AC Immune Initiates Phase 1 Clinical Trial of NLRP3 Inhibitor ACI-19764 is an orally available highly brain-penetrant small molecule NLRP3 inhibitorNLRP3 inhibitors are a major new class of compounds linked to a broad spectrum of inflammatory conditions including both metabolic and neurological diseasesACI-19764 is an important addition to AC Immune’s growing small molecule pipelinePhase 1 results in healthy volunteers are expected in H2 2026 Lausanne, Switzerland, February 24, 2026 -- AC Immune SA (NASDAQ ...

Core Insights - Oroco Resource Corp. has mobilized a diamond drill rig to its Santo Tomás copper project in northwestern Mexico to commence drilling aimed at upgrading mineral resource classifications in the project's South Zone [1][2] Company Developments - The mobilization marks the practical start of Oroco's Phase 2 on-site work program, following recent financing led by Canaccord Genuity, with initial work focusing on infill and confirmation drilling to enhance geological and grade models [2] - Additional drills will be added as necessary to support the drilling efforts [2] Project Engineering and Risk Management - Concurrently with resource-classification drilling, Oroco will conduct complementary Pre-Feasibility Study (PFS) programs to advance project engineering and mitigate technical risks, including hydrogeological, geotechnical, and metallurgical studies [3][7] - Hydrogeological work will involve baseline data collection and targeted testing for water management planning [7] - Geotechnical efforts will include systematic logging of drill core and collection of parameters relevant to pit slope and infrastructure design [7] - Metallurgical studies will focus on sample collection to support variability and process-response testing [7] Project Background - The Santo Tomás Project is significant for its porphyry copper mineralization, previously defined by extensive exploration from 1968 to 1994, and has undergone a Phase 1 drill program since 2021, totaling 48,481 meters in 76 diamond drill holes [5] - The project area has been rationalized, with the company holding a net 87.0% interest in the central concessions covering 1,173 hectares [4]

Palo Alto, California, Feb. 24, 2026 (GLOBE NEWSWIRE) -- Mobilicom Limited (Nasdaq: MOB, MOBBW) (“Mobilicom” or the “Company”), a provider of cybersecurity and robust solutions for drones and robotics, today announced that it will attend Enforce Tac 2026, Germany’s prominent trade fair for security and defense, being held February 23–25, 2026, in Nuremberg, Germany. Mobilicom’s participation at Enforce Tac 2026 reflects the Company’s strategic commitment to expanding its footprint across the European Union— ...

NEW YORK, Feb. 24, 2026 (GLOBE NEWSWIRE) -- OTC Markets Group Inc. (OTCQX: OTCM), operator of regulated markets for trading 12,000 U.S. and international securities, today announced GR Silver Mining Ltd. (TSX-V: GRSL; OTCQX: GRSLF), a Canadian-based, Mexico-focused mineral exploration company, has qualified to trade on the OTCQX® Best Market. GR Silver Mining Ltd. upgraded to OTCQX from the OTCQB® Venture Market. GR Silver Mining Ltd. begins trading today on OTCQX under the symbol “GRSLF.” U.S. investors ca ...

― Mean absolute fetal hemoglobin (HbF) increased by 12.2% (from 7.1% to 19.3%) at Week 12 (n=12), representing a rapid, robust, and clinically relevant response, with progression toward pan-cellular HbF induction as F-cells increased from 31% to 63% ― ― 7 of 12 patients (58%) achieved absolute HbF levels ≥20%; all patients achieved at least a 6.5% absolute increase in HbF ― ― Improvements in markers of hemolysis, improved erythropoiesis, and a >1 g/dL increase in total hemoglobin ― ― 7 of 12 patients (58%) ...

Core Insights - Shoals Technologies Group and ON.energy have entered into an agreement to deploy multiple gigawatts of power systems for the AI data center market, addressing the growing demand for reliable power solutions in this sector [1][3]. Company Overview - Shoals Technologies Group is a leading manufacturer of advanced electrical infrastructure solutions, focusing on mission-critical applications such as utility-scale solar, battery storage, and data center power systems. The company has been recognized for its innovative technologies that enhance installation efficiency and system performance since its founding in 1996 [6]. Industry Context - The AI and cloud computing sectors are driving significant growth in data center energy demand, necessitating improvements in power reliability, build speed, and operational continuity [3][4]. - Data centers require power architectures that are predictable under stress and can be deployed quickly, which is essential for maintaining uptime and transforming data centers into grid assets as they expand [4]. Technological Collaboration - The partnership combines ON.energy's medium-voltage AI UPS™ platform with Shoals' DC Recombiner, creating a scalable solution for resilient backup power that enhances data center reliability [4][5]. - ON.energy contributes its expertise in medium-voltage UPS architecture and utility-scale storage, while Shoals adds its engineering capabilities and prefabricated designs to reduce technical and financial risks [5]. Manufacturing Expansion - Shoals is expanding its production capacity with a new manufacturing campus of approximately 638,000 square feet in Portland, TN, to support the increasing energy demands of AI and cloud computing [4].

