Group 1 - Penumbra, Inc. will present at the Canaccord Genuity 45th Annual Growth Conference on August 12, 2025, at 12:30pm ET [1] - A webcast of the presentation will be available on the company's website for at least two weeks following the event [1] Group 2 - Penumbra, Inc. is a leading thrombectomy company focused on innovative technologies for medical conditions such as ischemic stroke and venous thromboembolism [2] - The company's portfolio includes computer assisted vacuum thrombectomy (CAVT) aimed at efficiently removing blood clots [2] - Penumbra supports healthcare providers in over 100 countries, enhancing patient outcomes and quality of life [2]

For the quarter ended June 2025, Penumbra (PEN) reported revenue of $339.46 million, up 13.4% over the same period last year. EPS came in at $0.86, compared to $0.64 in the year-ago quarter.The reported revenue represents a surprise of +3.54% over the Zacks Consensus Estimate of $327.85 million. With the consensus EPS estimate being $0.81, the EPS surprise was +6.17%.While investors closely watch year-over-year changes in headline numbers -- revenue and earnings -- and how they compare to Wall Street expect ...

Company Performance - Penumbra reported quarterly earnings of $0.86 per share, exceeding the Zacks Consensus Estimate of $0.81 per share, and up from $0.64 per share a year ago, representing an earnings surprise of +6.17% [1] - The company posted revenues of $339.46 million for the quarter ended June 2025, surpassing the Zacks Consensus Estimate by 3.54%, and an increase from $299.4 million year-over-year [2] - Over the last four quarters, Penumbra has consistently surpassed consensus EPS and revenue estimates [2] Stock Outlook - Penumbra shares have declined approximately 3.1% since the beginning of the year, while the S&P 500 has gained 8.6% [3] - The company's current Zacks Rank is 3 (Hold), indicating expected performance in line with the market in the near future [6] - The consensus EPS estimate for the upcoming quarter is $0.96 on revenues of $341.93 million, and for the current fiscal year, it is $3.72 on $1.35 billion in revenues [7] Industry Context - The Medical - Instruments industry, to which Penumbra belongs, is currently ranked in the bottom 37% of over 250 Zacks industries, suggesting potential challenges ahead [8] - Empirical research indicates a strong correlation between near-term stock movements and trends in earnings estimate revisions, which could impact Penumbra's stock performance [5]

Financial Data and Key Metrics Changes - Total revenue for Q2 2025 was $339.5 million, reflecting a year-over-year growth of 13.4% on a reported basis and 12.7% on a constant currency basis [7][19] - Gross margin was reported at 66%, an increase from 54.4% in Q2 2024, excluding a one-time inventory write-off of $33.4 million [22][24] - Operating income was $40.8 million, representing 12% of revenue, compared to an operating loss of $1.6 million in the same quarter last year [24][25] - Adjusted EBITDA was $61.4 million, or 18.1% of total revenue, compared to $13 million, or 4.3%, in Q2 2024 [25] Business Line Data and Key Metrics Changes - U.S. Thrombectomy revenue increased by 22.6% year-over-year to $188.5 million, driven by strong adoption of the CAVT portfolio [9][19] - Global thrombectomy business revenue grew to $230.3 million, a 13.1% increase reported and 12.6% in constant currency [21] - Revenue from the Embolization and Access business was $109.2 million, an increase of 13.9% reported and 12.8% in constant currency [22] Market Data and Key Metrics Changes - The U.S. region reported growth of 19.5%, primarily driven by the thrombectomy franchise [20] - International regions saw a decrease of 3.2% reported and 5.8% in constant currency, mainly due to a decline in China revenue [20] - Excluding China, international thrombectomy revenue grew by 14.4% compared to the same period last year [21] Company Strategy and Development Direction - The company is focused on continuous innovation and expanding the total number of patients treated globally with its technologies [7][8] - A separate peripheral embolization sales force has been established to enhance focus on thrombectomy and embolization, with over 50 new sales representatives added [12] - The company aims to achieve a gross margin profile of over 70% by 2026, with operating margin expansion expected to outpace gross margin expansion [10][24] Management's Comments on Operating Environment and Future Outlook - Management expressed optimism about easing headwinds in China, anticipating a return to growth in international regions [20] - The company is committed to running high-quality clinical studies to support its product offerings and market access initiatives [14] - Management highlighted the importance of the STORM PE trial, which could fundamentally shift patient treatment for pulmonary embolism [13][31] Other Important Information - The company ended Q2 2025 with cash, cash equivalents, and marketable securities of $424.6 million and no debt, an increase of $45.7 million sequentially [25] - The company is increasing its revenue guidance for 2025 to a range of $1.355 billion to $1.37 billion, representing 13% to 15% year-over-year growth [26] Q&A Session Summary Question: Importance of STORM PE study - Management emphasized that STORM PE is the first randomized study comparing anticoagulation and mechanical thrombectomy, which is significant for the field [31][33] Question: Update on Thunderbolt FDA review - Management stated that the FDA review process is thorough and as expected, and reiterated excitement about the Thunderbolt product [37][38] Question: Impact of Salesforce split on margins - Management clarified that the investment in the commercial team does not impact gross margin but may cause month-to-month variability in product mix [52] Question: Anticipated slowdown in specific divisions - Management noted that while the stroke market has shown softer growth, the company continues to gain market share [70] Question: Update on international markets, particularly China - Management indicated that while there were headwinds in China, recent orders have been filled, and the company is optimistic about future growth [79] Question: Market share in pulmonary embolism and DVT - Management believes they have gained significant market share in DVT, estimating over 50%, and have made substantial progress in the PE market [110]

