Core Insights - AlphaMedix™ (212Pb-DOTAMTATE) achieved all primary efficacy endpoints in the ALPHAMEDIX-02 phase 2 study, demonstrating significant clinical benefits for patients with gastroenteropancreatic neuroendocrine tumors (GEP-NETs) [1][2][6] - The study showed clinically meaningful overall response rates (ORR) and prolonged clinical benefits in both peptide receptor radionuclide therapy (PRRT)-naïve and PRRT-exposed patients [1][2][6] - AlphaMedix™ has a manageable safety profile, consistent across both patient cohorts [1][3] Study Details - The ALPHAMEDIX-02 study is a phase 2, open-label, multicenter trial evaluating the efficacy and safety of AlphaMedix™ in patients with unresectable or metastatic GEP-NETs [4] - The study included two cohorts: 35 PRRT-naïve patients and 26 PRRT-exposed patients, with the latter having progressive disease after receiving up to four doses of 177Lu-DOTATATE [4] - AlphaMedix™ was administered at a dosage of 67.6 μCi/kg every eight weeks for up to four cycles, with primary endpoints including ORR and safety, and secondary endpoints including progression-free survival (PFS) and overall survival (OS) [4] Industry Context - The results from the ALPHAMEDIX-02 study highlight the potential of lead-212-based radiopharmaceuticals in addressing unmet medical needs for patients with GEP-NETs [2][3] - AlphaMedix™ was granted Breakthrough Therapy Designation by the FDA in February 2024, recognizing its potential clinical benefits for PRRT-naïve patients with unresectable or metastatic GEP-NETs [2] - The study results will be presented at the 2025 European Society for Medical Oncology (ESMO) Congress and will inform discussions with health authorities regarding future regulatory approvals [3][6] Company Background - Orano Med is a clinical-stage biotechnology company focused on developing targeted therapies against cancer using lead-212, an alpha-emitting radioisotope [8] - Sanofi is an R&D-driven biopharma company committed to improving healthcare through innovative therapies, including those for difficult-to-treat cancers [9]

Novavax (NASDAQ:NVAX) said that it has officially transferred the marketing authorization for its COVID-19 vaccine, Nuvaxovid, to Sanofi (NASDAQ:SNY) within the European Union. As a result of this transfer, Novavax received a milestone payment of $25M. This move allows Sanofi ...

We revisit Sanofi (NASDAQ: SNY ) ( OTCPK:SNYNF ) ( GCVRZ ) after our downgrade in early May 2024, a move that has so far been validated by the market, with the S&P 500 delivering double-digitBuy-side hedge professionals conducting fundamental, income oriented, long term analysis across sectors globally in developed markets. Please shoot us a message or leave a comment to discuss ideas.DISCLOSURE: All of our articles are a matter of opinion, informed as they might be, and must be treated as such. We take no ...

Group 1 - The article revisits Sanofi after a downgrade in early May 2024, which has been validated by market performance [1] - The S&P 500 has delivered double-digit returns since the downgrade, indicating a broader market trend [1] Group 2 - The analysis is conducted by buy-side hedge professionals focusing on fundamental, income-oriented, long-term analysis across global developed markets [1]

Sanofi (NASDAQ:SNY) is one of the Best and Cheap Stocks to Buy Right Now. On September 24, Sanofi (NASDAQ:SNY) announced an additional $625 million investment in Sanofi Ventures to boost the fund’s total assets to over $1.4 billion. Management noted that this investment supports the venture’s long-term focus on biotech and digital health startups. Sanofi (NASDAQ:SNY) founded Sanofi Ventures in 2012; which has invested more than $800 million in around 70 companies internationally. The venture invests in co ...

In this article, we will look at the 11 Best and Cheap Stocks to Buy Right Now.On October 3, Wharton professor and WisdomTree Chief Economist Jeremy Siegel joined CNBC for an interview to discuss the current and near-future outlook for the stock market. He noted that the upward trend in the market remains intact, despite concerns about the government shutdown. Siegel highlighted that he does not see the shutdown derailing the market unless it lasts longer than 2 weeks, which he believes could hurt consumer ...

HSBC sets a price target of $70 for Novo Nordisk (NYSE:NVO), indicating a potential 18.3% increase.The stock experienced a notable 6% increase following an agreement between Pfizer and the Trump administration, hinting at a positive outlook for pharmaceutical companies.President Trump's tariff threats could impact foreign pharmaceutical companies, but deals like Pfizer's offer a grace period, benefiting companies like Novo Nordisk.Novo Nordisk (NYSE:NVO) is a leading global healthcare company based in Denma ...

Core Insights - Sanofi (NASDAQ:SNY) is recognized as one of the 12 Best Widow and Orphan Stocks to Buy according to analysts, indicating significant upside potential for investors [1] Company Performance and Market Position - Berenberg has reaffirmed its Buy rating on Sanofi with a price target of EUR110.00, highlighting better returns from the company's medication pipeline [2] - Analysts estimate Sanofi's market capitalization at $111.7 billion, with stock price predictions ranging from $53 to $69, while the current trading price is $45.65 [2] Pipeline and Future Prospects - Sanofi's 2020 pipeline cohort is projected to yield a 10% return, with potential for significant growth if peak sales of key drugs like amlitelimab and frexalimab double, or if duvakitug enters Phase 3 [3] Pricing Strategy and Patient Access - Sanofi announced a new initiative to cap the cost of any insulin product at $35 per month for U.S. patients with a valid prescription, regardless of insurance status, which aims to enhance patient access [4] - This pricing strategy reflects Sanofi's commitment to expanding its pipeline momentum and improving accessibility for patients in the United States [4] Company Overview - Sanofi is engaged in researching, developing, manufacturing, and marketing pharmaceutical solutions globally, with a focus on various therapeutic areas including immunology, neurology, oncology, rare diseases, and vaccines [5]

Key Takeaways Sanofi dropped KT-474 but advanced Kymera's IRAK4 degrader KT-485 into clinical development.Gilead signed a $750M deal with Kymera to develop CDK2-targeting molecular glue degraders.KT-621 showed strong phase I results in atopic dermatitis, with phase 2b trials set for 2025-26.It has been a roller coaster ride for Kymera Therapeutics (KYMR) stock this year.  This clinical-stage biotechnology company is pioneering the field of targeted protein degradation (TPD) to develop drugs for various immu ...

每经AI快讯，10月1日，美股医药股逆势上涨，阿斯利康涨超6%，赛诺菲安万特、葛兰素史克涨近 4%，礼来、渤健公司、诺和诺德、默沙东涨近3%，辉瑞涨超2%。 ...