Core Viewpoint - The company Shijiazhuang Pharmaceutical Group (stock code: 02005) has received approval from the National Medical Products Administration of China for its indocyanine green to be used as an active pharmaceutical ingredient in marketed formulations [1] Group 1 - Indocyanine green is utilized for diagnosing various liver diseases, including cirrhosis, liver fibrosis, and drug-induced liver injury, as well as assessing liver damage and reserve function [1] - The compound is also applicable for choroidal vascular angiography to identify the location of choroidal disorders [1]

智通财经APP讯，石四药集团(02005)公布，该集团的吲哚菁绿已获中国国家药品监督管理局批准登记成 为在上市制剂使用的原料药。 吲哚菁绿可用于诊断肝硬化、肝纤维化、韧性肝炎、职业和药物中毒性肝病等各种肝脏疾病，了解肝脏 的损害程度及其储备功能; 亦可用于脉络膜血管造影，确定脉络膜疾患的位置。 ...

格隆汇9月9日丨石四药集团(02005.HK)公告，集团的吲哚菁绿已获中国国家药品监督管理局批准登记成 为在上市制剂使用的原料药。吲哚菁绿可用于诊断肝硬化、肝纤维化、韧性肝炎、职业和药物中毒性肝 病等各种肝脏疾病，了解肝脏的损害程度及其储备功能;亦可用于脉络膜血管造影，确定脉络膜疾患的 位置。 ...

香港交易及結算所有限公司及香港聯合交易所有限公司對本公告之內容概不負責，對其準確 性或完整性亦不發表任何聲明，並明確表示，概不會就因本公告全部或任何部份內容而產生 或因倚賴該等內容而引致之任何損失承擔任何責任。 吲哚菁綠可用於診斷肝硬化、肝纖維化、韌性肝炎、職業和藥物中毒性肝病等各種肝臟疾病， 瞭解肝臟的損害程度及其儲備功能; 亦可用於脈絡膜血管造影，確定脈絡膜疾患的位置。 本公告為本公司自願發佈，目的是使股東及潛在投資者瞭解本集團最新業務發展情況。 承董事局命 執行董事兼公司秘書 周興揚 香港，二零二五年九月九日 自願公告 產品開發的最新進展 石四藥集團有限公司（「本公司」，連同其附屬公司，「本集團」）董事局（「董事局」）欣然公告， 本集團的吲哚菁綠已獲中國國家藥品監督管理局批准登記成為在上市製劑使用的原料藥。 於本公告日期，董事局成員包括執行董事曲繼廣先生、蘇學軍先生、孟國先生、周興揚先生及 曲婉蓉女士，非執行董事劉文軍先生，以及獨立非執行董事王亦兵先生、周國偉先生及姜廣策 先生。 ...

Core Viewpoint - The executive director, chairman, and CEO of China Pharmaceutical (石四药集团) increased his shareholding by acquiring 440,000 shares at an average price of HKD 3.2797 per share, totaling approximately HKD 1.4431 million, resulting in a slight increase in his ownership percentage from 39.70% to 39.72% [1][2]. Group 1 - The executive director and CEO, 曲继广, purchased 440,000 shares of China Pharmaceutical on September 8, 2025 [1][3]. - The total investment for the share purchase was about HKD 1.4431 million [1]. - Following the acquisition, 曲继广's total shareholding reached 1,172,182,000 shares [1][2].

Group 1 - The latest shareholder equity disclosure for Stone Four Pharmaceutical Group (02005) and BYD Electronic (00285) was conducted on September 8, 2025 [1] Group 2 - For Stone Four Pharmaceutical Group (02005), China Pharmaceutical Company Limited increased its holdings from 878 million shares to 881 million shares, representing a holding percentage change from 29.77% to 29.83% [2] - Qu Jiguang also increased his holdings in Stone Four Pharmaceutical Group from 1.17 billion shares to 1.172 billion shares, maintaining a holding percentage of 39.70% [2] - For BYD Electronic (00285), Jiang Xiangrong increased his holdings from 262,000 shares to 270,000 shares, with a holding percentage remaining at 0.01% [2]

Group 1 - The core point of the news is that Qu Jiguang, the Executive Director, Chairman, and CEO of Stone Four Pharmaceutical Group, increased his shareholding by purchasing 1.88 million shares at an average price of HKD 3.0859 per share, totaling approximately HKD 5.8015 million [1] - Following this transaction, Qu Jiguang's total shareholding increased to 1,171,742,000 shares, raising his ownership percentage from 39.64% to 39.70% [1][2] Group 2 - The transaction occurred on September 5, 2025, and was disclosed in the latest equity disclosure documents from the Hong Kong Stock Exchange [1] - The average price per share for the purchase was HKD 3.0859, indicating a strategic investment by the executive [2]

