证券研究报告 | 公司深度报告 2025 年 07 月 21 日 开立医疗（300633.SZ） 超声+软镜国产龙头，创新智造引领医疗"芯"时代 消费品/生物医药 开立医疗作为国产医用超声+软镜双龙头，产品矩阵覆盖全面，技术积累深厚， 凭借研发突破加速进口替代，带动业绩快速增长，同时布局微创外科和心血管 领域，打开成长天花板。短期内随终端招采回暖业绩弹性有望释放，值得关注。 ❑ 超声基本盘稳固，内镜市占率稳步提升 公司超声业务保持行业品牌影响力，2024 年实现收入 11.83 亿元（-3.26%）， 全球市占前十、国产第二；内镜业务趋于稳定，2024 年收入 7.95 亿元 （-6.47%），近五年 CAGR 达 22.18%，营收占比 39.77%，国内市占第三， 仅次于奥林巴斯、富士，且随规模效益显现，内镜业务盈利能力凸显，带动 公司毛利优化。 ❑ 多产线亮点纷呈，超声、软镜冲击高端市场，微创外科+心血管介入发力在即 超声：公司是国内较早研发并掌握彩超设备和探头核心技术的企业，彩超技 术在国内同行业中处于领先地位。2025 年推出产科超声 AI 检测技术凤眼 ™S-Fetus，成为全球首个具备切面自动抓 ...

AI基金博时健康成长双周定期可赎回混合A（009468）披露2025年二季报，第二季度基金利润2696.99万元，加权平均基金份额本期利润0.0627元。报告期 内，基金净值增长率为7.62%，截至二季度末，基金规模为3.75亿元。 该基金属于偏股混合型基金，长期投资于医药医疗股票。截至7月18日，单位净值为0.96元。基金经理是陈西铭，目前管理3只基金近一年均为正收益。其 中，截至7月18日，博时健康生活混合A近一年复权单位净值增长率最高，达25.95%；博时医疗保健混合A最低，为11.62%。 基金管理人在二季报中表示，本季度医药行业表现有所回暖，尤其是创新药行业，表现较为突出。一方面，大体量向外授权持续落地，海外大药企扫货，带 来创新药公司管线重估；另一方面，国内政策持续支持鼓励，相关政策陆续落地，体现了监管自上而下对创新药行业的支持。在本季度，创新药板块普遍出 现重估行情，市场对大多数创新药公司进行了又一轮价值发现。我们仍然看好创新药板块行情，认为行情已从所有创新药公司普遍重估的第一阶段进入考验 实际兑现的第二阶段，真正能谈成好的 BD 合作、产品放量超预期的公司仍有望表现突出；此外，小部分遗珠也有待 ...

国联民生（601456）证券发布研报称，2025年6月海外对于医疗AI产品的投资热情活跃，医疗器械已透 露单笔融资金额前三中有两笔跟医疗AI有关，且均为医疗AI电子病历产品。AI不断赋能医疗场景，建 议关注医疗AI相关标的。2025年6月我国整体医疗设备招投标数据延续增长态势，随着医疗设备以旧换 新资金逐步到位，采购需求不断回暖，医学影像、基因测序仪和血液/腹膜透析设备招投标数据表现亮 眼，建议关注联影医疗、迈瑞医疗（300760）等医疗设备相关企业。 国联民生证券主要观点如下： 创新药为我国医疗健康6月融资热门赛道 2025年6月全球医疗健康领域共发生144件融资事件，已透露融资金额约达22亿美元(接近49%事件未透 露金额)。创新药为6月中国医疗健康融资热点。已透露单笔最大融资额(2亿元)分别为天辰生物、思璞锐 和柏全生物，分别致力于抗过敏、抗癌药物研发。 医疗设备招投标延续增长态势 医学影像、基因测序和血液/腹膜透析设备招投标保持高速增长。根据众成器械数据，2025年6月全国各 类器械招投标销售额分别为电子计算机断层扫描仪(CT)19亿元(yoy+63%)，磁共振15亿元(yoy+65%)， 超声14亿 ...

