上海医药集团股份有限公司 关于上海上实集团财务有限公司 2023 半年度风险持续评估报 告 根据《上海证券交易所上市公司自律监管指引第 5 号——交易与关联交易》的 要求，上海医药集团股份有限公司（以下简称"上海医药"或"我们"）通过查验 上海上实集团财务有限公司（以下简称"财务公司"）的《金融许可证》、《营业 执照》等证件资料，审阅其二〇二三年度中期财务报表，对经营资质、业务和风险 状况进行了解和评估。具体情况报告如下： 一、 企业基本情况及经营资质 上海上实集团财务有限公司由上海上实（集团）有限公司（股东一）、上海医 药集团股份有限公司（股东二）、上海上实资产经营有限公司（股东三）以及上海 实业东滩投资开发（集团）有限公司（股东四）合资成立。2014 年 9 月 1 日在中华 人民共和国上海市注册成立的有限责任公司。 财务公司于 2014 年 8 月 26 日取得中国银行业监督管理委员会上海监管局的沪 银监复、[2014]561 号开业批复，于 2014 年 9 月 1 日成立，注册资本人民币 10 亿 元整，己于 2014 年 5 月 19 日全部缴入。财务公司取得上海市黄浦区市场监督管理 局颁发的 0 ...

证券代码：601607 证券简称：上海医药 公告编号：临 2023-069 上海医药集团股份有限公司 关于召开 2023 年半年度业绩说明会的公告 本公司董事会及全体董事保证本公告内容不存在任何虚假记载、误导性陈述 或者重大遗漏，并对其内容的真实性、准确性和完整性承担法律责任。 重要内容提示： （网址：https://roadshow.sseinfo.com/） 会议召开方式：上证路演中心网络互动 投资者可于 2023 年 8 月 25 日(周五)至 8 月 29 日(周二)16:00 前登录上证路演中心网站首页点击"提问预征集"栏目进行提问。公 司将在说明会上对投资者普遍关注的问题进行回答。 上海医药集团股份有限公司（以下简称"公司"）将于 2023 年 8 月 29 日发布公司 2023 年半年度报告，为便于广大投资者更全面深入 地了解公司 2023 年上半年经营成果、财务状况，公司计划于 2023 年 8 月 30 日下午 13:00-14:00 举行 2023 年半年度业绩说明会，就投资 者关心的问题进行交流。 一、 说明会类型 本次投资者说明会以网络互动形式召开，公司将针对 2023 年上 半年的经 ...

证券代码：601607 证券简称：上海医药 编号：临2023-068 上海医药集团股份有限公司 关于盐酸美金刚片获得批准生产的公告 本公司董事会及全体董事保证本公告内容不存在任何虚假记载、误导性陈述 或者重大遗漏，并对其内容的真实性、准确性和完整性承担个别及连带责任。 近日，上海医药集团股份有限公司（以下简称"上海医药"或"公司"）下 属控股子公司上海上药中西制药有限公司（以下简称"上药中西"）的盐酸美金 刚片（以下简称"该药品"）收到国家药品监督管理局（以下简称"国家药监局"） 颁发的《药品注册证书》（证书编号：2023S01232、2023S01233），该药品获得 批准生产。 一、该药品基本情况 药物名称：盐酸美金刚片 剂型：片剂 规格：10mg、20mg 二、 该药品相关的信息 盐酸美金刚片主要用于治疗中重度至重度阿尔茨海默型痴呆。最早由 Merz 公司研发。2002 年，该产品在欧盟批准上市。2021 年 3 月，上药中西就该药品 向国家药监局提出注册上市申请，并获受理。 截至本公告日，中国境内该药品的主要生产厂家包括珠海联邦制药股份有 限公司中山分公司、湖南洞庭药业股份有限公司、广州白云山医药集团 ...

