Boston Scientific (NYSE:BSX) FY Conference January 13, 2026 12:00 PM ET Company ParticipantsMike Mahoney - Chairman and CEOKen Stein - Senior VP and Chief Medical OfficerJon Monson - EVP and CFOConference Call ParticipantsRobbie Marcus - Medtech Senior AnalystRobbie MarcusHello, everyone. Welcome. I'm Robbie Marcus, the MedTech Analyst at JPMorgan. Really happy to host Boston Scientific. We have Mike Mahoney, CEO, Jon Monson, CFO, and Dr. Stein, Chief Medical Officer. We're going to do a fireside chat here. ...

Core Insights - Parnassus Investments reported that the S&P 500 Index increased by 8.12% in Q3 2025, driven by investor optimism regarding monetary easing, strong consumer demand, and solid corporate earnings [1] - The Parnassus Core Equity Fund (Investor Shares) returned 2.57% in Q3 2025, underperforming the S&P 500 Index, and has a year-to-date return of 9.89% compared to the index's 14.83% [1] Company Highlights - Boston Scientific Corporation (NYSE:BSX) experienced a one-month return of -4.86% but gained 5.89% over the last 52 weeks, with a market capitalization of $142.952 billion as of December 22, 2025 [2] - The company reported consolidated revenue of $5.065 billion for Q3 2025, reflecting a 20.3% growth compared to Q3 2024 [4] Investment Strategy - The Parnassus Core Equity Fund made strategic moves in the Health Care sector by trimming positions in Eli Lilly and Stryker to initiate a position in Boston Scientific Corporation, citing its first-mover advantage and robust clinical data as key growth drivers [3] - Management's focus on disciplined R&D and M&A has led to organic sales growth and margin expansion, positioning Boston Scientific for durable growth [3]

Boston Scientific Corporation (NYSE:BSX) is one of the best healthcare AI stocks to buy now. On December 12, TD Cowen reaffirmed a Buy rating on Boston Scientific Corporation (NYSE:BSX) and kept a $115 price target. The firm went a step further to name Boston Scientific their “Best Idea for 2026.” TD Cowen Names Boston Scientific (BSX) Top 2026 Pick, Reaffirms Buy Image: Courtesy of Boston Scientific TD Cowen called Boston Scientific “the most attractive growth story in the medical devices sector.” The ...

Financial Data and Key Metrics Changes - The electrophysiology (EP) business has experienced significant growth, with FARAPULSE driving growth at approximately twice the market rate since its introduction in the EU in 2021 [2][4] - The U.S. market penetration for FARAPULSE has quickly surpassed 50%, indicating strong adoption and market presence [4][5] Business Line Data and Key Metrics Changes - The FARAPULSE ecosystem, including FARAWAVE catheter and Opal mapping system, has been pivotal in driving success across global markets [2][3] - The Watchman franchise is projected to be a long-term growth engine for the company, with expectations of over 20% growth depending on the outcomes of OPTION and CHAMPION trials [14][17] Market Data and Key Metrics Changes - The global electrophysiology market is valued at $13 billion, with $9 billion attributed to atrial fibrillation (AF) and $4 billion to other indications [9] - The renal denervation market is being re-evaluated, with hypertension being a common condition affecting one in four adult Americans, presenting a significant opportunity for device-based therapies [38] Company Strategy and Development Direction - The company is focused on expanding its leadership in the electrophysiology market while exploring adjacent markets such as diabetes [9][10] - There is a strategic emphasis on category leadership across various medical technology segments, including interventional cardiology and structural heart [62][63] Management's Comments on Operating Environment and Future Outlook - Management acknowledges the competitive landscape in cardiology, emphasizing the importance of understanding competition and focusing on their ecosystem of products [10][12] - The company is preparing for a shift of inpatient procedures to outpatient settings, aligning with CMS goals to enhance accessibility [47][48] Other Important Information - The company is investing in artificial intelligence to enhance product development and operational efficiency, with applications in imaging and electrophysiology [59][61] - The upcoming CHAMPION trial is expected to significantly expand the eligible patient population for the Watchman device, potentially tripling its total addressable market to $6 billion by 2030 [17][18] Q&A Session Summary Question: What is the growth outlook for the Watchman franchise? - The Watchman franchise is expected to grow over 20% long-term, contingent on positive outcomes from the OPTION and CHAMPION trials [14][17] Question: How does the company view the competitive landscape in electrophysiology? - The company recognizes the competitive nature of the market but believes it has a strong understanding of upcoming competition and is focused on its product ecosystem [10][12] Question: What is the timeline for the Seismic device and clinical data? - The Seismic device is currently enrolling in the Fracture ID study, with completion anticipated in Q1 2026 and a commercial launch expected in the first half of 2027 [30][31] Question: How does the company plan to address the access issues in renal denervation? - The company plans to focus on educating both physicians and patients about the therapy, which is crucial for market development [45][46] Question: What are the expectations for the CRM market? - The CRM market is currently the lowest growth area for the company, but a complete revamp of the CRM portfolio is underway, aiming for at or above market growth [50][52]

