Summary of Pharmaron (3759.HK) Earnings Review Company Overview - **Company**: Pharmaron (3759.HK) - **Market Cap**: HK$38.5 billion / $4.9 billion - **Industry**: Healthcare Services in China & Korea - **Rating**: Buy - **12-month Price Target**: HK$23.30 (current price: HK$21.68, upside: 7.5%) [1][6] Key Financial Highlights - **2Q25 Revenue**: Rmb3.34 billion, +13.9% year-over-year (y/y) [1] - **Adjusted Net Profit**: Rmb406 million, +15.6% y/y and +16.3% quarter-over-quarter (q/q) [1] - **Adjusted Net Margin**: Improved to 12.2% from 11.3% in 1Q25 [1] - **New Orders Growth**: +10% y/y in 1H25, with CMC services seeing +20% y/y growth [2][19] - **Capex**: Rmb1.15 billion in 1H25, on track to meet FY24 capex levels [2] Segment Performance - **Lab Services Revenue**: Rmb2.04 billion, +15.2% y/y and +9.6% q/q [3] - **CMC Services Revenue**: Rmb697 million, +17.4% y/y, with gross margin (GM) improving to 29.9% [21] - **Clinical Development Services Revenue**: Rmb492 million, +8.9% y/y, GM declined to 12.8% [21] - **Biologics and CGT Revenue**: Rmb113 million, -5.8% y/y, GM diluted to -42.4% [21] Geographic and Customer Analysis - **Revenue by Region**: North America (62% of revenue, +6% y/y), Europe (20%, +34% y/y), China (15%, +18% y/y) [19] - **Top 20 Pharma Clients**: Accounted for 21% of total revenue, +63% y/y [19] Guidance and Expectations - **FY25 Revenue Guidance**: Maintained at +10-15% y/y, with expectations for q/q growth in 2H25 [2] - **Free Cash Flow**: Management expects positive free cash flow for FY25 [2] Valuation and Risks - **Valuation Methodology**: Target prices based on a 3-year exit P/E of 20x and a discount rate of 10.5% [20][22] - **Key Upside Risks**: Accelerated revenue conversion, better-than-expected facilities ramp-up, improved order signing [20][22] - **Downside Risks**: US-China trade tensions, rising labor costs, slowdown in global pharma R&D spending [20][22] Investment Thesis - **Positioning**: Pharmaron is the second-largest pharma CRO/CMO platform in China, with resilient demand and potential margin expansion [23] - **Growth Drivers**: Higher GM for CDMO business, recovery of clinical CRO revenue, and narrowed losses in CGT business [23] Conclusion Pharmaron demonstrates strong financial performance with significant growth in revenue and profit margins, supported by robust demand in its service segments. The company maintains a positive outlook for FY25, with strategic investments and geographic expansion contributing to its growth trajectory. The investment thesis remains favorable, with a Buy rating reflecting confidence in the company's ability to navigate market challenges and capitalize on opportunities.