Core Viewpoint - The article discusses the performance and management of the Rongtong Health Industry Flexible Allocation Mixed Fund A/B, highlighting its net asset growth and the background of its fund manager, Wan Minyuan [1][2]. Fund Performance - As of June 30, 2025, the net assets of the Rongtong Health Industry Flexible Allocation Mixed Fund A/B reached 2.074 billion yuan, reflecting a 1.92% increase from the previous period [1]. - The fund's recent performance includes a 15.0% return over the last three months and a 19.86% return over the past year, with a cumulative return of 166.1% since inception [2]. Fund Manager Background - Wan Minyuan, the fund manager, holds a PhD in Biomedical Science from Sichuan University and has extensive experience in the investment sector, having worked at various securities firms and investment management companies since 2011 [1]. Fund Holdings - The top ten stock holdings of the fund include Yixin Tang, Aibo Medical, Sanyou Medical, Jianzhijia, Kaili Medical, Yangguang Nuohuo, Dongfang Biological, Puri Eye Care, Meihua Medical, and Meinian Health, with a combined holding percentage of 57.00% [2]. Company Overview - Rongtong Fund Management Co., Ltd. was established in May 2001 and is based in Shenzhen, focusing on capital market services, with a registered capital of 125 million yuan [2].

Core Viewpoint - The 2025 Global MedTech Conference showcased advancements in medical technology innovation and clinical application, highlighting the achievements of Chinese medical technology companies and teams in key areas such as equipment, service systems, and research transformation [2][23]. Summary by Categories 2025 Global Medical Technology Innovation Awards - The awards included three categories: Technology Innovation Award, Innovation Service Award, and Innovation Transformation Award, recognizing significant contributions from Chinese medical technology enterprises [2][23]. Technology Innovation Award Winners - **Kaili Medical**: Recognized for breakthroughs in ultrasound endoscopy, including the EG-UR5 ultrasound endoscope, which received EU CE certification in 2019 and NMPA approval in 2021, making China the second country with independent intellectual property rights in this technology [8]. - **SinoVision**: Awarded for the OmegaCT One, the world's first ultra-large aperture whole-body spiral CT system, which provides new 3D spatial anatomical information for various medical disciplines [10]. - **Karl Storz**: Lauded for the IMAGE1 S Rubina imaging system, which integrates 4K/3D/NIR fluorescence imaging technology, enhancing surgical precision and anatomical recognition [11]. - **Zhongke Ruiyi**: Acknowledged for developing an intelligent platform for brain health diagnosis and intervention, with over 10 products and 7 NMPA registrations [12]. - **Hua Rui Bo Shi**: Recognized for the Infivision 1900, the world's first commercial 3D electrical impedance imaging device for non-invasive lung monitoring [14]. Innovation Service Award Winners - **Tonghe Litai**: Provided comprehensive preclinical research services, assisting in the successful market registration of innovative medical products [16]. - **Xiyi Medical**: Offered one-stop services for medical device internationalization, helping over 80 projects achieve successful overseas market entry [18]. - **Tsinghua Innovation Star**: Supported medical technology enterprises through a full-process ecosystem service, fostering innovation and commercialization [19]. Innovation Transformation Award Winners - **Lu Hongzhou**: Recognized for developing non-contact health monitoring technologies, including the P20i device for multi-parameter monitoring [20]. - **Wang Yu**: Awarded for creating the world's first intelligent fracture reduction robot, enhancing surgical precision and efficiency [21]. - **Xu Boling**: Acknowledged for leading the development of the MoyoAssist® artificial heart, the first of its kind approved in China, addressing critical care needs [22]. Conclusion - The awarded companies and individuals demonstrated significant advancements in medical technology, showcasing China's progress towards a more systematic, pragmatic, and globally aware development phase in the industry [23].