Financial Performance - Shanghai Pharmaceuticals reported a revenue of RMB 100 billion for the fiscal year 2022, representing a year-on-year growth of 12%[11]. - The company achieved a net profit of RMB 8 billion, which is an increase of 15% compared to the previous year[11]. - Shanghai Pharmaceuticals achieved a revenue of RMB 231.98 billion in 2022, an increase of approximately 7.4% compared to RMB 215.82 billion in 2021[25]. - The company's pre-tax profit for 2022 was RMB 8.81 billion, reflecting a growth of about 8.2% from RMB 8.14 billion in 2021[25]. - The net profit attributable to shareholders was RMB 5.62 billion in 2022, representing a growth of around 10.3% from RMB 5.09 billion in 2021[25]. - The company reported a significant increase in sales costs, management expenses, and financial costs, with changes exceeding 30% year-on-year[93]. - The company reported a sales revenue increase of 7.49% compared to the previous year, reaching approximately ¥231.98 billion[88]. Research and Development - The company is investing RMB 1.5 billion in R&D for innovative drug development, aiming to introduce at least two first-in-class drugs by 2025[11]. - The company has increased its R&D investment by over RMB 2 billion compared to five years ago, indicating a strong commitment to innovation[28]. - Research and development investment totaled RMB 2.8 billion, marking an 11.87% increase compared to the previous year[34]. - The company has expanded its innovative drug pipeline from 16 to 50 projects since 2017, with two new drug applications recently submitted[34]. - The company is actively expanding its research and development efforts across various therapeutic areas, including oncology, autoimmune diseases, and metabolic disorders[49]. - The company has established partnerships with several universities and research institutions to enhance its innovative drug development capabilities[61]. - The company aims to enhance the quality and quantity of R&D outcomes by reforming its innovation mechanism and focusing on patient needs[110]. Market Expansion and Strategy - Shanghai Pharmaceuticals plans to launch three new products in the next fiscal year, targeting a market share increase of 5% in the pharmaceutical sector[11]. - Market expansion efforts include entering two new international markets, with projected revenue contributions of RMB 2 billion in the first year[11]. - The company is exploring strategic acquisitions to enhance its product portfolio, with a budget of RMB 3 billion allocated for potential mergers and acquisitions[11]. - Shanghai Pharma's internationalization strategy made significant progress with the establishment of subsidiaries in Thailand and a joint venture in Singapore, expanding its global business footprint[42]. - The company plans to establish 30 high-quality overseas Chinese medicine centers and develop 50 international cooperation bases to enhance its global presence[73]. - The company aims to enhance its market position by leveraging synergies across its pharmaceutical and retail segments, capitalizing on the continuous growth opportunities in China's healthcare sector[71]. Financial Health and Investments - Total assets reached RMB 198.13 billion in 2022, up from RMB 163.44 billion in 2021, marking an increase of approximately 21.2%[26]. - Total liabilities rose to RMB 120.13 billion in 2022, an increase of approximately 15.1% from RMB 104.37 billion in 2021[26]. - The company has a robust financial structure with a well-controlled debt-to-asset ratio, enhancing its capital operation capabilities[86]. - The company reported a significant rise in asset impairment losses, increasing by 136.02% to ¥331.47 million, indicating higher provisions for production-related asset impairments[88]. - The cash flow from financing activities surged by 675.32% to ¥12.14 billion, attributed to cash received from a private placement of shares[88]. - The company has a stable profit distribution policy, ensuring that cash dividends over the last three years account for at least 30% of the average distributable profits[118]. Corporate Governance and Compliance - The company has established internal compliance and risk management policies to ensure adherence to applicable laws and regulations in both mainland China and Hong Kong[181]. - The company has not issued, repurchased, sold, or redeemed any bonds during the fiscal year ending December 31, 2022[183]. - The company confirmed that all related party transactions were conducted under normal commercial terms and did not exceed the approved limits[179]. - The company has implemented a performance evaluation mechanism based on core, operational, and constraint indicators to determine compensation for directors and senior management[192]. - The company has a non-competition agreement with its major shareholders, ensuring they do not engage in competing businesses or investments[196]. Employee and Talent Management - The company has established a differentiated compensation system for various roles, including management, marketing, R&D, and production, to enhance employee motivation and performance[192]. - In 2022, the company organized 26 training projects, 62 classes, and 24 forums, with a total of 12,802 participants in its empowerment training programs[195]. - The company has developed a comprehensive training system to enhance leadership and professional capabilities, including international management training[195]. - The company has a mechanism in place to ensure that employee income growth is linked to company performance, allowing employees to share in the company's success[192]. Shareholder Information - The top ten shareholders held a total of 1,329,695,237 shares, representing 40.52% of the total issued shares[130]. - Shanghai Pharmaceuticals Group holds 716,516,039 shares, accounting for 19.38% of the total issued shares[130]. - The company plans to distribute a cash dividend of RMB 6.10 per 10 shares, totaling RMB 2,255,503,164.92, which accounts for 40.15% of the net profit attributable to shareholders for the year[115]. - The company has granted a total of 25,600,000 stock options to 210 incentive targets as of December 19, 2019, which was later adjusted to 23,258,120 options for 190 targets due to personnel changes[134][136]. Risks and Challenges - The company faces risks related to geopolitical and international economic conditions, which may impact international trade and investment in the short term[114]. - The company will closely monitor industry changes and increase R&D investment to mitigate risks associated with project development and clinical trial outcomes[114]. - The domestic pharmaceutical industry is witnessing a shift towards innovation-driven development, with policies promoting the accessibility of innovative products[106].