Summary of the Conference Call for 康龙化成 (Crown Bioscience) Company Overview - 康龙化成 reported a revenue growth of 9.5% year-on-year in the first half of 2025, with new orders increasing by over 10% [2][3] - The company achieved a revenue of 33.42 billion yuan in Q2, representing a 13.9% year-on-year increase, while net profit attributable to shareholders was 3.96 billion yuan, down 55.2% year-on-year [2][3] Financial Performance - Total revenue for the first half of 2025 reached 64.41 billion yuan, a 14.9% increase year-on-year [3] - Adjusted net profit for the same period was 7.56 billion yuan, a 9.5% increase year-on-year [3] - The company expects to maintain a revenue growth target of 10% to 15% for the full year 2025 [4][8] Business Segments Performance Laboratory Services - Laboratory services accounted for 60% of total revenue, growing 15.5% year-on-year, with a gross margin maintained at 44%-45% [2][5][11] - The company participated in 795 global drug discovery projects, with significant growth in new molecular type projects [11][20] CMC (Contract Manufacturing Organization) Services - CMC small molecule CDMO services represented 22% of total revenue, with an 18.2% year-on-year growth and a gross margin of 30.2% [2][12] - The company reported a significant increase in new orders, with a 20% year-on-year growth in new contracts [12][18] Clinical Services - Clinical services accounted for 15% of total revenue, with an 11.4% year-on-year growth and a gross margin of 12.3% [2][13] - The company is managing 1,027 clinical projects, including 89 Phase III trials [13][14] Large Molecule and CGT (Cell and Gene Therapy) Services - Revenue from large molecule and CGT services was 1.13 billion yuan, a 5.8% year-on-year decrease, but a 14.3% increase quarter-on-quarter [15] - The company is involved in 22 different development stage CG products, including commercial projects [15] Market Dynamics - The company reported strong growth in MNC (Multinational Corporation) revenue, which increased by 48% [4][16] - The overseas market is showing signs of recovery, while the domestic market is improving but not fully recovered [4][21] Technological Advancements - 康龙化成 is enhancing its AI capabilities by acquiring a controlling stake in 海兴智慧 and establishing a joint R&D center with Zhejiang University [7][23] - The company is integrating AI technology into clinical data management to improve service efficiency [7][14] Sustainability Initiatives - The company has achieved an MSCI ESG rating of AA and is actively pursuing energy-saving and emission reduction strategies [9][10] Future Outlook - 康龙化成 expects to achieve positive free cash flow for the second consecutive year in 2025 [4][8] - The company is optimistic about maintaining strong growth in laboratory services and CMC projects in the second half of the year [22][24] Key Takeaways - 康龙化成 is positioned for continued growth with a focus on expanding its service offerings and leveraging new technologies [24] - The company is committed to sustainability and improving its market position through innovative solutions and strategic partnerships [9][10][24]

Core Viewpoint - 康龙化成's 2025 mid-year report shows a mixed performance with a revenue increase but a significant decline in net profit, raising concerns about its financial health and cash flow management [1][4]. Financial Performance - Total revenue for the first half of 2025 reached 6.441 billion yuan, a year-on-year increase of 14.93% [1]. - Net profit attributable to shareholders was 701 million yuan, down 37.0% compared to the previous year [1]. - In Q2 2025, total revenue was 3.342 billion yuan, up 13.92% year-on-year, while net profit dropped 55.17% to 396 million yuan [1]. - Gross margin improved to 33.97%, an increase of 1.74% year-on-year, but net margin fell to 10.13%, a decrease of 47.56% [1]. - Total expenses (selling, administrative, and financial) amounted to 1.061 billion yuan, accounting for 16.47% of revenue, down 7.08% year-on-year [1]. Cash Flow and Debt Management - The company reported a significant increase in accounts receivable, which reached 2.545 billion yuan, representing 141.9% of the latest annual net profit [1][4]. - Cash and cash equivalents decreased by 45.78% to 1.302 billion yuan [1]. - The company’s short-term borrowings increased by 31.03% due to new borrowings during the reporting period [3]. Investment and Market Position - The company’s return on invested capital (ROIC) was 8.74%, indicating average capital returns, with a historical median ROIC of 11.67% since its listing [3][4]. - Analysts expect the company's performance in 2025 to reach 1.728 billion yuan, with an average earnings per share of 0.97 yuan [4]. Market Trends and Competitor Analysis - The top 20 multinational pharmaceutical companies (MNCs) experienced a growth rate of 48%, driven by mature CMC project pipelines and deeper collaborations in laboratory services [6].

