来源：新浪证券-红岸工作室 11月18日，君实生物跌1.76%，成交额2.74亿元，换手率0.95%，总市值383.98亿元。 异动分析 创新药+生物疫苗+猴痘概念 1、2024年年报，公司具备完整的从创新药物的发现和开发、 在全球范围内的临床研究、 大规模生产到 商业化的全产业链能力， 旨在成为立足中国、 布局全球的创新医药公司。 公司坚持质量为本、 求真务 实、 诚信合规、 追求卓越的企业价值观， 致力于通过源头创新以及合作开发等形式来研发 first-in-class （同类首创）或 best-in-class（同类最优） 的药物。 通过卓越的创新药物发现能力、 强大的生物技术研 发能力和大规模生产能力， 公司已成功开发出极具市场潜力的药品组合， 多项产品具有里程碑意义： 核心产品之一特瑞普利单抗是国内首个获得 NMPA 批准上市的国产抗 PD-1 单克隆抗体， 截至本报告 披露日已在中国内地获批 11 项适应症， 另有一项 sNDA 已受理， 其中多项为公司独家或领先适应 症， 特瑞普利单抗还是 FDA 批准上市的首个中国自主研发和生产的创新生物药， 截至本报告披露日， 特瑞普利单抗已在中国内地、 中 ...

Core Viewpoint - Junshi Biosciences is positioned as a comprehensive innovative pharmaceutical company with capabilities spanning drug discovery, clinical research, large-scale production, and commercialization, aiming for a global footprint while being rooted in China [2] Group 1: Company Overview - Junshi Biosciences has developed a strong portfolio of innovative drugs, including the first domestically approved PD-1 monoclonal antibody, Toripalimab, which has received 11 indications in mainland China and is also approved in multiple countries including the US and EU [2] - The company is actively engaged in the development of early-stage products, with several expected to enter critical registration clinical trials by 2025 [2] - The company’s revenue composition includes 90.67% from drug sales, 8.74% from technology licensing, and 0.59% from technical services [7] Group 2: Recent Developments - Junshi Biosciences is collaborating with various research institutions and universities to develop vaccines, including those for monkeypox and Zika, which are currently in preclinical development [3] - A partnership has been established with Peking University and other institutions to jointly develop a recombinant protein vaccine for monkeypox [3] Group 3: Financial Performance - For the period from January to September 2025, Junshi Biosciences reported revenue of 1.806 billion yuan, reflecting a year-on-year growth of 42.06%, while the net profit attributable to the parent company was -596 million yuan, a 35.72% increase year-on-year [8] - As of September 30, 2025, the number of shareholders increased by 15.17% to 35,900, while the average circulating shares per person decreased by 12.96% [8] Group 4: Market Activity - On November 13, Junshi Biosciences' stock rose by 2.38%, with a trading volume of 341 million yuan and a turnover rate of 1.14%, bringing the total market capitalization to 40.246 billion yuan [1] - The stock has seen a net inflow of 34.14 million yuan from major investors, indicating a slight increase in institutional interest [4][5]

Core Viewpoint - The company, Junshi Biosciences, aims to establish itself as a global innovative pharmaceutical company with a complete industry chain capability from drug discovery to commercialization, focusing on quality and innovation in drug development [2][3]. Company Overview - Junshi Biosciences was founded on December 27, 2012, and went public on July 15, 2020. Its main business involves the research and commercialization of monoclonal antibody drugs and other therapeutic proteins, with 90.67% of revenue coming from drug sales [7]. - As of September 30, 2025, the company reported a revenue of 1.806 billion yuan, a year-on-year increase of 42.06%, while the net profit attributable to shareholders was -596 million yuan, a year-on-year increase of 35.72% [8]. Product Development - The company has developed a strong portfolio of innovative drugs, including the first domestically approved PD-1 monoclonal antibody, Toripalimab, which has received approval for 11 indications in mainland China and is also approved in multiple countries including the US and EU [2]. - Junshi Biosciences is also advancing its pipeline with Tifcemalimab, the first anti-BTLA monoclonal antibody entering clinical development, currently undergoing two Phase III trials [2]. Collaborations and Research - The company is collaborating with institutions such as Peking University and the Chinese Academy of Sciences to develop vaccines, including a monkeypox vaccine, which is currently in the preclinical development stage [3][8]. Market Performance - On November 7, the company's stock fell by 1.92%, with a trading volume of 292 million yuan and a market capitalization of 38.799 billion yuan [1]. - The stock has seen a net outflow of 458.376 million yuan from major investors, indicating a trend of reduced holdings over the past three days [4][5]. Technical Analysis - The average trading cost of the stock is 41.33 yuan, with the current price approaching a resistance level of 38.99 yuan, suggesting potential volatility in the near term [6].