Financial Performance - In Q1 2023, the company achieved revenue of 66.226 billion RMB, a year-on-year increase of 16.39%[9] - The pharmaceutical manufacturing segment generated sales revenue of 7.801 billion RMB, up 12.60% year-on-year, with 60 key products contributing 4.604 billion RMB, a 13.84% increase[9] - The pharmaceutical commercial segment reported sales revenue of 58.425 billion RMB, reflecting a year-on-year growth of 16.92%[9] - The net profit attributable to shareholders was 1.518 billion RMB, representing a year-on-year increase of 21.31%, with the industrial business contributing 0.708 billion RMB and the commercial business contributing 0.861 billion RMB[9] - The company's revenue for the first quarter of 2023 was approximately ¥66.23 billion, representing a year-on-year increase of 16.39%[19] - The net profit attributable to shareholders was approximately ¥1.52 billion, reflecting a year-on-year growth of 21.31%[19] - Total operating revenue for Q1 2023 reached ¥66.23 billion, a 16.5% increase from ¥56.90 billion in Q1 2022[32] - Net profit for Q1 2023 was ¥1.95 billion, representing a 27.5% increase compared to ¥1.53 billion in Q1 2022[34] Research and Development - R&D investment reached 0.547 billion RMB, a 15.80% increase year-on-year, with R&D expenses at 0.541 billion RMB, up 20.82%[9] - The company has 64 new drug candidates in clinical research, including 52 innovative drugs and 12 improved new drugs[11] - The first self-developed new drug, I001, has completed Phase III clinical trials for hypertension, showing positive results[11] - The company has submitted a pre-NDA application for the new drug I008-A, targeting chronic immune disorders, which is expected to fill a clinical gap[12] - Research and development expenses for Q1 2023 were ¥540.69 million, an increase of 20.8% from ¥447.50 million in Q1 2022[33] - Research and development expenses increased to CNY 124,552,189.62 in Q1 2023 from CNY 106,026,867.46 in Q1 2022, reflecting a growth of about 17.5%[42] Market Expansion - The company is expanding its traditional Chinese medicine segment, leveraging historical brands and products with significant cultural heritage[13] - The company aims to enhance its market position in the Chinese medicine sector, supported by national policies promoting the industry[13] - The company has expanded its international presence by entering the Philippine market, with the approval of four specifications of Rosuvastatin Calcium Tablets[16] - The company plans to continue focusing on the Southeast Asian market to enhance its global commercial footprint[16] Assets and Liabilities - The total assets at the end of the reporting period were approximately ¥206.04 billion, an increase of 3.99% compared to the end of the previous year[19] - As of March 31, 2023, the total assets of the company amounted to RMB 206,035,799,280.43, an increase from RMB 198,134,901,498.95 as of December 31, 2022, reflecting a growth of approximately 4.8%[28] - The company's current assets totaled RMB 157,170,379,297.84, up from RMB 149,512,870,619.79, indicating an increase of about 5.5%[28] - Total liabilities as of Q1 2023 amounted to ¥126.15 billion, an increase from ¥120.13 billion in the previous year[30] - The total liabilities increased to CNY 24.60 billion from CNY 22.29 billion at the end of 2022[41] Cash Flow - The cash flow from operating activities was negative at approximately -¥2.62 billion, indicating increased cash outflows for purchases and services[19] - In Q1 2023, the company reported cash inflows from operating activities of approximately CNY 64.27 billion, an increase of 15.5% compared to CNY 55.91 billion in Q1 2022[35] - The net cash outflow from operating activities was CNY -2.62 billion, slightly worse than the CNY -2.49 billion reported in the same period last year[36] - The company generated CNY 9.56 billion from investment activities, a significant increase from CNY 180.58 million in Q1 2022[36] - The net cash outflow from investment activities was CNY -2.11 billion, compared to CNY -631.10 million in the previous year[36] - Cash inflows from financing activities totaled CNY 26.49 billion, down from CNY 34.75 billion in Q1 2022[36] - The net cash inflow from financing activities was CNY 4.31 billion, a decrease from