Core Viewpoint - The company Shijiazhuang Pharmaceutical Group has received production registration approvals from the National Medical Products Administration for seven pharmaceutical products, indicating a significant advancement in its product portfolio and market positioning [1]. Group 1: Product Approvals - The company has obtained approvals for the following products: 1. Arginine Perindopril Tablets (10mg), classified as a Class 4 chemical drug, is the second domestic company to receive approval, primarily used for treating hypertension and congestive heart failure [1]. 2. Progesterone Injection (II) (1.112ml:25mg), classified as a Class 3 chemical drug, is used for progesterone supplementation in assisted reproductive technology (ART) [1]. 3. Labetalol Hydrochloride Injection (20ml:100mg), classified as a Class 3 chemical drug, is used for various types of hypertension, especially hypertensive crises, and for blood pressure control before surgery [1]. 4. Calcium Chloride Injection (10ml:1g), classified as a Class 3 chemical drug, is primarily used for treating acute hypocalcemia and magnesium poisoning [1]. 5. Compound Electrolyte Acetate Injection (500ml), classified as a Class 3 chemical drug, is used for treating isotonic dehydration with mild acidosis and for replenishing extracellular fluid and blood volume loss [1]. 6. Compound Electrolyte Injection (V) (500ml), classified as a Class 3 chemical drug, serves as a source of water and electrolytes for adults [1]. 7. Levosalbutamol Hydrochloride Nebulization Solution (3ml:0.63mg), classified as a Class 3 chemical drug, is used for treating or preventing bronchospasm in adults and children over six years old with reversible airway obstructive diseases [1].

Core Viewpoint - The company, Stone Four Pharmaceutical Group, has received production registration approvals from the National Medical Products Administration for seven pharmaceutical products, indicating a significant advancement in its product portfolio and market positioning [1]. Group 1: Product Approvals - The company has obtained approval for Arginine Perindopril Tablets (10mg), classified as a Class 4 chemical drug, making it the second domestic company to receive this approval. This product is primarily used for treating hypertension and congestive heart failure [1]. - The company has also received approval for Progesterone Injection (II) (1.112ml: 25mg), classified as a Class 3 chemical drug, which is used for progesterone supplementation in assisted reproductive technology (ART) [1]. - Approval has been granted for Labetalol Hydrochloride Injection (20ml: 100mg), also a Class 3 chemical drug, used for various types of hypertension, especially hypertensive crises, and for blood pressure control before surgery [1]. - Calcium Chloride Injection (10ml: 1g), classified as a Class 3 chemical drug, is approved for treating acute hypocalcemia and magnesium poisoning [1]. - The company has received approval for Compound Electrolyte Acetate Sodium Injection (500ml), a Class 3 chemical drug, used for treating isotonic dehydration with mild acidosis [1]. - Approval has been granted for Compound Electrolyte Injection (V) (500ml), classified as a Class 3 chemical drug, which serves as a source of water and electrolytes for adults [1]. - The company has also received approval for Levosalbutamol Hydrochloride Nebulization Solution (3ml: 0.63mg), a Class 3 chemical drug, used for treating or preventing bronchospasm in adults and children over six years old with reversible airway obstructive diseases [1].

Core Viewpoint - The company, Shijiazhuang Pharmaceutical Group, has received production registration approvals from the National Medical Products Administration for seven pharmaceutical products, indicating a significant advancement in its product portfolio and market positioning [1]. Group 1: Product Approvals - The company has obtained approvals for the following seven drugs: 1. Arginine Perindopril Tablets (10mg), classified as a Class 4 chemical drug, is the second domestic company to receive approval, primarily used for treating hypertension and congestive heart failure [1]. 2. Progesterone Injection (II) (1.112ml: 25mg), classified as a Class 3 chemical drug, is used for progesterone supplementation in assisted reproductive technology (ART) [1]. 3. Labetalol Hydrochloride Injection (20ml: 100mg), classified as a Class 3 chemical drug, is indicated for various types of hypertension, especially hypertensive crises, and for blood pressure control before surgery [1]. 4. Calcium Chloride Injection (10ml: 1g), classified as a Class 3 chemical drug, is primarily used for treating acute hypocalcemia and magnesium poisoning [1]. 5. Compound Electrolyte Acetate Injection (500ml), classified as a Class 3 chemical drug, is used for treating isotonic dehydration with mild acidosis and for replenishing extracellular fluid and blood volume loss [1]. 6. Compound Electrolyte Injection (V) (500ml), classified as a Class 3 chemical drug, serves as a source of water and electrolytes for adults [1]. 7. Levosalbutamol Nebulization Solution (3ml: 0.63mg), classified as a Class 3 chemical drug, is used for treating or preventing bronchospasm in adults and children over 6 years old with reversible airway obstructive diseases [1].