两融数据显示，该股最新融资余额为14.48亿元，近5日增加2384.00万元，增幅为1.67%。（数据宝） 8月22日康龙化成大宗交易一览 | 成交量 | 成交金额 | 成交价 | 相对当日收盘折 | | | | --- | --- | --- | --- | --- | --- | | （万 | （万元） | 格 | 溢价（%） | 买方营业部 | 卖方营业部 | | 股） | | （元） | | | | | 159.97 | 4776.67 | 29.86 | -0.80 | 机构专用 | 中信证券华南股份有限公司 广州万博证券营业部 | | 7.00 | 210.70 | 30.10 | 0.00 | 华泰证券股份有限 | 中信证券股份有限公司上海 | | | | | | 公司泰州分公司 | 分公司 | （文章来源：证券时报网） 康龙化成8月22日大宗交易平台共发生2笔成交，合计成交量166.97万股，成交金额4987.37万元。以折溢 价进行统计，今日有1笔为折价交易，折价率最高达0.80%。从参与大宗交易营业部来看，机构专用席 位共出现在1笔成交的买方或卖方营业部中，合计成交金额为4776.67万元 ...

Core Viewpoint - Kanglong Chemical achieved significant growth in revenue and non-net profit in the first half of the year, despite a decrease in net profit due to a one-time gain from a previous equity transfer [1][2][4] Financial Performance - In the first half of the year, Kanglong Chemical reported revenue of 6.441 billion yuan, a year-on-year increase of 14.93%, and a non-net profit of 637 million yuan, up 36.66% year-on-year [1] - The company's net profit attributable to shareholders was 701 million yuan, a decrease of 37% year-on-year, primarily due to a large equity transfer gain in the same period last year [1] - Revenue for Q1 and Q2 of this year was 3.099 billion yuan and 3.342 billion yuan, respectively, with non-net profits of 292 million yuan and 345 million yuan, both showing positive growth [1] Historical Context - Kanglong Chemical's average quarterly revenue over the past 22 quarters is approximately 2.4135 billion yuan, with an average non-net profit of about 310 million yuan, indicating current performance is significantly above historical averages [4] - The company has consistently generated over 3 billion yuan in quarterly revenue for four consecutive quarters, suggesting a recovery towards historical best performance [2] Market Position - As of August 22, Kanglong Chemical's A-shares closed at 30.1 yuan per share, with a market capitalization of 53.524 billion yuan, while H-shares closed at 21.68 HKD per share, with a market capitalization of 38.394 billion HKD [5] - The company is one of the leading players in the domestic pharmaceutical outsourcing industry, which has experienced fluctuations in performance over the past five years [5] Business Segments - Kanglong Chemical's main business includes laboratory services, small molecule process development, clinical research services, and large molecule and cell and gene therapy services, with the latter being a focus since 2019 [8] - As of mid-2025, the large molecule and cell and gene therapy segment generated revenue of 211 million yuan, with a year-on-year growth of 0.13%, but a negative gross margin of -54.71% [8] Industry Trends - The domestic pharmaceutical outsourcing industry is showing signs of recovery, with leading companies like WuXi AppTec reporting significant revenue growth [9] - Kanglong Chemical's revenue from North American clients was 4.073 billion yuan, a year-on-year increase of 11.02%, accounting for 63.23% of total revenue [9] - The global pharmaceutical investment landscape is recovering, with projections indicating a rise in investment scale from 71 billion USD in 2023 to 102 billion USD in 2024 [10]

Summary of Key Points Core Viewpoint - Kanglong Chemical experienced a slight increase in stock price, closing at 30.10 yuan, with significant trading activity noted in the form of two block trades totaling approximately 4.99 million yuan [1]. Trading Activity - The first block trade occurred at a price of 30.10 yuan for 70,000 shares, amounting to 2.11 million yuan, with a premium rate of 0.00%. The buyer was Huatai Securities, and the seller was CITIC Securities [1]. - The second block trade was executed at a price of 29.86 yuan for 1.60 million shares, totaling 47.77 million yuan, with a premium rate of -0.80%. The buyer was an institutional entity, and the seller was CITIC Securities' South China branch [1]. - Over the past three months, Kanglong Chemical has recorded three block trades with a cumulative transaction value of 73.91 million yuan [1]. Stock Performance - In the last five trading days, the stock has seen a cumulative decline of 0.43%, with a net outflow of 260 million yuan in principal funds [1].