CNY 17.59 billion in the same quarter last year[36] Shareholder Information - The number of ordinary shareholders at the end of the reporting period was 78,061[24] - The company reported a total of 3,698,499,159 shares issued, comprising 2,779,426,455 A-shares and 919,072,704 H-shares[26] Financial Ratios - The weighted average return on equity decreased to 2.24%, down by 0.26 percentage points from the previous year[19] - Total equity for Q1 2023 was ¥79.88 billion, up from ¥78.00 billion in Q1 2022[30] - The company's long-term borrowings increased to ¥8.60 billion in Q1 2023 from ¥6.26 billion in Q1 2022[30] - The company's financial expenses decreased to CNY 57,188,926.70 in Q1 2023 from CNY 80,460,137.77 in Q1 2022, a reduction of approximately 29%[42]

Financial Performance - The company achieved operating revenue of RMB 66.226 billion in Q1 2023, representing a year-on-year growth of 16.39%[7] - The net profit attributable to shareholders was RMB 1.518 billion, reflecting a year-on-year growth of 21.31%[7] - The pharmaceutical commercial segment generated RMB 58.425 billion in sales, marking a year-on-year growth of 16.92%[7] - The sales of the innovative drug segment increased by approximately 28% year-on-year, with 7 new imported products introduced[13] - Net profit for Q1 2023 reached approximately ¥1.95 billion, up 27.5% from ¥1.53 billion in Q1 2022[27] - Total comprehensive income for Q1 2023 was approximately ¥1.92 billion, compared to ¥1.49 billion in Q1 2022, reflecting a growth of 28.7%[29] - Basic earnings per share for Q1 2023 were ¥0.41, a decrease from ¥0.44 in Q1 2022[29] - The company reported a basic earnings per share of ¥0.41, down by 6.75% year-on-year[14] Research and Development - R&D investment totaled RMB 547 million, an increase of 15.80% year-on-year, with R&D expenses at RMB 541 million, up 20.82%[7] - The company has 64 new drug candidates in clinical research, including 52 innovative drugs and 12 improved new drugs[9] - The first self-developed 1.1 class new drug, I001, has completed Phase III clinical trials for hypertension, achieving primary endpoint success[10] - The company submitted a pre-NDA application for I008-A, targeting chronic immune disorders related to HIV, aiming to fill clinical gaps[10] - R&D expenses increased to ¥540.69 million in Q1 2023, compared to ¥447.50 million in Q1 2022, indicating a focus on innovation[26] - Research and development expenses increased to ¥124,552,189.62 in Q1 2023 from ¥106,026,867.46 in Q1 2022, reflecting a growth of approximately 17.5%[36] Financial Position - The total assets at the end of the reporting period were ¥206,035,799,280.43, a 3.99% increase from the previous year[15] - The company's total assets reached ¥206.04 billion as of March 31, 2023, up from ¥198.13 billion at the end of 2022[25] - The equity attributable to shareholders increased to ¥68.57 billion as of March 31, 2023, from ¥67.06 billion at the end of 2022, reflecting growth in shareholder value[25] - Total liabilities increased to ¥126.15 billion as of March 31, 2023, compared to ¥120.13 billion at the end of 2022, indicating higher financial obligations[25] - The company's current assets totaled RMB 157,170,379,297.84 as of March 31, 2023, compared to RMB 149,512,870,619.79 as of December 31, 2022, reflecting an increase[22] Cash Flow - The net cash flow from operating activities was negative at -¥2,623,322,412.29, indicating a significant cash outflow[14] - Cash inflow from operating activities in Q1 2023 was approximately ¥64.27 billion, an increase from ¥55.91 billion in Q1 2022[30] - Cash outflow from operating activities totaled approximately ¥66.90 billion in Q1 2023, compared to ¥58.40 billion in Q1 2022[31] - The company reported cash inflow from investment activities of approximately ¥9.56 billion in Q1 2023, significantly higher than ¥180.58 million in Q1 2022[31] - Cash outflow from investment activities in Q1 2023 was approximately ¥11.67 billion, compared to ¥811.68 million in Q1 2022[31] - The total cash and cash equivalents at the end of Q1 2023 amounted to ¥24,104,731,465.82, down from ¥34,611,200,668.81 at the end of 2022, representing a decrease of 30.5%[32] Shareholder Information - The total number of common shareholders at the end of the reporting period