Financial Data and Key Metrics Changes - Total revenue for the second quarter of 2025 was $339,500,000, representing a year-over-year growth of 13.4% on a reported basis and 12.7% on a constant currency basis [6][19] - Gross margin for the second quarter was 66%, up from 54.4% in the same quarter of 2024, which included a one-time $33,400,000 inventory write-off [22][23] - Operating income was $40,800,000, or 12% of revenue, compared to an operating loss of $1,600,000 for the same period last year [25][26] - Adjusted EBITDA was $61,400,000, or 18.1% of total revenue, compared to $13,000,000, or 4.3%, in the second quarter of the previous year [26] Business Line Data and Key Metrics Changes - U.S. Thrombectomy revenue increased by 22.6% year-over-year to $188,500,000, driven by a 42% growth in the USVTE franchise [8][19] - Global thrombectomy business revenue grew to $230,300,000, an increase of 13.1% reported and 12.6% in constant currency [21] - Revenue from the Embolization and Access business was $109,200,000, an increase of 13.9% reported and 12.8% in constant currency, primarily driven by U.S. Embolization sales [22] Market Data and Key Metrics Changes - The U.S. region reported growth of 19.5%, driven by the strong performance of the thrombectomy franchise [20] - International regions saw a decrease of 3.2% reported and 5.8% in constant currency, primarily due to a decline in China revenue [20] - Excluding the impact of the China region, international thrombectomy revenue grew by 14.4% compared to the same period last year [21] Company Strategy and Development Direction - The company is focused on continuous innovation and expanding the total number of patients treated globally with its technologies [6][7] - A separate peripheral embolization sales force has been established to enhance focus on thrombectomy and embolization, with over 50 new sales representatives added [11] - The company aims to achieve a gross margin profile of over 70% by 2026, with operating margin expansion expected to outpace gross margin expansion [9][24] Management's Comments on Operating Environment and Future Outlook - Management expressed optimism about easing headwinds in China, anticipating a return to growth across all international regions [20] - The company is committed to running high-quality clinical studies to support its product offerings and market access initiatives [12][17] - Management highlighted the importance of the STORM PE trial, which is expected to provide significant evidence for the treatment of pulmonary embolism [12][34] Other Important Information - The company ended the second quarter with cash, cash equivalents, and marketable securities of $424,600,000 and no debt, reflecting strong operating profitability [26] - Due to outperformance in the second quarter, the company increased its revenue guidance for 2025 to a range of $1,355,000,000 to $1,370,000,000, representing 13% to 15% year-over-year growth [27] Q&A Session Summary Question: Importance of STORM PE study - Management emphasized that STORM PE is the first randomized study comparing anticoagulation and mechanical thrombectomy, which is significant for the field [32][34] Question: Update on Thunderbolt FDA review - Management stated that the FDA review process is thorough and ongoing, and they remain excited about the product's potential impact [38][39] Question: Impact of Salesforce split on margins - Management clarified that the investment in the commercial team does not impact gross margins but is expected to support long-term margin goals [52][54] Question: Anticipated slowdown in U.S. thrombectomy business - Management acknowledged a potential deceleration in the stroke market but remains optimistic about continued growth in the thrombectomy business [48][72] Question: International market performance and China - Management noted that international markets are beginning to show signs of recovery, particularly with the launch of new products [80][82]

