Group 1 - The core point of the article highlights that Junshi Biosciences experienced a stock price increase of 0.50%, closing at 48.50 yuan, with a significant block trade of 1 million shares totaling 48.16 million yuan [1] - The first transaction occurred at a price of 48.16 yuan for 1 million shares, resulting in a transaction amount of 48.16 million yuan, with a premium rate of -0.70% [1] - The buyer was from Founder Securities Co., Ltd., while the seller was from CITIC Securities Co., Ltd. [1] Group 2 - Over the past three months, Junshi Biosciences has recorded a total of 4 block trades, with a cumulative transaction amount of 191 million yuan [1] - In the last five trading days, the stock has risen by 4.59%, with a net inflow of main funds amounting to 26.42 million yuan [1]

Summary of Key Points Core Viewpoint - On September 10, Junshi Biosciences executed a block trade of 1 million shares, amounting to 48.16 million yuan, which represented 4.52% of the total trading volume for that day, with a transaction price of 48.16 yuan, reflecting a discount of 0.7% compared to the market closing price of 48.5 yuan [1][2]. Group 1 - The block trade involved 1 million shares of Junshi Biosciences [1]. - The total transaction amount was 48.16 million yuan [1]. - The transaction price was set at 48.16 yuan per share, which is lower than the market closing price [1][2]. Group 2 - The block trade accounted for 4.52% of the total trading volume on that day [1]. - The discount on the transaction price was 0.7% compared to the market closing price [1].

两融数据显示，该股最新融资余额为12.96亿元，近5日增加577.87万元，增幅为0.45%。（数据宝） 9月9日君实生物-U大宗交易一览 | 成交量 | 成交金 | 成交价 | 相对当日 | | | | --- | --- | --- | --- | --- | --- | | （万 | 额 | | 收盘折溢 | 买方营业部 | 卖方营业部 | | | （万 | 格 | 价 | | | | 股） | 元） | （元） | （%） | | | | 100.00 | 4792.00 | 47.92 | -0.70 | 方正证券股份有限公 | 中信证券股份有限公司上海浦东新区东方路 | | | | | | 司总部 | 证券营业部 | （原标题：君实生物-U大宗交易成交100.00万股 成交额4792.00万元） 君实生物-U9月9日大宗交易平台出现一笔成交，成交量100.00万股，成交金额4792.00万元，大宗交易 成交价为47.92元，相对今日收盘价折价0.70%。该笔交易的买方营业部为方正证券股份有限公司总部， 卖方营业部为中信证券股份有限公司上海浦东新区东方路证券营业部。 进一步统计，近3个月内该股累计发 ...

Group 1 - The stock of Junshi Biosciences rose by 1.54%, closing at 48.26 yuan, with a significant block trade of 1 million shares totaling 47.92 million yuan [1] - The first transaction occurred at a price of 47.92 yuan for 1 million shares, with a premium rate of -0.70%, involving the buyer from Founder Securities and the seller from CITIC Securities [1] - Over the past three months, the stock has seen a total of three block trades with a cumulative transaction amount of 143 million yuan, and in the last five trading days, it has increased by 4.30% with a net inflow of 62.25 million yuan from main funds [1]

从基金十大重仓股角度 9月9日，君实生物涨5.11%，截至发稿，报49.96元/股，成交3.14亿元，换手率0.84%，总市值512.93亿 元。 资料显示，上海君实生物医药科技股份有限公司位于上海市浦东新区平家桥路100弄6号7幢16层,香港铜 锣湾希慎道33号利园1期19楼1918室，成立日期2012年12月27日，上市日期2020年7月15日，公司主营业 务涉及单克隆抗体药物和其他治疗型蛋白药物的研发与产业化,单克隆抗体药物研发的技术服务与技术 转让等。主营业务收入构成为：药品销售90.67%，技术许可及特许权使用收入8.74%，技术服务及其他 0.59%。 数据显示，鹏华基金旗下1只基金重仓君实生物。鹏华上证科创板生物医药ETF（588250）二季度持有 股数12.16万股，占基金净值比例为4.1%，位居第七大重仓股。根据测算，今日浮盈赚取约29.56万元。 鹏华上证科创板生物医药ETF（588250）成立日期2025年3月12日，最新规模1.01亿。成立以来收益 35.22%。 风险提示：市场有风险，投资需谨慎。本文为AI大模型自动发布，任何在本文出现的信息（包括但不 限于个股、评论、预测、图表、指 ...

