证券代码：300633 证券简称：开立医疗 公告编号：2025-033 深圳开立生物医疗科技股份有限公司 关于 2025 年半年度计提资产减值准备及核销资产的公告 本公司及董事会全体成员保证信息披露内容的真实、准确和完整，没有虚假 记载、误导性陈述或重大遗漏。 深圳开立生物医疗科技股份有限公司（以下简称"公司"）根据《企业会计 准则》及《深圳证券交易所上市公司自律监管指引第 2 号—创业板上市公司规范 运作》等相关规定，对公司及下属子公司进行资产减值测试。以 2025 年 6 月 30 日为基准日，对合并财务报表范围内相关资产计提资产减值准备，对部分资产予 以核销。现将具体情况公告如下： 一、本次计提资产减值准备情况概述 根据《企业会计准则》及公司会计政策等相关规定，为真实、准确反映公 司截止 2025 年 6 月 30 日的资产状况和财务状况，公司对合并报表范围内可能出 现减值迹象的各类资产进行了减值测试，根据测试结果，基于谨慎性原则，公司 拟对报告期末可能发生资产减值损失的资产计提减值准备。 二、本次计提资产减值准备的资产范围和总金额 公司及下属子公司对 2025 年 6 月 30 日存在可能发生减值迹象 ...

证券代码：300633 证券简称：开立医疗 公告编号：2025-032 深圳开立生物医疗科技股份有限公司 2025 年半年度募集资金存放与使用情况专项报告 本公司及董事会全体成员保证信息披露内容的真实、准确和完整，没有虚假 记载、误导性陈述或重大遗漏。 一、募集资金基本情况 （一）实际募集资金金额及资金到账情况 经中国证券监督管理委员会证监许可〔2021〕668 号文核准，并经深圳证券 交易所同意，本深圳开立生物医疗科技股份有限公司（以下简称"公司"）由主 承销商长城证券股份有限公司（以下简称"长城证券"）采用定向发行方式，向 特定对象非公开发行股份人民币普通股（A 股）股票 27,851,745 股，发行价为每 股人民币 27.79 元，共计募集资金 773,999,993.55 元，坐扣承销费用 1,886,792.45 元后的募集资金为772,113,201.10元，其中245,167,501.10元已由长城证券于2021 年 12 月 21 日汇入公司在中国工商银行股份有限公司南山支行开立的账号为 4000020319200789913 的人民币账户，526,945,700.00 元已由长城证券于 2 ...

本公司及董事会全体成员保证信息披露内容的真实、准确和完整，没有虚假 记载、误导性陈述或重大遗漏。 深圳开立生物医疗科技股份有限公司 2025 年半年度报告及其摘要于 2025 年 8 月 22 日在中国证监会指定的创业板信息披露网站巨潮资讯网（http://www.c ninfo.com.cn/）上披露，请投资者注意查阅。 特此公告。 深圳开立生物医疗科技股份有限公司董事会 证券代码：300633 证券简称：开立医疗 公告编号：2025-029 深圳开立生物医疗科技股份有限公司 关于 2025 年半年度报告披露的提示性公告 2025 年 8 月 21 日 ...

证券代码：300633 证券简称：开立医疗 公告编号：2025-031 深圳开立生物医疗科技股份有限公司 第四届监事会第八次会议决议公告 本公司及监事会全体成员保证信息披露内容的真实、准确和完整，没有虚假 记载、误导性陈述或重大遗漏。 一、监事会会议召开情况 2025 年 8 月 20 日，深圳开立生物医疗科技股份限公司（以下简称"公司"） 第四届监事会第八次会议在深圳市光明区光电北路 368 号开立医疗大厦一楼会 议室召开。本次会议由监事会主席陈欣主持。应出席监事 3 名，实际出席监事 3 名。符合《公司章程》规定的法定人数，本次监事会会议决议合法有效。 二、监事会会议审议情况 经与会监事审议表决，一致通过了如下决议： 1、审议通过《关于公司 2025 年半年度报告及其摘要的议案》 经审核，监事会认为：董事会编制和审核公司 2025 年半年度报告的程序符 合法律、行政法规和中国证监会的规定，报告内容真实、准确、完整地反映了上 市公司的实际情况，不存在任何虚假记载、误导性陈述或者重大遗漏。 具体内容详见公司在中国证监会指定的创业板信息披露网站巨潮资讯网披 露的《2025 年半年度报告》以及《2025 年半年度 ...