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2025 (State or other jurisdiction of incorporation or organization) Delaware 05-0605598 (I.R.S. Employer Identification No.) One Penumbra Place OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from_____ to _____ Commis ...

Exhibit 99.1 Penumbra, Inc. Reports Second Quarter 2025 Financial Results ALAMEDA, Calif., July 29, 2025 /PRNewswire/ -- Penumbra, Inc. (NYSE: PEN), the world's leading thrombectomy company, today reported financial results for the second quarter ended June 30, 2025. Second Quarter 2025 Financial Results Total revenue increased to $339.5 million for the second quarter of 2025 compared to $299.4 million for the second quarter of 2024, an increase of 13.4%, or 12.7% in constant currency . The United States re ...

ALAMEDA, Calif., July 29, 2025 /PRNewswire/ -- Penumbra, Inc. (NYSE: PEN), the world's leading thrombectomy company, today reported financial results for the second quarter ended June 30, 2025. Revenue of $339.5 million in the second quarter of 2025, an increase of 13.4% or 12.7% in constant currency1, compared to the second quarter of 2024. U.S. Thrombectomy revenue of $188.5 million in the second quarter of 2025, an increase of 22.6% compared to the second quarter of 2024. U.S. VTE revenue increased 42% c ...

Have you been searching for a stock that might be well-positioned to maintain its earnings-beat streak in its upcoming report? It is worth considering Penumbra (PEN) , which belongs to the Zacks Medical - Instruments industry.This medical device maker has seen a nice streak of beating earnings estimates, especially when looking at the previous two reports. The average surprise for the last two quarters was 16.18%.For the last reported quarter, Penumbra came out with earnings of $0.83 per share versus the Za ...

Core Viewpoint - Wall Street anticipates a year-over-year increase in earnings for Penumbra, with a focus on how actual results compare to estimates, which could significantly impact the stock price [1][2]. Earnings Expectations - Penumbra is expected to report quarterly earnings of $0.81 per share, reflecting a year-over-year increase of +26.6% [3]. - Revenue projections stand at $327.85 million, indicating a growth of 9.5% compared to the same quarter last year [3]. Estimate Revisions - The consensus EPS estimate has remained unchanged over the last 30 days, suggesting stability in analysts' assessments [4]. - A positive Earnings ESP of +1.28% indicates that analysts have recently become more optimistic about Penumbra's earnings prospects [12]. Earnings Surprise Prediction - The Zacks Earnings ESP model compares the Most Accurate Estimate to the Zacks Consensus Estimate, with a positive reading suggesting a likely earnings beat [8][10]. - Stocks with a positive Earnings ESP and a Zacks Rank of 1, 2, or 3 have historically produced positive surprises nearly 70% of the time [10]. Historical Performance - In the last reported quarter, Penumbra exceeded expectations by delivering earnings of $0.83 per share against an estimate of $0.66, resulting in a surprise of +25.76% [13]. - The company has beaten consensus EPS estimates in all of the last four quarters [14]. Conclusion - Penumbra is positioned as a strong candidate for an earnings beat, but investors should consider other influencing factors before making investment decisions [17].