

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【港股IPO】6月9日-6月10日,港交所IPO动态,5家企业通过聆讯、2家企业递表
Sou Hu Cai Jing· 2025-06-10 11:20
Group 1: IPO Approvals - Five companies have successfully passed the IPO hearing on June 9-10, including Yaojie Ankang, Yingtong Holdings, Saint Bella, Xiangjiang Electric, and Cao Cao Mobility [1] - Two companies, Guangzhou Yinnuo Pharmaceutical Group and Shenzhen Chuangzhixin Lian Technology, have submitted their IPO applications [12][13] Group 2: Yaojie Ankang - Yaojie Ankang is a biopharmaceutical company focused on developing innovative therapies for tumors, inflammation, and cardiovascular metabolic diseases [1] - The company's core product, Tinengotinib, is a multi-target kinase inhibitor currently undergoing two pivotal clinical trials for cholangiocarcinoma [2] Group 3: Yingtong Holdings - Yingtong Holdings is the largest perfume group in China (including Hong Kong and Macau) excluding brand owners [3] - The company operates a comprehensive sales and distribution network across over 400 cities in China, leveraging both offline and online channels [4] Group 4: Saint Bella - Saint Bella is a leading postpartum care and recovery group in China, aiming to become a comprehensive family care brand in Asia [6] - The company is recognized as the largest postpartum care group in Asia based on revenue from maternity centers [7] Group 5: Xiangjiang Electric - Xiangjiang Electric is a manufacturer of household appliances in China, primarily operating under ODM/OEM models [8] - The company ranks as the tenth largest in the kitchen small appliances sector in China, with a market share of 0.8% [8] Group 6: Cao Cao Mobility - Cao Cao Mobility is a ride-hailing platform incubated by Geely Group, operating in 136 cities as of December 31, 2024 [10] - The company's total gross transaction value (GTV) reached RMB 12.2 billion in 2023, reflecting a 37.5% increase from 2022 [10] Group 7: Guangzhou Yinnuo Pharmaceutical - Guangzhou Yinnuo Pharmaceutical focuses on developing therapies for diabetes and metabolic diseases, with a core product targeting type 2 diabetes [12] - The company has a pipeline that includes several candidates in clinical and preclinical stages [12] Group 8: Shenzhen Chuangzhixin Lian Technology - Shenzhen Chuangzhixin Lian is a leading provider of metallization interconnect plating materials and key process technologies in China [13] - The company is recognized as the largest domestic supplier of wet process plating materials in the Chinese market [13]
药捷安康通过港交所聆讯 两年累计亏损超6亿元人民币
Zhi Tong Cai Jing· 2025-06-09 23:24
Core Viewpoint - The company,药捷安康, is undergoing a listing process on the Hong Kong Stock Exchange, with a focus on developing innovative therapies for cancer and other diseases, while currently not generating any revenue from product sales [1][4][7]. Company Overview - 药捷安康 is a biopharmaceutical company focused on discovering and developing small molecule therapies for oncology, inflammation, and cardiovascular metabolic diseases [4]. - The company has developed a core product, Tinengotinib (TT00420), which is a multi-target kinase (MTK) inhibitor targeting key pathways including FGFR/VEGFR, JAK, and Aurora kinases [4]. Clinical Development - Tinengotinib is currently undergoing two pivotal/registration clinical trials for cholangiocarcinoma (CCA) in patients who have progressed after FGFR inhibitor treatment, with one trial in China and another involving the US [4]. - The company is also exploring Tinengotinib for other indications such as metastatic castration-resistant prostate cancer (mCRPC), breast cancer, and hepatocellular carcinoma (HCC) [5]. Market Potential - The global CCA drug market is projected to reach $2 billion by 2024, with a compound annual growth rate (CAGR) of 16.2% from 2019 to 2024, and further growth expected to $3.2 billion by 2027 [4]. Financial Performance - The company reported revenues of approximately 1.18 million RMB in 2023, with no revenue expected in 2024, and incurred significant operating losses of 343.39 million RMB and 274.61 million RMB for the respective years [7][9]. - The financial data indicates that the company has not yet achieved profitability and relies on milestone payments from partnerships for revenue [7].