证券代码：300633 证券简称：开立医疗 公告编号：2025-030 一、董事会会议召开情况 2025 年 8 月 20 日，深圳开立生物医疗科技股份有限公司（以下简称"公司"） 第四届董事会第九次会议以现场和通讯表决相结合的方式在深圳市光明区光电 北路 368 号开立医疗大厦一楼会议室召开。本次会议已于 2025 年 8 月 11 日以电 话、电子邮件等方式通知全体董事。 本次会议应出席董事 7 人，实际出席董事 7 人，会议由董事长陈志强先生主 持，符合《公司章程》规定的法定人数，会议的召集、召开符合《公司法》和《公 司章程》的有关规定。 二、董事会会议审议情况 经与会董事投票表决，审议通过了如下决议： 1、审议通过《关于公司 2025 年半年度报告及其摘要的议案》 具体内容详见公司在中国证监会指定的创业板信息披露网站巨潮资讯网披 露的《2025 年半年度报告》以及《2025 年半年度报告摘要》。 深圳开立生物医疗科技股份有限公司 第四届董事会第九次会议决议公告 本公司及董事会全体成员保证信息披露内容的真实、准确和完整，没有虚假 记载、误导性陈述或重大遗漏。 本议案中的财务报告部分已经公司董事会审计委员 ...

深圳开立生物医疗科技股份有限公司 2025 年半年度报告全文 深圳开立生物医疗科技股份有限公司 2025 年半年度报告 2025 年 8 月 1 深圳开立生物医疗科技股份有限公司 2025 年半年度报告全文 第一节 重要提示、目录和释义 公司董事会、监事会及董事、监事、高级管理人员保证半年度报告内容的真实、准 确、完整，不存在虚假记载、误导性陈述或者重大遗漏，并承担个别和连带的法律责任。 公司负责人陈志强、主管会计工作负责人罗曰佐及会计机构负责人(会计主管人员)徐 婷婷声明：保证本半年度报告中财务报告的真实、准确、完整。 所有董事均已出席了审议本次半年报的董事会会议。 本报告中所涉及的未来计划、发展战略等前瞻性描述不构成公司对投资者的实质承 诺，能否实现取决于宏观经济、市场状况变化等多种因素，存在不确定性，并提请投资者 注意公司在经营过程中面临的以下风险： 1、研发风险 医疗器械行业是国家重点监管行业，行业受医疗卫生政策的影响较大。随着国内医疗 体制改革的不断深化，医疗器械的集采比例逐渐增加，对国内医疗器械的产品单价、毛利 率带来负面影响。 5、营销团队稳定性风险 近几年来，公司的研发费用占当期营业收入的比例 ...

Group 1 - The medical sector is active, with the largest medical ETF in A-shares (512170) seeing a price increase of over 1% and a trading volume of 322 million yuan, ranking first among similar ETFs [1] - Major stocks such as Meihua Medical, Kaili Medical, and Huaxi Biological have shown significant gains, with Meihua Medical hitting a 20% limit up [1] - The top-weighted stocks, Mindray Medical and United Imaging, both rose over 3% [1] Group 2 - Gilead Sciences announced a 100% prevention efficacy for its HIV-1 capsid inhibitor lenacapavir in phase 3 clinical trials [3] - Major companies like Midea and Haier are accelerating their investments in the healthcare sector, focusing on medical imaging and low-temperature storage [3] - The medical device sector is benefiting from policy support and innovation, with a focus on high-certainty performance in specific sub-sectors during the mid-year reporting period [3] Group 3 - The National Healthcare Security Administration has published an initial review list for innovative drugs, indicating a significant increase in the number of drug generic names passing initial review compared to 2024 [3] - The "anti-involution" principle in centralized procurement is established, leading to a gradual easing of policy impacts, which may improve profitability in the medical device sector [3] - The in-vitro diagnostics market is seeing accelerated market share growth for domestic leaders, with high-value consumables expected to experience a recovery in performance and valuation due to eased procurement policies [3]