was 78,061[20] - The top three shareholders held the following shares: Shanghai Pharmaceuticals Group (716,516,039 shares, 19.373%), HKSCC Nominees Limited (689,221,624 shares, 18.635%), and Yunnan Baiyao (665,626,796 shares, 17.997%)[19] - The total number of issued A-shares was 2,779,426,455 and H-shares was 919,072,704, totaling 3,698,499,159 shares[20] Market Expansion - The company is focusing on the traditional Chinese medicine sector, with plans to enhance the value of its eight core TCM enterprises[11] - The company plans to continue deepening its focus on the Southeast Asian market and expanding its global commercial footprint[13] - The company expanded its international presence by launching four specifications of Rosuvastatin Calcium Tablets in the Philippines[13] Investment Performance - The profit contribution from major equity investments was RMB 177 million, down 15.12% year-on-year[7] - The company reported a net investment income of ¥155.16 million in Q1 2023, down from ¥179.73 million in Q1 2022, indicating fluctuations in investment performance[26] - Investment income for Q1 2023 was reported at ¥225,801,358.48, compared to ¥192,498,159.54 in Q1 2022, showing an increase of approximately 17.3%[36]

证券代码：601607 证券简称：上海医药 公告编号：临 2023-040 上海医药集团股份有限公司 关于召开 2023 年第一季度业绩说明会的公告 本公司董事会及全体董事保证本公告内容不存在任何虚假记载、误导性陈述 或者重大遗漏，并对其内容的真实性、准确性和完整性承担个别及连带责任。 重要内容提示： （网址：http://roadshow.sseinfo.com/） 会议召开方式：上证路演中心音频直播结合网络互动 投资者可于 2023 年 04 月 23 日(星期天) 至 04 月 26 日(星期三)16:00 前登 录上证路演中心网站首页点击"提问预征集"栏目或通过公司邮箱 boardoffice@sphchina.com 进行提问。公司将在说明会上对投资者普遍关注的 问题进行回答。 上海医药集团股份有限公司（以下简称"公司"）将于 2023 年 4 月 26 日晚 发布《公司 2023 年第一季度报告》。为便于广大投资者更全面深入地了解公司 2023 年第一季度的经营成果和财务状况，公司计划于 2023 年 04 月 27 日下午 13:00-14:00 举行 2023 年第一季度业绩说明会，就投资者关 ...

Financial Performance - Shanghai Pharmaceuticals achieved over 200 billion RMB in revenue in 2022, ranking 430th in the Fortune Global 500, an increase of 7 places from the previous year[3]. - Shanghai Pharmaceuticals reported a total revenue of RMB 30.5 billion for the year 2022, representing a year-on-year increase of 12%[17]. - The company's net profit attributable to shareholders was RMB 2.1 billion, reflecting a growth of 15% compared to the previous year[17]. - The company's operating revenue for 2022 was CNY 231.98 billion, an increase of 7.49% compared to CNY 215.82 billion in 2021[23]. - Net profit attributable to shareholders for 2022 was CNY 5.62 billion, reflecting a growth of 10.28% from CNY 5.09 billion in 2021[23]. - The gross margin for the year 2022 was reported at 35%, a slight improvement from 34% in the previous year[17]. - The company aims for a revenue growth target of 10-12% for the fiscal year 2023[17]. - The company reported a significant increase in revenue, achieving a total of $1.5 billion for the fiscal year, representing a 20% year-over-year growth[146]. - The company provided guidance for the next fiscal year, projecting revenue growth of 25% and aiming for $1.875 billion[146]. - The company reported a significant increase in revenue, achieving a total of 10 billion RMB for the fiscal year, representing a 15% year-over-year growth[151]. Research and Development - R&D investment grew from 670 million RMB in 2016 to 2.8 billion RMB in 2022, nearly a fivefold increase, with the number of innovative drug pipelines expanding from 16 to 50[3][4]. - The company has built a comprehensive R&D system covering small molecules, macromolecules, and high-end formulations, enhancing its innovation capabilities[4]. - Shanghai Pharmaceuticals is investing RMB 500 million in R&D for new drug development, focusing on oncology and chronic diseases[17]. - The company has launched two Class 1 new drug applications recently, marking its entry into a new drug development harvest period[3]. - The company has 62 new drug projects in the pipeline, with 50 being innovative drugs, and 2 projects submitted for pre-NDA or listing applications[40]. - The company is actively collaborating with top research institutions and startups to drive original innovation in biomedicine[4]. - The company is focused on enhancing patient compliance and treatment efficacy through innovative drug delivery methods, as demonstrated by the B007 project[44]. - The company is actively pursuing new indications and expanding its