Financial Data and Key Metrics Changes - The company reported strong growth in the electrophysiology (EP) business, with growth rates approximately double the market average, driven by the FARAPULSE ecosystem [2][5] - The approval of persistent atrial fibrillation (AF) in the U.S. is expected to further enhance market penetration [5] Business Line Data and Key Metrics Changes - The FARAPULSE product line has seen significant adoption, particularly in the U.S. where penetration quickly surpassed 50% [4] - The Watchman franchise is projected to grow at over 20% annually, contingent on positive outcomes from the OPTION and CHAMPION trials [13][17] Market Data and Key Metrics Changes - The global electrophysiology market is valued at $13 billion, with $9 billion attributed to AF and $4 billion to other indications [9] - The renal denervation market is being revisited due to evolving clinical data and the high prevalence of hypertension, with one in four adult Americans affected [37] Company Strategy and Development Direction - The company aims to maintain category leadership across various medical device segments, including interventional cardiology and electrophysiology [67] - There is a focus on expanding the FARAPULSE ecosystem and entering adjacent markets, with a strong emphasis on innovation and product development [1][9] Management's Comments on Operating Environment and Future Outlook - Management acknowledges a highly competitive landscape in cardiology but expresses confidence in their understanding of upcoming competition and their strategic positioning [10][12] - The company is preparing for a shift of inpatient procedures to outpatient settings, aligning their product ecosystem accordingly [48][49] Other Important Information - The company is actively investing in artificial intelligence to enhance product development and operational efficiency [61][64] - The upcoming CHAMPION trial is expected to significantly impact the Watchman market, potentially expanding the eligible patient population to approximately 20 million globally [17] Q&A Session Summary Question: What is the long-term growth outlook for the Watchman franchise? - The Watchman franchise is expected to grow over 20% annually, depending on the outcomes of the OPTION and CHAMPION trials [13][17] Question: How does the company view the competitive landscape in electrophysiology? - The company recognizes the competitive nature of the market but believes their unique product offerings and ecosystem will maintain their leadership position [10][12] Question: What is the timeline for the Seismic device in interventional cardiology? - The Seismic device is currently enrolling in the Fracture ID study, with a commercial launch anticipated in the first half of 2027 [30]