Core Viewpoint - 康龙化成 reported a strong performance in the first half of 2025, with a revenue increase of 14.9% year-on-year, driven by significant growth in orders and robust demand from top pharmaceutical clients [1][4]. Financial Performance - The company achieved a revenue of 6.441 billion yuan in the first half of 2025, reflecting a year-on-year growth of 14.9% [4]. - The net profit attributable to shareholders was 701 million yuan, a decrease of 37.0% year-on-year, primarily due to last year's substantial gains from the disposal of PROTEOLOGIX, INC. shares [4]. - Adjusted net profit under non-IFRS standards was 756 million yuan, representing a year-on-year increase of 9.5% [4]. - New orders signed in the first half of 2025 increased by over 10% year-on-year [4]. Client and Market Dynamics - Revenue from MNC (Top 20 pharmaceutical companies) clients grew significantly by 48.0% year-on-year, attributed to the maturity of CMC project pipelines and deepened collaboration in laboratory services [2][4][9]. - The company added over 480 new clients, with active clients exceeding 2,600 [4]. Strategic Development - 康龙化成 is committed to its long-term development strategy, having established 21 R&D centers and production bases globally, including in China, the UK, and the US [5]. - The company has a workforce of 22,908 employees, with over 1,700 based overseas, and more than 90% of employees engaged in R&D, production, and clinical services [5]. Business Segment Performance - Laboratory services generated revenue of 3.89 billion yuan, up 15.5% year-on-year, with a gross margin of 45.2% [6]. - CMC (small molecule CDMO) services achieved revenue of 1.39 billion yuan, reflecting an 18.2% increase year-on-year, with a gross margin of 30.5% [6]. - Clinical research services reported revenue of 940 million yuan, a year-on-year growth of 11.4% [7]. - Revenue from large molecule and cell & gene therapy services was 210 million yuan, showing a slight increase of 0.1% [8]. Technological and Operational Advancements - The company is enhancing its AI capabilities by integrating clinical data resources with AI technology, aiming to improve service efficiency [6]. - Continuous investments in various technologies, including continuous flow technology and high-throughput experimentation, are being made to support the CMC service segment [11]. Industry Outlook - The company perceives good resilience in overseas client demand, while domestic client demand is expected to gradually recover [3][12].

Investment Rating - The report assigns a "Buy" rating for Kanglong Chemical (300759) based on its performance and growth potential [13]. Core Views - The overall performance of the company shows steady growth, with laboratory services and CMC services contributing significantly to revenue increases [2][3]. - The company maintains a full-year revenue growth guidance of 10-15% for 2025, supported by stable new order growth across its four main business segments [3]. Summary by Sections Financial Performance - In H1 2025, the company achieved revenue of 6.441 billion yuan, a year-on-year increase of 14.9%, and a net profit attributable to shareholders of 700 million yuan, a decline of 37.0% [1]. - The adjusted net profit attributable to shareholders was 756 million yuan, up 9.5% year-on-year, with operating cash flow increasing by 28.06% to 1.408 billion yuan [1]. Business Segments - **Laboratory Services**: Revenue reached 3.892 billion yuan, up 15.5% year-on-year, with a gross margin of 44.9%, an increase of 0.9 percentage points. New orders in this segment grew by over 10% [2]. - **CMC Services**: Revenue was 1.390 billion yuan, an 18.2% increase year-on-year, with a gross margin of 30.2%, up 2.4 percentage points. New orders in this segment grew by approximately 20% [2]. - **Clinical Research Services**: Revenue was 939 million yuan, an 11.4% increase year-on-year, with a gross margin of 12.3%, slightly down by 0.3 percentage points [3]. - **Large Molecule and Cell & Gene Therapy Services**: Revenue was 211 million yuan, remaining stable year-on-year, but with a gross margin of -54.7%, indicating losses due to high operational costs [3]. Customer and Regional Analysis - The company added over 480 new clients in H1 2025, contributing 128 million yuan, while existing clients generated 6.313 billion yuan, accounting for 98.01% of total revenue [4]. - Revenue from the top 20 global pharmaceutical companies was 1.168 billion yuan, a significant increase of 47.98% year-on-year [5]. - Revenue distribution by region showed North America contributing 4.073 billion yuan (up 11.02%), Europe 1.234 billion yuan (up 30.52%), and China 973 million yuan (up 15.48%) [5]. Financial Projections - Revenue projections for 2025-2027 are 13.865 billion yuan, 15.591 billion yuan, and 17.560 billion yuan, respectively, with net profits of 1.718 billion yuan, 1.985 billion yuan, and 2.302 billion yuan [7]. - The expected EPS for the same period is 0.97 yuan, 1.12 yuan, and 1.29 yuan, with corresponding P/E ratios of 31.16, 26.96, and 23.25 [7].

