Core Viewpoint - Collegium Pharmaceutical, Inc. has authorized a new share repurchase program to buy back up to $150 million in common stock, replacing a previous program that had $65 million remaining [1][2]. Financial Position and Strategy - The company emphasizes its strong financial position, which allows for flexibility in capital allocation and supports shareholder value return [2]. - Since 2021, Collegium has returned $222 million to shareholders through share repurchase programs, including $25 million from an accelerated program initiated in May 2025 [2]. Share Repurchase Program Details - The new share repurchase program is set to run through December 31, 2026, and replaces a previous program that expired on June 30, 2025 [1]. - As of March 31, 2025, Collegium had approximately 32.1 million shares outstanding [3]. Company Overview - Collegium is focused on improving the lives of individuals with serious medical conditions and has a portfolio that includes pain management medications and the recently acquired Jornay PM® for ADHD [4]. - The company's strategy involves growing its commercial portfolio with Jornay PM as a key growth driver and disciplined capital deployment [4].

Core Viewpoint - The introduction of a "zero tariff" policy for imported medical devices and drugs in the Boao Lecheng International Medical Tourism Pilot Zone is facilitating the rapid entry of advanced medical technologies and products, benefiting both domestic and international patients [2][3]. Group 1: Policy Implementation - The "zero tariff" policy for imported medical devices and drugs was officially implemented on December 25, 2024, following the issuance of management measures by the Hainan provincial government [3]. - The Lecheng Pilot Zone has successfully integrated multiple departments to streamline the application process for "zero tariff" imports, reducing the administrative burden on medical institutions [4][6]. Group 2: Clinical Applications - The first clinical use of the Nexa smart cochlear implant system occurred at the Tree Lan (Boao) Hospital, with 50 units purchased, valued at approximately 15 million yuan, resulting in over 1 million yuan in tax exemptions [2][4]. - As of July 5, 2024, approximately 50 surgeries have been completed using the Nexa system, showcasing the immediate impact of the new policy on patient care [2]. Group 3: Regulatory Innovations - A comprehensive tracking management platform has been established to facilitate the application for "zero tariff" imports, allowing medical institutions to submit requests without leaving the hospital [3][4]. - The platform has enabled real-time data sharing between customs and medical institutions, enhancing efficiency and reducing redundancy in the application process [4][6]. Group 4: Future Developments - Continuous optimization of the platform and mechanisms is planned to expand the range of eligible medical devices and drugs, aiming to maximize the benefits of the policy for a larger population [7].

Group 1 - Collegium Pharmaceuticals (NASDAQ: COLL) stock is trading at over $30 per share, with a market capitalization just shy of $1 billion [1] - The company provides insights for both novice and experienced biotech investors, including catalysts to watch for and buy/sell ratings [1] - The investing group Haggerston BioHealth offers detailed reports on over 1,000 companies in the biotech, healthcare, and pharma sectors [1] Group 2 - The Q1 2025 quarterly report/10Q submission is referenced, indicating ongoing financial disclosures [1]

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Financial Performance and Guidance - Collegium reported 2024 sales of $631 million and expects 2025 sales to reach $743 million, representing an +18% increase[16] - The company anticipates 2025 net product revenues in the range of $735 million to $750 million, reflecting an +18% year-over-year growth[22] - Adjusted EBITDA for 2025 is projected to be between $435 million and $450 million, a +10% increase[22] - Adjusted operating expenses for 2025 are expected to be in the range of $220 million to $230 million, a +49% increase[22] Product Portfolio and Market Position - Jornay PM net revenue is expected to exceed $135 million in 2025, representing a +>34% increase from $100.7 million in 2024[40] - The pain portfolio experienced a +5% revenue growth in 2024, while total revenue grew +11%[20] - Q1 2025 pain portfolio product revenues reached $177.8 million, a +23% increase compared to $144.9 million in Q1 2024[32] - Jornay PM prescriptions grew +24% year-over-year in Q1 2025[32] Capital Allocation and Shareholder Value - Collegium initiated a $25 million Accelerated Share Repurchase (ASR) program in May 2025[33] - The company repurchased $222 million worth of shares between 2021 and 2025[47] Debt and Cash Flow - The company had approximately $200 million in cash and marketable securities at the end of Q1 2025[27] - Net debt to adjusted EBITDA stood at approximately 1.5x at the end of Q1 2025[33]