Summary of Boston Scientific Conference Call Company Overview - **Company**: Boston Scientific - **Key Executives Present**: Dr. Ken Stein (Chief Medical Officer), Lauren Tengler (Head of Investor Relations) Key Industry Insights 1. Growth Drivers - Focus on key growth drivers including the Watchman device and the ablation portfolio [2][10] - Anticipated sustained double-digit growth for Watchman despite recent trial results [8][11] 2. Recent Trial Results - The closure trial for left atrial appendage closure (LAAC) was negative, failing to meet non-inferiority to best medical therapy [2][4] - High procedural-related complications and early bleeding were significant issues in the trial [4][5] - Only half of the devices used in the trial were Watchman devices, with many being older generation devices known for higher risks [3][4] 3. Positive Outcomes from Trials - Despite the negative closure trial, there was an equivalent rate of ischemic stroke in high-risk populations compared to best medical therapy [4][5] - The PROG-17 trial showed more favorable outcomes for LAAC, indicating potential operator experience differences [5][6] 4. Market Dynamics - The company sees no impact on Watchman growth from recent trials, as they provide patients with more reasons to seek AF ablation [10][11] - The proportion of Watchman implants that are concomitant procedures is expected to reach 25% by the end of 2025 [20][21] 5. Future Trials and Expectations - The Champion trial is expected to present results in the first half of 2026, which could reinforce confidence in current indications and expand market growth [12][15] - A positive outcome from Champion could lead to changes in reimbursement and guidelines, enhancing market penetration [16][17] Product Insights 1. Watchman Device - Watchman is accelerating in the U.S. market, particularly due to the OPTION trial and improved CMS coverage [19][20] - The device is being increasingly offered to high-risk stroke patients undergoing ablation procedures [20][21] 2. FARAPulse Technology - FARAPulse is gaining traction in both de novo paroxysmal and persistent AF ablation procedures [29][30] - The company is seeing a shift towards lower redo rates in ablation procedures, with single-digit redo rates reported [30][31] 3. Competitive Landscape - Boston Scientific's Opal mapping system is positioned to compete effectively against incumbents, offering unique advantages for PFA procedures [32][33] - The company anticipates that the AF ablation market will continue to grow, driven by underpenetration and the increasing use of new technologies [34] 4. Other Growth Areas - The company is optimistic about its renal denervation technology and the potential for ultrasound-based devices to improve safety and efficacy [36][37] - Other promising areas include drug-coated balloons and interventional oncology, particularly with Y90 beads for treating solid tumors [39][40] Conclusion - Boston Scientific is positioned for continued growth in the healthcare sector, particularly in electrophysiology and ablation technologies, despite recent challenges in clinical trials. The company is focused on leveraging positive trial outcomes and expanding its product offerings to capture a larger market share.

CVRx Conference Call Summary Company Overview - **Company**: CVRx - **Industry**: Cardiovascular medical devices - **Product**: Barostim, a neuromodulation therapy for heart failure - **Annual Total Addressable Market (TAM)**: $2.2 billion [1][5] Key Points and Arguments Heart Failure Market - Heart failure leads to over 1 million hospitalizations, 1.3 million emergency room visits, and 8 million physician office visits in the U.S. annually, with spending projected to reach approximately $70 billion by the end of the decade [1] - Heart failure is a progressive disease with significant mortality rates, exceeding those of the top five cancers [1] Treatment Landscape - Current treatment involves quad therapy (four Class I drugs), but only 1% of patients reach therapeutic doses, and 40% discontinue at least one drug within the first year [3] - Patients express a preference for a higher quality of life over mere life extension [4] - Barostim targets the "forgotten middle" of heart failure patients, aiming to restore quality of life [4] Clinical Evidence and Efficacy - Barostim has shown a 68% improvement in New York Heart Class functional status and a 94% response rate among patients [10] - A real-world study indicated an 85% reduction in hospitalization rates post-implantation of Barostim [11] - The therapy operates by restoring signaling from baroreceptors to the brain, effectively reducing sympathetic tone and neurohormonal toxicity [8][9] Go-to-Market Strategy - CVRx is focusing on building a specialized sales organization and deepening adoption in targeted accounts rather than broad distribution [12][13] - The company has identified 300-400 centers in the U.S. with the highest potential for Barostim adoption based on patient volume and experience with similar devices [15][16] Barriers to Adoption - Key barriers include therapy awareness, clinical evidence, patient access, and reimbursement issues [18][19] - Significant outreach efforts are being made to educate referral physicians and advanced practice providers [20] Reimbursement Developments - Secured a permanent inpatient DRG reimbursement of $43,000 and an outpatient code at $45,000 [24] - Transitioning to a permanent category one procedural code on January 1, which will enhance payment certainty for surgeons and reduce prior authorization denials [25][26] Financial Performance - Reported Q3 revenue of $14.7 million, with guidance for Q4 revenue between $15 million and $16 million [27] - Gross margin reported at 87%, with a cash balance of $85 million [27] Additional Important Information - The therapy has a remarkable 97% freedom from complications during implantation [9] - The company is actively generating further clinical evidence to support the therapy's efficacy and safety [21][22][23]