Core Viewpoint - Junshi Biosciences is positioned as a comprehensive innovative pharmaceutical company with capabilities spanning drug discovery, clinical research, large-scale production, and commercialization, aiming for a global footprint while being rooted in China [2] Group 1: Company Overview - Junshi Biosciences was established on December 27, 2012, and went public on July 15, 2020, focusing on the research and commercialization of monoclonal antibody drugs and other therapeutic proteins [7] - The company's main revenue sources include drug sales (90.67%), technology licensing and royalties (8.74%), and technical services (0.59%) [7] - As of September 30, 2025, Junshi Biosciences reported a revenue of 1.806 billion yuan, a year-on-year increase of 42.06%, while the net profit attributable to shareholders was -596 million yuan, reflecting a year-on-year growth of 35.72% [8] Group 2: Product Development and Pipeline - The company has developed a robust product pipeline, including its core product, Toripalimab, which is the first domestically approved PD-1 monoclonal antibody in China, with 11 approved indications and one supplemental NDA under review [2] - Toripalimab is also the first innovative biologic drug developed and produced in China to receive FDA approval, with approvals in multiple regions including the EU, the UK, and Australia [2] - Junshi Biosciences is advancing its self-developed Tifcemalimab, the first anti-BTLA monoclonal antibody to enter clinical development, with two Phase III registration trials ongoing [2] Group 3: Collaborations and Future Prospects - The company is collaborating with institutions such as Peking University and the Chinese Academy of Sciences to develop vaccines, including a monkeypox vaccine, which is currently in preclinical development [3] - Junshi Biosciences aims to explore early-stage pipelines, with multiple products expected to initiate critical registration clinical trials by 2025 [2]

Core Viewpoint - Junshi Biosciences has demonstrated significant growth potential in the innovative drug and biopharmaceutical sectors, with a focus on developing first-in-class and best-in-class therapies, particularly in oncology and vaccine development [2][3]. Group 1: Company Overview - Junshi Biosciences is a Shanghai-based biopharmaceutical company established on December 27, 2012, and listed on July 15, 2020, specializing in monoclonal antibody drugs and therapeutic protein drug development [7]. - The company's main revenue sources include drug sales (90.67%), technology licensing (8.74%), and technical services (0.59%) [7]. - As of September 30, 2023, Junshi Biosciences reported a revenue of 1.806 billion yuan, a year-on-year increase of 42.06%, while the net profit attributable to shareholders was -596 million yuan, reflecting a year-on-year growth of 35.72% [8]. Group 2: Product Development and Pipeline - The company has a comprehensive capability in the entire industry chain from drug discovery to commercialization, aiming to establish a global presence [2]. - Core product Toripalimab is the first domestically approved PD-1 monoclonal antibody in China, with 11 approved indications and additional applications under review [2]. - The company is also developing Tifcemalimab, the first anti-BTLA monoclonal antibody to enter clinical development, with ongoing Phase III trials and multiple combination studies [2]. Group 3: Collaborations and Vaccine Development - Junshi Biosciences is collaborating with institutions such as Peking University and the Chinese Academy of Sciences to develop vaccines, including a monkeypox recombinant protein vaccine, currently in preclinical development [3]. - The company holds a pipeline of vaccine-related products, including those for monkeypox and Zika virus, through partnerships with research institutions and universities [3].

