（编辑 王雪儿） 证券日报网讯 华大基因9月10日在互动平台回答投资者提问时表示，公司目前正处于业务转换的关键时 期，在这个过程中，公司针对基因检测及测序行业普遍存在的痛点问题，如操作复杂、成本较高、解读 和咨询壁垒较高等，加大了研发布局与投入力度，致力于全面推动自动化和智能化能力的提升。在原有 业务方面，公司在生育健康、肿瘤和传感染防控等多个医学检测领域已进行了长期布局。公司在今年发 布的基于"133111i"核心技术支撑的"i99智健系统"，将助力公司的业务从精准医学领域全面延伸至精准 健康管理领域，进一步拓展业务边界，提升服务价值。 ...

Core Viewpoint - The article emphasizes that "AI healthcare" is becoming a core metric for recalibrating value in the capital market amidst global industrial chain restructuring and intensifying technological competition [1]. Financial Performance - BGI reported a total revenue of 1.631 billion yuan and a net profit attributable to shareholders of 5.7782 million yuan for the first half of 2025, with a net profit of 58.4733 million yuan in the second quarter, representing a year-on-year increase of 908.64% [1]. Market Expansion - The company's precision medicine business is expanding internationally, with revenue from emerging markets in Latin America and South Asia doubling [1]. - BGI is optimizing its product matrix, with high-margin non-invasive products rapidly gaining market traction [1]. AI Integration - BGI is leveraging AI to empower its operations, transforming AI healthcare from a concept into a driving force for innovation [1]. - The GeneT intelligent analysis system significantly enhances the efficiency of genetic disease diagnosis, accelerating the clinical application of gene sequencing [7]. Public Service and Data Strategy - BGI's ChatGeneT platform provides reliable interpretations in genetic disease analysis and is positioned as a new infrastructure for public health management [8]. - The launch of comprehensive tumor databases marks a significant step in data assetization, supporting various clinical and research applications [8]. Strategic Shift to Consumer Market - BGI is shifting its focus towards the consumer market, aiming to create a dual-driven growth model of "B+C" [10]. - The company has restructured its internet hospital to integrate online and offline health management services, covering over 30 products related to fertility, tumors, and chronic disease management [10]. Health Management Innovation - The i99 intelligent health management system offers personalized health management solutions, transitioning the business focus from "treatment" to "prevention" [11]. - This system integrates various health assessments and aims to redefine health management services, potentially opening new revenue streams for the company [11]. Industry Challenges and Opportunities - The IVD industry in China is undergoing a significant reduction in the number of companies, indicating a rapid increase in industry concentration [3]. - Despite challenges, AI healthcare is receiving policy support, reshaping industry paradigms [4].

Group 1: Business Performance and Financials - In the first half of 2025, the company recorded a credit impairment loss of 116 million yuan due to extended payment cycles and decreased payment capabilities of some clients [6] - The company has established a specialized accounts receivable management team to improve cash flow and reduce future impairment risks [6] - The company aims to narrow the credit impairment provision ratio back to normal industry levels as client payment efficiency improves [6] Group 2: Cancer Screening and Diagnostics - The company has completed over 2.35 million fecal DNA methylation tests for colorectal cancer screening [8] - The company is expanding its screening services to include gastric cancer, liver cancer, and endometrial cancer, with plans for regulatory approval [8] - The company is developing non-invasive screening technologies that assess ctDNA status and dynamic changes, enhancing clinical applications [16] Group 3: Consumer Health Products - The company has launched over 30 consumer health products, focusing on fertility and chronic disease management, allowing customers to perform home tests [4] - The i99 Smart Health System offers a comprehensive health management model, integrating precise detection, scientific assessment, and dynamic monitoring [5] - The company is transitioning health management from "passive treatment" to "active prevention" with various health management solutions [4] Group 4: International Expansion - The company secured a 9.5 billion yuan contract for external testing services in Saudi Arabia, marking the largest procurement order to date [12] - The company is collaborating with Thailand's public health department to include non-invasive prenatal testing (NIPT) in government insurance coverage [13] - The company has completed over 100 technology transfer projects in 36 countries, enhancing local healthcare capabilities [14] Group 5: Research and Development - The company is increasing R&D investments in tumor companion diagnostics and aims to respond to regulatory requirements and market demands [3] - The company is focusing on developing products for genetic diseases and chronic conditions, particularly targeting the elderly population [17] - The company has developed the GeneT model for genetic testing, significantly improving analysis efficiency and accuracy [17]