Core Viewpoint - The Hong Kong pharmaceutical stocks continue to decline, particularly in the CRO sector, with significant drops in share prices for several companies [1] Group 1: Company Performance - Junshi Biosciences (01877.HK) decreased by 7.98%, trading at 27.22 HKD [1] - Kanglong Chemical (03759.HK) fell by 6.3%, with a price of 24.4 HKD [1] - Kelun Pharmaceutical (06821.HK) saw a decline of 5.69%, priced at 91.95 HKD [1] - Tigermed (03347.HK) dropped by 3.48%, trading at 42.4 HKD [1]

Group 1 - Pharmaceutical stocks continue to decline, with CRO sector leading the drop, including significant declines in Junshi Biosciences (down 7.98%), Kanglong Chemical (down 6.3%), Kelaiying (down 5.69%), and Tigermed (down 3.48%) [1] - Recent market trends in the pharmaceutical sector are attributed to several factors, including a deal between the Trump administration and Pfizer to lower drug prices in the U.S., which is seen as a reconciliation signal between U.S. pharmaceutical companies and the government [1] - The U.S. Senate's consideration of a bill to prohibit certain Chinese biotech companies from receiving federal funding has led to a significant pullback in the CXO sector [1] Group 2 - Recent tensions in U.S.-China trade relations have escalated, with a renewed tariff war expected; however, the pharmaceutical market is not overly concerned as the industry has shown resilience since the first tariff war in April [2] - The innovative drug and CXO sectors have outperformed other sub-industries, driven by China's rising independent innovation and ongoing overseas business development, which are less affected by tariffs [2] - The CXO sector benefits from strong upstream and downstream relationships and a service pricing model that allows companies to pass on tariff pressures relatively freely [2]

Group 1 - Pharmaceutical stocks continued to decline, with CRO sector leading the drop, including significant declines in companies like Junshi Biosciences (-7.98%), Kanglong Chemical (-6.3%), and others [1] - Recent market trends in the pharmaceutical sector are attributed to several factors, including a deal between the Trump administration and Pfizer to lower drug prices in the U.S., which is seen as a reconciliation signal between U.S. pharmaceutical companies and the government [1] - The U.S. Senate's consideration of a bill to prohibit certain Chinese biotech companies from receiving federal funding has led to a significant pullback in the CXO sector [1] Group 2 - Tensions in U.S.-China trade relations have escalated, with renewed tariff battles expected; however, the pharmaceutical market is not overly concerned as the industry has shown resilience [2] - The innovative drug and CXO sectors have performed exceptionally well since the first tariff battle in April, driven by China's rising independent innovation and ongoing overseas business development [2] - The CXO sector's strong business model allows companies to transfer tariff pressures relatively freely due to strong upstream and downstream relationships [2]

香港交易及結算所有限公司及香港聯合交易所有限公司對本公告的內 容 概 不 負 責，對 其 準 確 性 或 完 整 性 亦 不 發 表 任 何 聲 明，並 明 確 表 示，概 不對因本公告全部或任何部分內容而產生或因倚賴該等內容而引致的 任 何 損 失 承 擔 任 何 責 任。 HANGZHOU TIGERMED COUNSULTING CO., LTD. 本公司董事（「董 事」）會（「董事會」）謹 此 宣 佈，於2025年10月10日，本 公 司、 本 公 司 全 資 子 公 司 嘉 興 欣 格 醫 藥 科 技 有 限 公 司（與 本 公 司 合 稱「賣 方」）與 方 達 醫 藥 技 術（上 海）有 限 公 司（「買 方」）（方 達 控 股 公 司（「方達控股」連 同 其 子 公 司 統 稱「方達集團」）的 全 資 子 公 司）簽 訂 股 份 轉 讓 協 議（「股份轉讓協 議」），據 此，買 方 有 條 件 同 意 收 購，而 賣 方 有 條 件 同 意 出 售 上 海 觀 合 醫 藥 科 技 股 份 有 限 公 司（「目標公司」）的 全 部 已 發 行 股 本，總 代 價 為 人 民 幣 270,000,0 ...

Group 1 - The core point of the article is that Tiger Med (03347) has signed a share transfer agreement to sell all issued shares of Shanghai Guanhao Medical Technology Co., Ltd. to Fangda Pharmaceutical Technology (Shanghai) Co., Ltd. for a total consideration of RMB 270 million [1] - The transaction is expected to enhance the operational efficiency of the group by optimizing resource allocation and integrating internal resources [2] - The target group, which primarily engages in clinical trial services, will remain a subsidiary of the company after the sale, allowing for better coordination of business functions within the overall group structure [1][2] Group 2 - The sale is anticipated to promote synergies within the group by simplifying decision-making processes and achieving centralized management [2] - Tiger Med is recognized as a leading provider of comprehensive biopharmaceutical research and development services in China, with a growing global influence [1] - Fangda Group, the buyer, provides research, analysis, and development services throughout the entire product discovery and development process [1]