Performance Overview - Revenue for 2Q2025 reached RMB 3,342 million, a 7.9% increase QoQ and a 13.9% increase YoY [14] - Net profit for 2Q2025 was RMB 396 million, reflecting a 29.5% increase QoQ but a 55.2% decrease YoY due to prior investment income [14] - Non-IFRS net profit for 2Q2025 was RMB 406 million, showing a 16.3% increase QoQ and a 15.6% increase YoY [14] Financial Highlights - Total revenue for 1H2025 was RMB 6,441 million, a 14.9% increase YoY [15] - Net profit for 1H2025 was RMB 701 million, down 37.0% YoY [15] - Non-IFRS net profit for 1H2025 was RMB 756 million, a 9.5% increase YoY [15] Customer and Market Insights - New purchase orders (POs) increased by over 10% YoY [15] - Revenue from the top 20 global pharmaceutical companies increased by 48.0% YoY [15] - Active customer base includes over 2,600 customers, with 480+ new customers added [16] Revenue Composition - Revenue from China entities accounted for 88%, while overseas subsidiaries contributed 12% [19] - Laboratory services made up 60% of total revenue, followed by small molecule CDMO services at 22% and clinical development services at 15% [19] Global Presence and Projects - The company is involved in 795 drug discovery projects and 1,027 clinical CRO projects, including 89 in Phase III [17] - The company operates 21 R&D and manufacturing facilities across China, the UK, and the US [16] Future Outlook - The company expects to maintain a full-year 2025 revenue growth guidance of 10-15% [15] - Anticipated recovery in demand from Chinese customers, alongside sustained global customer demand [54]

Financial Performance - Revenue for Q2 2025 reached RMB 3,342 million, a 7.9% increase from Q1 2025 and a 13.9% increase year-over-year from Q2 2024 [14] - Net profit attributable to shareholders for Q2 2025 was RMB 396 million, a 29.5% increase from Q1 2025 but a 55.2% decrease year-over-year from Q2 2024 [14] - Non-IFRS adjusted net profit for Q2 2025 was RMB 406 million, reflecting a 16.3% increase from Q1 2025 and a 15.6% increase year-over-year [14] Revenue Breakdown - For 1H 2025, total revenue was RMB 6,441 million, a 14.9% increase compared to 1H 2024 [15] - New orders increased by over 10% year-over-year, with revenue from top 20 pharmaceutical companies growing by 48% [15] - Revenue composition: 88% from domestic delivery and 12% from overseas delivery [18] Client and Market Insights - Active clients exceeded 2,600, including over 480 new clients, with significant contributions from the top 20 pharmaceutical companies [16] - Revenue growth from North American clients was 11%, European clients 30.5%, and Chinese clients 15.5% [19] - The company maintains a target of 10-15% revenue growth for the full year 2025 [55] ESG and Sustainability Initiatives - The company achieved an AA rating in the latest MSCI ESG assessment [24] - It has joined the United Nations Global Compact and aims for the highest ESG ratings in the Asia-Pacific region by 2025 [28][29] - Efforts include achieving 100% renewable electricity usage in some facilities and expanding information security management systems [26] Operational Highlights - The company participated in 795 drug discovery projects and has a robust pipeline for long-term growth [16] - Clinical research services included 1,027 projects, with 89 in Phase III trials [36] - The company is enhancing its AI capabilities through partnerships and new technology integrations [16]