Core Viewpoint - Junshi Biosciences (01877) experienced a significant stock increase of over 9%, with a current price of HKD 38.36 and a trading volume of HKD 173 million, following the positive results of its clinical trial for JS005, a monoclonal antibody targeting IL-17A in treating moderate to severe plaque psoriasis [1]. Group 1: Clinical Trial Results - The company announced that its product, JS005, achieved positive results in a pivotal Phase III clinical trial (Study No: JS005-005-III-PsO) for treating moderate to severe plaque psoriasis, meeting both primary and key secondary endpoints with statistical significance and clinical relevance [1]. - The trial demonstrated that JS005 significantly improved the psoriasis lesion area and severity compared to the placebo, with a notably higher proportion of participants achieving a sPGA score of 0 or 1 [1]. - The safety profile of JS005 was found to be good among participants with moderate to severe plaque psoriasis, and the results are planned to be presented at an upcoming international academic conference [1]. Group 2: Regulatory Plans - The company plans to submit a marketing authorization application for JS005 to regulatory authorities in the near future [1].

君实生物(01877)拉升逾9%，截至发稿，涨8.36%，报38.36港元，成交额1.73亿港元。 据介绍，JS005是公司自主研发的特异性抗IL-17A单克隆抗体。截至本公告披露日，JS005此项多中心、 随机、双盲、平行、安慰剂对照的关键注册性Ⅲ期临床研究(研究编号：JS005-005-Ⅲ-PsO)已顺利完 成，并达到共同主要研究终点和关键次要终点。 研究结果显示，与安慰剂相比，JS005可显著改善参与者的银屑病皮损面积和严重程度，达到sPGA评分 为0或1的参与者比例显著优于安慰剂，并在中重度斑块状银屑病参与者中安全性良好，相关研究结果计 划在未来国际学术会议上予以公布。 消息面上，君实生物发布公告，近日，公司产品重组人源化抗IL-17A单克隆抗体(代号：JS005)在治疗 中重度斑块状银屑病的一项多中心、随机、双盲、平行、安慰剂对照的关键注册性Ⅲ期临床研究(研究 编号：JS005-005-III-PsO)中取得阳性结果，共同主要研究终点和关键次要终点均具有统计学显著性和临 床意义的改善。公司计划将于近期向监管部门递交该产品的上市许可申请。 ...

Group 1 - The core viewpoint of the news highlights the trading performance and financing activities of Junshi Biosciences, indicating a high level of financing and short-selling activity, which may suggest investor sentiment and market dynamics [1] - On September 8, Junshi Biosciences experienced a decline of 0.98% in stock price, with a trading volume of 867 million yuan. The net financing purchase on that day was 15.66 million yuan, with a total financing and securities lending balance of 1.307 billion yuan [1] - The financing balance of Junshi Biosciences reached 1.296 billion yuan, accounting for 3.56% of its market capitalization, which is above the 90th percentile level over the past year, indicating a high financing level [1] Group 2 - Junshi Biosciences, established on December 27, 2012, focuses on the research and commercialization of monoclonal antibody drugs and other therapeutic protein drugs, with 90.67% of its revenue coming from drug sales [2] - For the first half of 2025, Junshi Biosciences reported a revenue of 1.168 billion yuan, representing a year-on-year growth of 48.64%, while the net profit attributable to shareholders was -413 million yuan, showing a year-on-year increase of 36.01% [2] - As of June 30, 2025, the number of shareholders of Junshi Biosciences increased by 5.88% to 31,200, while the average circulating shares per person decreased by 5.56% to 24,543 shares [2] Group 3 - As of June 30, 2025, among the top ten circulating shareholders of Junshi Biosciences, the Huaxia SSE STAR 50 ETF held 29.7167 million shares, a decrease of 536,700 shares from the previous period, while the E Fund SSE STAR 50 ETF increased its holdings by 630,000 shares to 22.2132 million shares [3] - Hong Kong Central Clearing Limited ranked as the tenth largest circulating shareholder with 13.1291 million shares, a decrease of 186,650 shares compared to the previous period [3]

Group 1 - The core point of the article is the recent large transaction involving Junshi Biosciences (君实生物-U), which occurred on September 8, with a transaction volume of 1 million shares and a transaction amount of 47.2 million yuan [2] - The transaction price was 47.20 yuan, representing a discount of 0.69% compared to the closing price of the same day [2] - The buyer was from Founder Securities Co., Ltd., while the seller was from CITIC Securities Co., Ltd. [2] Group 2 - In the last three months, Junshi Biosciences has recorded a total of 2 large transactions, with a cumulative transaction amount of 94.86 million yuan [2] - On the same day, the closing price of Junshi Biosciences was 47.53 yuan, showing a decrease of 0.98%, with a daily turnover rate of 2.36% and a total transaction amount of 867 million yuan [2] - The net inflow of main funds for the day was 9.28 million yuan, and over the past five days, the stock has increased by 0.89% with a total net inflow of 8.70 million yuan [2] Group 3 - The latest margin financing balance for Junshi Biosciences is 1.28 billion yuan, which has decreased by 2.47 million yuan over the past five days, reflecting a decline of 0.19% [2]

Group 1 - On September 8, Junshi Biosciences executed a block trade of 1 million shares, with a transaction value of 47.2 million yuan, accounting for 5.16% of the total trading volume on that day [1][2] - The transaction price was 47.2 yuan per share, which represents a discount of 0.69% compared to the market closing price of 47.53 yuan [1]