Core Insights - Boston Scientific Corp. (NYSE:BSX) is recognized as a strong investment opportunity by Citadel LLC, with a reiterated price target of $115 and a Buy rating from TD Cowen analyst Josh Jennings following the company's robust Q3 2025 results [1][2]. Financial Performance - The company achieved a notable 15.3% organic growth in Q3 2025, surpassing its own guidance, primarily driven by strong performance in the Electrophysiology and Watchman businesses within the Cardiology segment [2]. - This organic growth contributed to stronger sales and earnings per share (EPS), allowing the company to exceed market expectations [2]. Future Outlook - Boston Scientific has raised its guidance for growth and profitability for the third time this year, projecting organic sales growth of approximately 20% on a reported basis and 15.5% on an organic basis for 2025, an increase from the previous guidance of 18%-19% and 14%-15% respectively [3]. - The company also maintains a positive outlook on margins, reinforcing a bullish perspective on its future performance [3]. Company Overview - Boston Scientific is a global medical technology company that develops, manufactures, and markets a diverse range of medical devices aimed at diagnosing and treating complex cardiovascular, respiratory, oncological, neurological, and urological diseases and conditions [4].

Core Insights - Boston Scientific Corporation (NYSE:BSX) is identified as a strong investment opportunity with a Buy rating and a price target of $132 as of October 23, 2023 [1][2] Financial Performance - The company reported fiscal third quarter 2025 results on October 22, exceeding EPS and revenue estimates by $0.04 and $90.87 million, respectively [2] - The EPS of $0.75 surpassed the firm's estimate of $0.70, attributed to significant improvements in gross margins [2] Growth Projections - Boston Scientific raised its full-year guidance, projecting a 20% growth and an adjusted EPS in the range of $3.02 to $3.04 [3] - Key growth drivers include the Watchman and Farapulse products, ongoing investments in growth, and anticipated label expansions of existing products [3] Company Overview - Boston Scientific develops and markets medical devices across various interventional specialties, addressing conditions in gastrointestinal, urological, neurological, and cardiovascular areas through minimally invasive technologies [4]

Core Insights - Netflix's third-quarter earnings fell short of expectations, primarily due to a one-time tax charge exceeding $600 million related to its operations in Brazil, leading to a 10.1% drop in its shares [5][8] - Intuitive Surgical experienced a significant increase in its stock price by 13.9% after reporting better-than-expected quarterly results, driven by a rise in procedures using its robotic surgical systems [7][8] - Major U.S. equity indexes declined, with the S&P 500 down 0.5%, the Dow down 0.7%, and the Nasdaq down 0.9%, influenced by the underperformance of tech stocks and anticipation of Tesla's earnings report [3][7] Company-Specific Summaries - **Netflix (NFLX)**: Reported lower-than-expected net income for Q3, impacted by a substantial tax expense related to Brazil, resulting in a significant share price decline [5][8] - **Intuitive Surgical (ISRG)**: Achieved strong quarterly sales and profit figures, leading to a notable increase in stock price, and raised its full-year growth forecast for procedures [7][8] - **Lennox International (LII)**: Experienced a 10.2% drop in shares due to disappointing quarterly sales, attributed to a challenging macroeconomic environment and regulatory changes [4] - **Coinbase Global (COIN)**: Shares fell 5.4% as major cryptocurrencies declined, with Bitcoin dropping below $110,000 [6] - **Avery Dennison (AVY)**: Reported better-than-expected results, leading to a 9.5% increase in shares, supported by improved pricing and a partnership with Walmart [9] - **Boston Scientific (BSX)**: Shares rose 4% after surpassing sales and profit estimates, benefiting from strong sales of its medical devices [10]