clinical trial portfolio, with multiple projects in various stages of development[42]. - The company is committed to increasing R&D investment and optimizing resource allocation to drive innovation[68]. - The company is investing in R&D, with a budget increase of 25% for new technology development[148]. Market Expansion and Strategy - The company plans to expand its market presence in Southeast Asia, targeting a revenue contribution of 10% from this region by 2025[17]. - The company is exploring potential acquisitions in the biotechnology sector to enhance its product pipeline and market reach[17]. - The company is expanding its market presence in Southeast Asia, targeting a 25% market share within the next three years[151]. - The company plans to implement a new digital marketing strategy, aiming to increase online sales by 40%[146]. - The company is considering strategic acquisitions to enhance its product portfolio, targeting a deal worth approximately $100 million[147]. - The company is actively exploring new business areas in medical devices, aesthetic medicine, and health foods to diversify its offerings[61]. - The company is committed to digital transformation, leveraging big data to improve management efficiency and organizational effectiveness[131]. - The company is focusing on the development of traditional Chinese medicine and aims to revitalize well-known brands in this sector[129]. Financial Structure and Investments - The company completed a major private placement project, raising nearly 14 billion RMB, and introduced Yunnan Baiyao as a strategic investor[6]. - The company has raised approximately RMB 14 billion through a non-public issuance of 852,626,796 A shares, with funds allocated for operational capital and debt repayment[133]. - The company maintains a strong financial structure with a good control of the debt-to-asset ratio, leveraging its A+H share listing for capital operations[79]. - The total amount of short-term borrowings increased significantly, with bank pledge borrowings reaching CNY 11.55 billion[94]. - The company reported a significant increase in capitalized R&D expenses, amounting to CNY 342,605,253.63, a 32.16% increase from CNY 259,227,946.08[92]. Corporate Governance and Management - The company’s board consists of 10 members, including 4 independent non-executive directors with expertise in accounting, law, and pharmaceuticals, ensuring compliance with governance standards[139]. - The company has implemented strict information disclosure practices to maintain transparency and protect stakeholder interests[139]. - The total remuneration for all directors, supervisors, and senior management in 2022 amounted to RMB 47.301 million[155]. - The company has established a comprehensive evaluation mechanism for assessing the performance of directors and senior management based on key operational indicators[155]. - The company has seen changes in senior management, including the retirement of a vice president due to age and the appointment of new executives for business needs[156]. Environmental Responsibility - The company invested 11,850,000 RMB in environmental protection during the reporting period[180]. - The company has established an environmental protection mechanism and is classified as a key pollutant discharge unit[180]. - The company is focusing on reducing volatile organic compounds (VOCs) emissions, with a reported level of 12.14 mg/m³, which is within the acceptable range[185]. - The company plans to enhance its wastewater treatment capabilities to meet stricter environmental regulations in the future[186]. - The company conducted a total of 2 comprehensive emergency drills and 9 on-site response drills throughout 2022 to improve employees' emergency response abilities[199].

证券代码：601607 证券简称：上海医药 公告编号：2023-018 上海医药集团股份有限公司 关于召开 2022 年年度业绩说明会的公告 本公司董事会及全体董事保证本公告内容不存在任何虚假记载、误导性陈述 或者重大遗漏，并对其内容的真实性、准确性和完整性承担个别及连带责任。 重要内容提示： 投资者可于 2023 年 3 月 24 日(星期五) 至 3 月 30 日(星期四)16:00 前 登录上证路演中心网站首页点击"提问预征集"栏目或通过公司邮箱 board office@sphchina.com 进行提问。公司将在说明会上对投资者普遍关注的问 题进行回答。 上海医药集团股份有限公司（以下简称"公司"）将于 2023 年 3 月 30 日收 盘后发布公司 2022 年年度报告，为便于广大投资者更全面深入地了解公司 2022 年年度经营成果、财务状况，公司计划于 2023 年 3 月 31 日下午 15:00-16:30 举 行 2022 年度业绩说明会，就投资者关心的问题进行交流。 一、说明会类型 本次投资者说明会以音频直播结合网络互动召开，公司将针对 2022 年度经 营成果及财务指标的具体情况与投资 ...