Summary of Collegium Pharmaceutical (COLL) Conference Call Company Overview - Collegium Pharmaceuticals is focused on building a diversified biopharmaceutical company, primarily addressing chronic pain and ADHD [2][3] - The company generated $631 million in net sales in 2024, with an expected growth of 18% to $743 million in 2025 [3][9] Product Portfolio - The company has five marketed products, including: - **Jornay PM**: $100 million in net sales in 2024, expected to exceed $135 million in 2025. It is the only ADHD medicine with once-daily evening dosing [5][6] - **BELBUCA**: $211 million in net sales in 2024, a long-acting opioid using buprenorphine buccal film technology [7] - **Xtampza ER**: $191 million in net sales in 2024, an extended-release oxycodone with abuse deterrent technology [8] - **Nucynta Franchise**: $177 million in net sales in 2024, treating severe and persistent pain as well as neuropathic pain [8] Financial Performance - Expected net revenues for 2025 are between $735 million and $750 million, indicating an 18% year-over-year growth [9] - Adjusted EBITDA is projected to be between $435 million and $450 million, representing a 10% year-over-year growth [10] - Adjusted operating expenses are expected to grow by 49% year-over-year due to the acquisition of Ionshore Therapeutics [10] Revenue Durability - The company has a strong expectation of revenue durability, with projected exclusivity for Xtampza ER through September 2033 and BELBUCA until January 2027 [14][15] - No generic competitors have satisfied all criteria to launch future generics, which supports the durability of the pain portfolio [17] Recent Business Highlights - In Q1 2025, the company achieved $177 million in net sales, a 23% increase from 2024 [18] - Cash from operations was over $55 million, with a leverage ratio of 1.5 net debt over EBITDA, expected to decrease to less than 1 by the end of 2025 [19] - A share repurchase program of $25 million was announced in May 2025 [19] Growth Strategies - The company is investing in Jornay PM to maximize growth and has expanded its sales team from 125 to 180 representatives [21][22] - Marketing programs are being implemented to raise awareness among caregivers and patients, aligning with the back-to-school season [23] Competitive Positioning - Collegium is positioned uniquely among biopharmaceutical peers with a robust revenue profile and double-digit growth [25] - The company has a strong cash generation profile and a history of returning value to shareholders, having repurchased $222 million in shares since 2021 [26][27] - The majority of its medicines are sourced and sold in the US, making them largely immune to tariffs and pricing pressures [28] Conclusion - Collegium Pharmaceuticals is well-positioned for continued growth, with a strong focus on revenue generation, profitability, and disciplined capital deployment strategies [28]

Core Viewpoint - Collegium Pharmaceutical, Inc. has initiated an Accelerated Share Repurchase (ASR) agreement to repurchase $25 million of its common stock as part of a broader $150 million share repurchase program, reflecting a strategic approach to capital allocation while driving revenue growth and returning capital to shareholders [1][2]. Group 1: Financial Performance - In the first quarter of 2025, Collegium reported a 23% year-over-year revenue growth, attributed to strong sales from its pain management portfolio and significant contributions from its ADHD medication, Jornay PM® [2]. - The ASR agreement will initially deliver 692,281 shares to Collegium, based on a closing stock price of $28.89 on May 9, 2025, which represents approximately 80% of the total shares expected to be repurchased [2]. Group 2: Strategic Initiatives - The Board of Directors authorized the $25 million ASR as part of a disciplined capital allocation strategy aimed at sustaining revenue growth while also returning capital to shareholders [2]. - Collegium's strategy includes expanding its commercial portfolio with Jornay PM as a key growth driver and investing in business development while managing debt and share repurchases [2][3]. Group 3: Company Overview - Collegium Pharmaceutical is a diversified biopharmaceutical company focused on improving the lives of individuals with serious medical conditions, with a strong portfolio in pain management and a recent entry into neuropsychiatry through the acquisition of Jornay PM [3].

Core Insights - Collegium Pharmaceutical reported $177.76 million in revenue for Q1 2025, a year-over-year increase of 22.7% [1] - The EPS for the same period was $1.49, compared to $1.45 a year ago, indicating a positive trend [1] - The revenue exceeded the Zacks Consensus Estimate of $172.45 million by 3.08%, and the EPS also surpassed the consensus estimate of $1.43 by 4.20% [1] Revenue Breakdown - Total product revenues for Belbuca were $51.66 million, slightly below the estimated $53.86 million, reflecting a 2% year-over-year increase [4] - Xtampza ER generated $47.64 million, exceeding the average estimate of $46.49 million, with a year-over-year change of 4% [4] - Jornay PM reported revenues of $28.54 million, closely matching the average estimate of $28.50 million [4] - Nucynta achieved $47.10 million in revenues, surpassing the average estimate of $42.13 million, marking a 4.3% year-over-year increase [4] - Symproic's revenues were $2.82 million, falling short of the average estimate of $3.25 million, representing a year-over-year decline of 14.7% [4] Stock Performance - Collegium Pharmaceutical's shares returned +2.6% over the past month, while the Zacks S&P 500 composite increased by +11.3% [3] - The stock currently holds a Zacks Rank 3 (Hold), suggesting it may perform in line with the broader market in the near term [3]