Investment Rating - Industry investment rating: Stronger than the market (maintained) [1][23] Core Viewpoints - The demand for medical equipment bidding continues to be strong, with a significant recovery in procurement activities expected to improve company financial performance [3][5] - The overall market size for medical device bidding in China exceeded 80 billion yuan in the first half of 2025, showing a year-on-year growth of over 60% [3][11] - Major provinces driving the procurement include Liaoning, Hainan, Ningxia, Fujian, and Shanxi, with imaging equipment being the core focus of upgrades [3][5] Summary by Sections Market Trends - The procurement scale for medical devices has remained high since 2025, with June procurement figures showing significant year-on-year increases across various categories, such as ultrasound (1.391 billion yuan, +49%), CT (1.938 billion yuan, +59%), and MRI (1.531 billion yuan, +64%) [4][12][15] - The bidding recovery is evident, with monthly procurement figures for 2025 showing consistent growth, despite a slight slowdown in June [3][11] Company Performance - Leading companies are expected to benefit significantly from the recovery in equipment bidding, with firms like Mindray Medical projecting a noticeable recovery in overall performance starting from Q3 2025 [3][5][21] - In June 2025, the bidding amounts for major domestic companies were as follows: Mindray (623 million yuan, +15%), United Imaging (769 million yuan, +35%), and Kaili Medical (102 million yuan, +73%) [4][18] Investment Recommendations - The report suggests focusing on domestic leading enterprises that are enhancing their high-end and intelligent medical equipment layouts, such as Mindray Medical, United Imaging, Kaili Medical, and Aohua Endoscopy [5][21] - The continuous support for equipment updates from government policies is expected to positively impact the industry, with a projected increase in procurement activities [21]

Investment Rating - The industry investment rating is "Outperform the Market" [2][45] Core Insights - The total bidding amount for medical devices in June 2025 reached 12.618 billion yuan, representing a year-on-year growth of 30% and a total of 83.817 billion yuan for the first half of 2025, with an overall year-on-year increase of 64% [3][9][10] Summary by Sections Medical Device Bidding Overview - The medical device bidding amount in June 2025 was 12.618 billion yuan, showing a year-on-year increase of 30% and a quarter-on-quarter decrease of 6% [9] - The cumulative bidding amount for the first half of 2025 was 83.817 billion yuan, with a year-on-year growth of 64% [10] Domestic Brands - Mindray Medical's bidding amount in June 2025 was 623 million yuan, up 15% year-on-year, with a total of 4.258 billion yuan for the first half of 2025, reflecting a 64% increase [16][18] - United Imaging's June 2025 bidding amount was 769 million yuan, a 35% year-on-year increase, totaling 4.841 billion yuan for the first half of 2025, up 53% [13][14] - Aohua Endoscopy's June 2025 bidding amount was 27 million yuan, down 46% year-on-year, with a total of 235 million yuan for the first half of 2025, up 57% [19][20] - Kaili Medical's June 2025 bidding amount was 102 million yuan, a 73% year-on-year increase, totaling 642 million yuan for the first half of 2025, up 115% [22][23] - Shanwaishan's June 2025 bidding amount was 30 million yuan, a 222% year-on-year increase, totaling 186 million yuan for the first half of 2025, up 211% [25][26] - Wandong Medical's June 2025 bidding amount was 222 million yuan, a 416% year-on-year increase, totaling 728 million yuan for the first half of 2025, up 107% [28][29] Imported Brands - Philips' June 2025 bidding amount was 658 million yuan, down 4% year-on-year, with a total of 4.570 billion yuan for the first half of 2025, up 61% [31][32] - Siemens' June 2025 bidding amount was 978 million yuan, a 48% year-on-year increase, totaling 6.074 billion yuan for the first half of 2025, up 60% [34][35] - GE's June 2025 bidding amount was 1.447 billion yuan, a 49% year-on-year increase, totaling 6.736 billion yuan for the first half of 2025, up 56% [37][38]