Core Viewpoint - Junshi Biosciences (01877) shares rose over 6%, currently up 6.34% at HKD 31.54, with a trading volume of HKD 182 million [1] Group 1: Upcoming Conference - The European Society for Medical Oncology (ESMO) annual meeting will be held in Berlin, Germany from October 17 to October 21, 2025 [1] - Junshi Biosciences will present over 20 studies on its innovative products, including anti-PD-1 monoclonal antibody Toripalimab, anti-BTLA monoclonal antibody Tifcemalimab, and selective PI3K-α inhibitor JS105 at the conference [1] Group 2: Research Highlights - The conference's latest breakthrough abstracts (Late-Breaking Abstracts, LBA) have been announced, with two studies on Toripalimab selected for oral presentations [1] - One of the studies on Toripalimab has been chosen for the prestigious Proffered Paper session, showcasing cutting-edge advancements in combination therapy [1]

Core Viewpoint - Junshi Biosciences (01877) shares rose over 6%, currently up 6.34% at HKD 31.54, with a trading volume of HKD 1.82 billion [1] Group 1: Upcoming Conference - The European Society for Medical Oncology (ESMO) annual meeting will take place from October 17 to October 21, 2025, in Berlin, Germany [1] - Junshi Biosciences will present over 20 studies on its innovative products, including anti-PD-1 monoclonal antibody Toripalimab, anti-BTLA monoclonal antibody Tifcemalimab, and selective PI3K-α inhibitor JS105 at the conference [1] Group 2: Research Highlights - The conference's latest breakthrough abstracts (Late-Breaking Abstracts, LBA) have been announced, with two studies on Toripalimab selected for oral presentations [1] - One of the studies has been honored with a spot in the prestigious Proffered Paper session, showcasing advancements in Toripalimab combination therapy [1]

Core Viewpoint - Junshi Biosciences aims to establish itself as a global innovative pharmaceutical company with a complete industry chain capability from drug discovery to commercialization, focusing on quality and innovation [2][3]. Company Overview - Junshi Biosciences, founded on December 27, 2012, and listed on July 15, 2020, specializes in the research and commercialization of monoclonal antibody drugs and other therapeutic proteins [7]. - The company's main revenue sources include drug sales (90.67%), technology licensing (8.74%), and other services (0.59%) [7]. Product Development - The company has developed a promising drug portfolio, including its core product, Toripalimab, which is the first domestically approved PD-1 monoclonal antibody in China, with 11 approved indications and one supplemental NDA under review [2]. - Toripalimab is also the first innovative biopharmaceutical developed and produced in China to receive FDA approval, with approvals in multiple regions including the U.S., EU, and Australia [2]. - Junshi's self-developed Tifcemalimab is the first anti-tumor anti-BTLA monoclonal antibody to enter clinical development, currently undergoing two Phase III trials [2]. Vaccine Development - Junshi's subsidiary, JunTuo Biotech, is developing vaccine-related products, including monkeypox and Zika vaccines, which are currently in preclinical development [3]. - The company has partnered with several institutions, including Peking University and the Chinese Academy of Sciences, to jointly develop a recombinant protein vaccine for monkeypox [3]. Financial Performance - For the first half of 2025, Junshi Biosciences reported revenue of 1.168 billion yuan, a year-on-year increase of 48.64%, while the net profit attributable to shareholders was -413 million yuan, a 36.01% increase [8]. - As of June 30, 2025, the number of shareholders increased by 5.88% to 31,200, with a decrease in average circulating shares per person by 5.56% [8]. Market Activity - On September 24, Junshi Biosciences' stock rose by 0.22%, with a trading volume of 621 million yuan and a turnover rate of 1.95%, bringing the total market capitalization to 42.782 billion yuan [1]. - The stock has seen a net outflow of 27.407 million yuan from major funds, indicating a lack of strong buying interest [4][5].