Core Viewpoint - Collegium Pharmaceutical reported quarterly earnings of $1.49 per share, exceeding the Zacks Consensus Estimate of $1.43 per share, and showing a slight increase from $1.45 per share a year ago, indicating a 4.20% earnings surprise [1][2] Financial Performance - The company achieved revenues of $177.76 million for the quarter ended March 2025, surpassing the Zacks Consensus Estimate by 3.08%, and up from $144.92 million in the same quarter last year [2] - Over the last four quarters, Collegium Pharmaceutical has exceeded consensus EPS estimates three times and has topped consensus revenue estimates three times as well [2] Stock Performance - Collegium Pharmaceutical shares have declined approximately 5.6% since the beginning of the year, compared to a decline of 4.3% for the S&P 500 [3] - The stock currently holds a Zacks Rank 3 (Hold), indicating it is expected to perform in line with the market in the near future [6] Future Outlook - The current consensus EPS estimate for the upcoming quarter is $1.61, with projected revenues of $181.28 million, and for the current fiscal year, the EPS estimate is $6.88 on revenues of $741.38 million [7] - The outlook for the Medical - Drugs industry, where Collegium operates, is favorable, ranking in the top 26% of over 250 Zacks industries, suggesting potential for outperformance [8]

Financial Data and Key Metrics Changes - The company reported a 23% year-over-year revenue growth, with net product revenues reaching $177.8 million [26][8] - GAAP net income was $2.4 million, a decrease from $27.7 million in the same quarter of the previous year, impacted by acquisition-related expenses [28] - Non-GAAP adjusted EBITDA was $95.2 million, up 3% year over year [28] - The cash position increased to $197.8 million, up $35 million from year-end [29] Business Line Data and Key Metrics Changes - The ADHD medicine Jornay generated $28.5 million in net revenue, with a 24% year-over-year growth in prescriptions [8][26] - The pain portfolio generated $149.2 million in sales, reflecting a 3% year-over-year growth, with all three pain medicines showing single-digit growth [9][22] - BELBUCA net revenue was $51.7 million, up 2% year over year; Xtampza net revenue was $47.6 million, up 4%; and Nucynta franchise net revenue was $47.1 million, also up 4% [27] Market Data and Key Metrics Changes - Jornay's market share in the long-acting branded methylphenidate market increased to 20.3%, up 6.4% year over year [18] - The overall ADHD market is growing at about 5% to 6% annually [48] Company Strategy and Development Direction - The company is focused on three strategic priorities: driving growth in Jornay, maximizing the pain portfolio's value, and strategically deploying capital to enhance shareholder value [5][11] - The company aims to diversify its portfolio through disciplined business development and has initiated a $25 million accelerated share repurchase program [11][31] Management's Comments on Operating Environment and Future Outlook - Management expressed confidence in achieving 2025 financial guidance and emphasized the importance of cash flow generation from the pain portfolio [33][29] - The company is well-positioned to leverage its strengths in responsible pain management while expanding into ADHD treatment [21][34] Other Important Information - The company announced leadership changes, including the retirement of founder Mike Heffernan as Chairman [7][10] - The company is committed to returning value to shareholders through share repurchases and has a strong track record in this regard [31][13] Q&A Session Summary Question: How will Journey scripts trend as the school year ends? - Management noted that there is typically a slowdown in scripts towards the end of the school year, followed by an acceleration in the back-to-school season [36][39] Question: Is there potential to apply JOURNEY PM technology to other compounds? - Management confirmed that discussions regarding the application of the technology to other compounds had occurred prior to the acquisition [40] Question: What is the appetite for business development deals? - Management indicated a disciplined approach to capital deployment, focusing on the right opportunities for business development while also prioritizing debt repayment and share repurchases [42][61] Question: What is the overall ADHD market growth? - The market is growing at about 5% to 6% annually, consistent over the past few years [48] Question: What is the breakdown of the prescriber base for Jornay? - The prescriber base is approximately 40% pediatricians, 40% neuropsychiatrists, and the remaining 20% consists of PCPs and mid-level providers [49] Question: Where is Jornay's market share growth coming from? - The majority of market share growth is coming from the movement away from generic immediate-release products [50]