Investment Rating - The report maintains an "Outperform" rating for the pharmaceutical and biotechnology sector [5] Core Views - The pharmaceutical sector underperformed the overall market this week, with the healthcare services sector leading the gains. The overall A-share market rose by 1.50%, while the biopharmaceutical sector increased by 1.82%, outperforming the market [1][33] - Merck announced a $10 billion acquisition of Verona Pharma to obtain the COPD drug Ohtuvayre, which is expected to be a significant product in the respiratory disease treatment market [2][10] - WuXi AppTec is projected to achieve a 102% increase in net profit for the first half of 2025, with revenues expected to reach 20.799 billion yuan, reflecting a growth of 20.64% [3] Summary by Sections Market Performance - The biopharmaceutical sector's price-to-earnings ratio (TTM) stands at 35.79x, which is at the 77.7 percentile of its historical valuation over the past five years [1][38] - The overall A-share market and various sub-sectors showed positive performance, with healthcare services up by 6.46% [1][33] Key Company Updates - Merck's acquisition of Verona Pharma will provide access to Ohtuvayre, a dual-target PDE3/4 inhibitor approved for COPD maintenance therapy, marking a significant advancement in treatment options [2][10] - Ohtuvayre's sales reached $71 million in Q1 2025, indicating strong market uptake and potential for expansion into other indications [22][24] Company Earnings Forecasts - WuXi AppTec's net profit for H1 2025 is expected to be 8.561 billion yuan, a 101.92% increase, driven by strong operational performance [3] - The report includes earnings forecasts for several companies, with WuXi AppTec and Mindray Medical both rated as "Outperform" [4][42] Investment Recommendations - Mindray Medical is highlighted as a leading domestic medical device company benefiting from new healthcare infrastructure and product upgrades [42] - WuXi AppTec is recognized for its comprehensive service capabilities in the new drug development outsourcing market [42] - Other recommended companies include New Industries, Huatai Medical, and Aibo Medical, each with strong market positions and growth potential [42][43][44]

Group 1 - The core viewpoint of the article highlights the financial performance and market position of Kaili Medical, indicating a significant decline in revenue and profit in the latest quarterly report [1] - As of July 3, Kaili Medical's stock closed at 29.46 yuan, down 1.50%, with a rolling PE ratio of 253.53 times, and a total market capitalization of 12.748 billion yuan [1] - The average PE ratio for the medical device industry is 51.48 times, with a median of 36.88 times, positioning Kaili Medical at 119th in the industry ranking [1] Group 2 - Kaili Medical specializes in the research, development, production, and sales of medical diagnostic and treatment equipment, with key products including ultrasound diagnostic devices and minimally invasive surgical products [1] - The company has over 20 years of experience in the ultrasound industry and is recognized as a high-tech enterprise, holding leading core technologies in color Doppler ultrasound [1] - In the latest quarterly report for Q1 2025, Kaili Medical reported revenue of 430 million yuan, a year-on-year decrease of 10.29%, and a net profit of 8.0746 million yuan, down 91.94%, with a gross profit margin of 63.19% [1]

Group 1 - The core viewpoint of the articles highlights the financial performance and market position of Kaili Medical, indicating a significant decline in revenue and net profit in the first quarter of 2025 compared to the previous year [1][2] - As of July 1, 2023, Kaili Medical's stock price closed at 30.13 yuan, with a rolling PE ratio of 259.29 times, and a total market capitalization of 13.038 billion yuan [1] - The company operates in the medical device industry, which has an average PE ratio of 51.70 times and a median of 37.36 times, positioning Kaili Medical at the 119th rank within the industry [1][2] Group 2 - In the first quarter of 2025, the company reported an operating income of 430 million yuan, a year-on-year decrease of 10.29%, and a net profit of 8.0746 million yuan, reflecting a significant decline of 91.94% [2] - The company's gross profit margin stands at 63.19%, indicating a relatively high profitability despite the decline in revenue [2] - Kaili Medical specializes in the research, development, production, and sales of medical diagnostic and treatment equipment, with a strong focus on ultrasound diagnostic devices and other medical products [1]