Group 1 - The medical sector is active, with the largest medical ETF in A-shares (512170) seeing a price increase of over 1% and a trading volume of 322 million yuan, ranking first among similar ETFs [1] - The latest fund size of the medical ETF is 27.36 billion yuan, with significant gains in constituent stocks such as Meihao Medical, Kaili Medical, and Huaxi Biological, where Meihao Medical hit a 20% limit up [1] - Major weighted stocks like Mindray Medical and United Imaging also experienced gains exceeding 3% [1] Group 2 - Gilead Sciences announced a 100% prevention efficacy of its HIV-1 capsid inhibitor lenacapavir in phase 3 clinical trials [3] - Major companies like Midea and Haier are accelerating their investments in the healthcare sector, focusing on medical imaging and low-temperature storage [3] - The medical device sector is benefiting from policy support and innovation, with a focus on high-certainty performance in specific sub-sectors during the mid-year reporting period [3] Group 3 - The National Healthcare Security Administration has published an initial review list for innovative drugs, indicating a significant increase in the number of drug generic names passing initial review compared to 2024 [3] - The "anti-involution" principle in centralized procurement is established, leading to a gradual easing of policy impacts, which may improve profitability in the medical device industry [3] - The domestic leading companies in the in-vitro diagnostics field are rapidly increasing their market share, and high-value consumables are expected to see a recovery in performance and valuation due to the easing of centralized procurement policies [3]

Core Insights - The Chinese AI + medical imaging industry is rapidly developing, with a market size projected to reach 7.6 billion yuan in 2024, representing a year-on-year growth of 109.94% [1][11] - AI technology is capable of quickly identifying small lesions from vast amounts of imaging data, facilitating precise early screening for various diseases and providing significant diagnostic support for doctors [1][11] - The product types in AI medical imaging are diversifying, with a trend towards integrated hardware and software solutions becoming the preferred choice for medical institutions [1][11] Industry Overview - AI + medical imaging refers to the use of AI technologies, such as deep learning and computer vision, to analyze and process medical images (e.g., X-rays, CT scans, MRIs, ultrasounds) to assist doctors in disease diagnosis, treatment planning, and prognosis evaluation [1][4] - The core function includes auxiliary diagnosis, treatment planning, prognosis assessment, and early detection screening [1][4] Industry Value Chain - The upstream of the AI + medical imaging industry includes medical imaging equipment, chips, servers, storage devices, imaging acquisition and processing software, cloud services, network operation platforms, and algorithm and data platforms [4] - The midstream involves the development and manufacturing of AI + medical imaging technologies, while the downstream primarily serves medical institutions, health check centers, and research and educational institutions [4] Market Size - The market size of the Chinese medical imaging equipment industry is expected to reach 69.3 billion yuan in 2024, with a year-on-year growth of 9.83% [6] Relevant Policies - The Chinese government has issued several policy documents to support and regulate the development of the AI + medical imaging industry, emphasizing the optimization of medical device standards and the establishment of standardization organizations for AI and medical robotics [8][10] - The policies aim to accelerate approval processes, enhance innovation ecosystems, and improve international competitiveness [8][10] Key Companies and Performance - Major companies in the AI + medical imaging sector include United Imaging Healthcare, Wandong Medical, Mindray, and Shukun Technology, each leveraging unique strengths in hardware and AI software integration [13][15] - United Imaging Healthcare reported a revenue of 10.3 billion yuan in 2024, a decrease of 9.73% year-on-year, while its R&D investment increased by 17.84% to 2.261 billion yuan [15] - Shukun Technology focuses on providing comprehensive AI solutions for medical institutions, achieving significant market penetration with its innovative products [17] Industry Development Trends 1. The industry is expected to advance towards multi-modal data integration and deep learning, enhancing diagnostic accuracy and personalized treatment [20] 2. Applications of AI in medical imaging will expand from auxiliary diagnosis to full-process management, improving service efficiency and quality [21] 3. Regulatory frameworks will evolve to include data privacy protections and accountability mechanisms for AI-generated content [22]

Core Insights - The Shenzhen-Europe Railway Express has celebrated its 5th anniversary, having operated 859 trains and transported 57,500 tons of goods valued at 21.16 billion yuan [1] - Shenzhen Customs has implemented innovative regulatory models and optimized customs processes to enhance the quality and efficiency of the Shenzhen-Europe Railway Express [1][2] Group 1: Operational Achievements - Over the past five years, the Shenzhen-Europe Railway Express has expanded its operational capacity, now featuring 27 regular routes covering 47 countries and regions, including major cities like Duisburg, Prague, Milan, and Moscow [1] - The railway service has significantly improved transportation efficiency, reducing shipping time to Europe from 30-40 days by sea to approximately 20 days by rail [1] Group 2: Supportive Measures by Shenzhen Customs - Shenzhen Customs has introduced various supportive measures, including the establishment of green channels and all-time appointment inspections, allowing for immediate customs clearance upon arrival [2] - The customs authority has also launched customized trains for high-value goods, such as cross-border e-commerce products, ensuring high stability and timeliness in exports [2] - Additional policies like railway fast passage, manifest consolidation, and return freight deductions have been implemented to facilitate smoother operations for the railway express [2]