Financial Performance - For the first nine months of 2022, Shanghai Pharmaceuticals achieved operating revenue of RMB 174.612 billion, a year-on-year increase of 8.47%[7] - The net profit attributable to shareholders for the first nine months was RMB 4.814 billion, an increase of 7.35% year-on-year[7] - The company’s net profit attributable to shareholders for Q3 2022 was RMB 1.118 billion, a year-on-year increase of 22.02%[7] - Total operating revenue for the first three quarters of 2022 reached ¥174.61 billion, an increase of 8.8% compared to ¥160.97 billion in the same period of 2021[26] - Net profit for the first three quarters of 2022 was ¥5.98 billion, compared to ¥5.36 billion in the same period of 2021, representing a growth of 11.5%[27] Revenue Breakdown - The pharmaceutical manufacturing segment generated sales revenue of RMB 19.793 billion, up 5.35% year-on-year, with a gross margin of 58.05%[8] - The pharmaceutical distribution business achieved sales revenue of CNY 155.198 billion from January to September 2022, a year-on-year increase of 9.33%, with a gross margin of 6.28%[10] - The pharmaceutical retail business reported sales revenue of CNY 5.680 billion during the same period, reflecting a year-on-year growth of 0.76%, with a gross margin of 11.74%[10] Research and Development - Research and development expenses for the first nine months totaled RMB 1.692 billion, a decrease of 1.34% year-on-year, while capitalized R&D expenses were RMB 1.389 billion, up 1.63%[7] - The company has 53 new drug candidates in clinical research, including 43 innovative drugs and 10 improved new drugs[8] - Shanghai Pharmaceuticals has received approval for clinical trials for its anti-tumor drug B013 and autoimmune drug I001-B, with trials set to begin soon[8] - Research and development expenses for the first three quarters of 2022 were ¥1.39 billion, slightly up from ¥1.37 billion in the same period of 2021, indicating a year-on-year increase of 1.4%[26] Assets and Liabilities - The total assets as of the end of the reporting period reached CNY 194.618 billion, a year-on-year increase of 19.08%[12] - The equity attributable to shareholders at the end of the reporting period was CNY 66.175 billion, reflecting a year-on-year increase of 34.07%[12] - The total liabilities of the company reached RMB 107.40 billion, compared to RMB 91.82 billion in the previous year, indicating an increase of around 16.9%[23] - The company's total liabilities as of the end of the third quarter of 2022 amounted to ¥118.00 billion, an increase from ¥104.37 billion at the end of the previous year, marking a rise of 13.1%[26] Cash Flow - The company’s cash flow from operating activities for the year-to-date period decreased by 105.43% due to the impact of the pandemic on cash collection[15] - The cash inflow from operating activities for the first three quarters of 2022 was approximately ¥185.77 billion, an increase from ¥177.08 billion in the same period of 2021, representing a growth of about 4.8%[30] - The net cash outflow from operating activities in Q3 2022 was approximately -¥158.75 million, a significant decrease compared to a net inflow of ¥2.92 billion in Q3 2021[31] - The net cash flow from operating activities for the first three quarters of 2022 was -224,878,559.54 RMB, compared to -97,053,307.81 RMB in the same period of 2021, indicating a decline in operational cash flow[40] Strategic Initiatives - The company is actively expanding into the vaccine sector, with its subsidiary having full GMP production capabilities for viral vector drugs[9] - The company is actively developing an "Internet+" pharmaceutical commercial technology platform, enhancing digital business and internet platform upgrades[10] - The company signed strategic cooperation agreements with Abbott, Green Leaf Pharmaceutical, and Luoxin Pharmaceutical in September 2022, leveraging its comprehensive distribution and retail network[10] Shareholder Information - The company reported a total of 3,696,414,318 shares issued, with 2,777,341,614 A-shares and 919,072,704 H-shares as of the report date[19] - The number of shareholders stood at 113,835, with 112,053 holding A-shares and 1,782 holding H-shares[19]