Core Viewpoint - Junshi Biosciences is positioned as a comprehensive innovative pharmaceutical company with capabilities spanning drug discovery, clinical research, large-scale production, and commercialization, aiming for a global footprint while being rooted in China [2] Group 1: Company Overview - Junshi Biosciences was established on December 27, 2012, and went public on July 15, 2020, focusing on the research and commercialization of monoclonal antibodies and therapeutic proteins [7] - The company's main revenue sources include 90.67% from drug sales, 8.74% from technology licensing, and 0.59% from technical services [7] - As of June 30, 2025, Junshi Biosciences reported a revenue of 1.168 billion yuan, a year-on-year increase of 48.64%, while the net profit attributable to shareholders was -413 million yuan, a year-on-year increase of 36.01% [8] Group 2: Product Pipeline and Innovations - The company has developed a significant product portfolio, including the first domestically approved PD-1 monoclonal antibody, Toripalimab, which has received approval for 11 indications in mainland China and is also approved in multiple countries including the US and EU [2] - Junshi Biosciences is advancing its pipeline with Tifcemalimab, the first anti-BTLA monoclonal antibody entering clinical development, currently undergoing two Phase III trials [2] - The company is also collaborating with various research institutions to develop vaccines, including monkeypox and Zika vaccines, which are currently in preclinical development [3] Group 3: Market Performance and Investor Sentiment - On September 23, Junshi Biosciences' stock fell by 4.26%, with a trading volume of 755 million yuan and a market capitalization of 42.69 billion yuan [1] - The stock has seen a net outflow of 48.4 million yuan from major investors, indicating a trend of reduced holdings over the past three days [4][5] - The average trading cost of the stock is 41.93 yuan, with the stock price approaching a resistance level of 42.00 yuan, suggesting potential volatility [6]

Core Viewpoint - Junshi Biosciences aims to establish itself as a global innovative pharmaceutical company with a complete industry chain capability from drug discovery to commercialization, focusing on quality and innovation [2][3]. Company Overview - Junshi Biosciences, founded on December 27, 2012, and listed on July 15, 2020, specializes in the research and commercialization of monoclonal antibody drugs and other therapeutic proteins [7]. - The company's main revenue sources include drug sales (90.67%), technology licensing (8.74%), and other services (0.59%) [7]. Product Development - The company has developed a promising drug portfolio, including its core product, Toripalimab, which is the first domestically approved PD-1 monoclonal antibody in China, with 11 approved indications and one supplemental NDA under review [2]. - Toripalimab is also the first innovative biologic drug developed and produced in China to receive FDA approval, with approvals in multiple regions including the U.S., EU, and Australia [2]. - Junshi is advancing its pipeline with Tifcemalimab, the first anti-BTLA monoclonal antibody entering clinical development, currently undergoing two Phase III trials [2]. Vaccine Development - The company is collaborating with various research institutions to develop vaccines, including monkeypox and Zika vaccines, which are currently in preclinical development [3]. - A partnership with Peking University and other institutions has been established to jointly develop a recombinant protein vaccine for monkeypox [3]. Financial Performance - For the first half of 2025, Junshi Biosciences reported revenue of 1.168 billion yuan, a year-on-year increase of 48.64%, while the net profit attributable to shareholders was -413 million yuan, reflecting a 36.01% increase [8]. - As of June 30, 2025, the number of shareholders increased by 5.88% to 31,200, with a decrease in average circulating shares per person by 5.56% [8]. Market Activity - On September 18, the stock price of Junshi Biosciences increased by 0.20%, with a trading volume of 909 million yuan and a turnover rate of 2.57%, resulting in a total market capitalization of 46.951 billion yuan [1]. - Recent trading activity indicates a net outflow of 31.6178 million yuan from main funds, with a lack of clear trends in main fund movements [4][5].