Rebrands to Cipher Digital to Reflect Strategic Shift Toward HPC Divested 49% Stake in Alborz, Bear, and Chief Mining Sites Secured Full Funding for Existing Data Center Developments Through High-Yield Bond Offerings Data Center Development on Track at Barber Lake and Black Pearl NEW YORK, Feb. 24, 2026 (GLOBE NEWSWIRE) -- Cipher Digital Inc. (NASDAQ: CIFR) (“Cipher” or the “Company”) today announced its fourth quarter and full year 2025 financial results, with an update on its operations and business strat ...

WAYNE, Pa., Feb. 24, 2026 (GLOBE NEWSWIRE) -- Aclaris Therapeutics, Inc. (NASDAQ: ACRS), a clinical-stage biopharmaceutical company focused on developing novel product candidates for immuno-inflammatory diseases, today announced that it has initiated a placebo-controlled Phase 1b proof-of-concept (POC) trial of ATI-052, the Company’s potential best-in-class investigational bispecific anti-TSLP/IL-4Rα antibody, in asthma. This announcement follows the recent initiation of the Company’s Phase 1b POC trial of ...

Core Insights - Enviri Corporation reported a consolidated loss from continuing operations of $86 million in Q4 2025, with revenues totaling $556 million, reflecting a slight decrease from $559 million in Q4 2024 [1][4][5] - The company experienced a full-year revenue of $2.24 billion in 2025, down from $2.34 billion in 2024, with a GAAP consolidated loss from continuing operations of $160 million [8][10][9] - The company is on track to complete the $3 billion sale of Clean Earth in mid-2026, which is expected to unlock significant value for shareholders [3][19] Financial Performance - Q4 2025 adjusted EBITDA was $70 million, consistent with Q4 2024, while the adjusted diluted loss per share from continuing operations was $0.17 compared to $0.04 in Q4 2024 [2][4][5] - For the full year 2025, adjusted EBITDA totaled $275 million, down from $318 million in 2024, with the adjusted diluted loss per share increasing to $0.60 from $0.09 [10][11][8] - The company’s operating income from continuing operations was a loss of $33 million in Q4 2025, an improvement from a loss of $62 million in Q4 2024 [4][7] Segment Performance - Harsco Environmental reported revenues of $257 million in Q4 2025, a 7% increase from Q4 2024, with an adjusted EBITDA margin of 18.7% [12][13] - Clean Earth generated $244 million in revenues in Q4 2025, a slight increase from $241 million in Q4 2024, with an adjusted EBITDA margin of 15.6% [14][13] - Harsco Rail saw a significant revenue decline of 28% to $56 million in Q4 2025, with an adjusted EBITDA loss of $4 million [15][13] Cash Flow and Outlook - Net cash provided by operating activities was $38 million in Q4 2025, slightly up from $36 million in Q4 2024, while adjusted free cash flow decreased to $6 million from $8 million [16][17] - The 2026 outlook anticipates adjusted EBITDA for New Enviri to be approximately $140 million, modestly below 2025 levels due to weaker demand in Harsco Rail [19][20] - Harsco Environmental's adjusted EBITDA is expected to improve slightly, while Harsco Rail's adjusted EBITDA is projected to be negative due to lower demand and manufacturing inefficiencies [21][20]

Highlights: CS25-063: 13 separate intervals, including: 75.4 m at 1.67% Li2O; and21.8 m at 1.12% Li2O.Mineralization encountered extend the boundary of the known Mineralized Zone to the west. CS25-064: Nine (9) separate intervals, including: 166.7 m at 1.47% Li2O. CS25-072: Eight (8) separate intervals, including: 82.1 m at 1.71% Li2O;109.5 m at 1.67% Li2O; and121.6 m at 1.45% Li2O. CS25-073: Five (5) separate intervals, including: 170.2 m at 1.99% Li2O, including 40.1 m at 2.89% Li2O;74.2 m at 0.94% Li2O;7 ...