公告称，出售事项使集团可透过整合内部资源，优化其资源配置并提升营运效率。由于方达集团亦为集 团子公司，出售事项有助于在集团整体架构内更好地协调业务职能及促进协同效应。透过将目标集团业 务整合至方达集团旗下，集团可实现集中管理并简化决策制定程序，从而提升成本效益与营运专注度。 截至本公告日期，方达控股为公司的子公司，其股份于香港联合交易所有限公司上市(股份代号： 3347)。因此，在完成出售事项后，目标公司以及观合医药(香港)有限公司和无锡观合医学检验所有限公 司(均为目标公司的子公司，连同目标公司统称为"目标集团")将仍作为公司的子公司。 公司是中国领先的综合生物制药研发服务提供商，且全球影响力正在不断扩大，主要从事为国内外创新 药和医疗器械企业提供创新药、医疗器械和生物技术相关产品的一站式专业临床研究服务。目标集团主 要从事临床试验服务。方达集团从事提供贯穿整个产品发现及开发过程中的研究、分析及开发服务。 智通财经APP讯，泰格医药(03347)发布公告，于2025年10月10日，公司、公司全资子公司嘉兴欣格医药 科技有限公司(与公司合称"卖方")与方达医药技术(上海)有限公司("买方")(方达控股公司(" ...

Core Viewpoint - Tiger Medical (03347.HK) announced the conditional sale of all issued shares of Shanghai Guanhua Medical Technology Co., Ltd. for a total consideration of RMB 270 million, which is expected to enhance operational efficiency and resource allocation within the group [1] Group 1: Transaction Details - The sale agreement is between Tiger Medical and its wholly-owned subsidiary, Jiaxing Xinge Medical Technology Co., Ltd., and the buyer is Fangda Pharmaceutical Technology (Shanghai) Co., Ltd., a wholly-owned subsidiary of Fangda Holdings [1] - The total consideration for the transaction is RMB 270 million [1] Group 2: Strategic Implications - The board believes that the sale will allow the group to optimize resource allocation and enhance operational efficiency through internal resource integration [1] - As Fangda Holdings is also a subsidiary of the group, the transaction will facilitate better coordination of business functions and promote synergy within the overall group structure [1] - Integrating the target group's business under Fangda Holdings is expected to achieve centralized management and simplify decision-making processes, thereby improving cost-effectiveness and operational focus [1]

本 公 告 乃 由 杭 州 泰 格 醫 藥 科 技 股 份 有 限 公 司（「本公司」，連 同 其 子 公 司 統 稱「本集團」）自 願 作 出。 香港交易及結算所有限公司及香港聯合交易所有限公司對本公告的內 容 概 不 負 責，對 其 準 確 性 或 完 整 性 亦 不 發 表 任 何 聲 明，並 明 確 表 示，概 不對因本公告全部或任何部分內容而產生或因倚賴該等內容而引致的 任 何 損 失 承 擔 任 何 責 任。 HANGZHOU TIGERMED COUNSULTING CO., LTD. 杭州泰格醫藥科技股份有限公司 （於 中 華 人 民 共 和 國 註 冊 成 立 的 股 份 有 限 公 司） （股 份 代 號：3347） 自願公告 出售目標集團 由 於 出 售 事 項 屬 於 本 集 團 內 部 交 易，預 計 出 售 事 項 不 會 對 本 集 團 的 綜 合 財 務 狀 況 表 產 生 任 何 重 大 影 響。 本 公 司 是 中 國 領 先 的 綜 合 生 物 製 藥 研 發 服 務 提 供 商，且 全 球 影 響 力 正 在 不 斷 擴 大，主 要 從 事 為 國 內 外 創 新 藥 ...

Core Viewpoint - The report highlights the changes in the Hong Kong Stock Connect holdings, indicating which companies have seen the largest increases and decreases in ownership percentages over recent trading days [1][2][3]. Summary by Category Recent Changes in Holdings - GX Hengsheng High Dividend (03110) saw an increase of 0.22% in its Hong Kong Stock Connect holding percentage, bringing it to 2.09% [2] - The largest decrease was observed in Southern Hengsheng Technology (03033), which dropped by 0.31% to 59.93% [2] Five-Day Changes - The most significant increase in holdings over the last five trading days was for Dazhong Public Utilities (01635), which rose by 8.30% to 67.37% [3] - Conversely, Kingsoft Cloud (03896) experienced the largest decrease, falling by 2.65% to 25.92% [3] Twenty-Day Changes - Over the past twenty days, Dazhong Public Utilities (01635) also led with a substantial increase of 34.28%, reaching a holding percentage of 67.37% [4] - The largest decrease was recorded for Yisou Technology (02550), which fell by 13.04% to 33.85% [4]

截至月份: 2025年9月30日 狀態: 新提交 致：香港交易及結算所有限公司 公司名稱: 杭州泰格醫藥科技股份有限公司 呈交日期: 2025年10月8日 I. 法定/註冊股本變動 | 1. 股份分類 | 普通股 | 股份類別 | A | | | 於香港聯交所上市 (註1) | | 否 | | | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | | 證券代號 (如上市) | 300347 | 說明 | | 於深圳證券交易所上市 | | | | | | | | | 法定/註冊股份數目 | | | 面值 | | | 法定/註冊股本 | | | 上月底結存 | | | 737,901,250 | RMB | | 1 | RMB | | 737,901,250 | | 增加 / 減少 (-) | | | 0 | | | | RMB | | 0 | | 本月底結存 | | | 737,901,250 | RMB | | | 1 RMB | | 737,901,250 | | 2. 股份分類 | 普通股 | 股份類別 | H | | 於香港聯交所上市 ...