Core Insights - Aethlon Medical has achieved a significant milestone by treating the second patient with the Hemopurifier in its clinical trial for solid tumors not responding to anti-PD-1 antibodies [1][2] - The trial aims to assess the safety and feasibility of the Hemopurifier, with the first cohort consisting of approximately 18 patients [6] - The Hemopurifier is designed to remove tumor-derived extracellular vesicles (EVs) from the bloodstream, potentially improving responses to anti-PD-1 therapies [5][7] Group 1: Clinical Trial Progress - The second patient was treated on June 11, 2025, at the Royal North Shore Hospital/University of Sydney, following the first patient treated on January 29, 2025 [1][2] - Both patients completed the 4-hour Hemopurifier treatment without device deficiencies or immediate complications, and have finished the 7-day safety follow-up period [2][4] - The Data Safety Monitoring Board (DSMB) will review the safety data after the third patient is enrolled, which is expected to occur soon [3][4] Group 2: Device and Mechanism - The Hemopurifier is an investigational device that utilizes plasma separation and affinity binding to remove enveloped viruses and EVs from circulation [7][8] - Preclinical studies indicate that the Hemopurifier can reduce the number of exosomes in cancer patient plasma, which may enhance the effectiveness of anti-PD-1 therapies [5][6] - The device holds FDA Breakthrough Device designation for treating advanced or metastatic cancer patients who are unresponsive to standard therapies [8] Group 3: Future Directions - The primary endpoint of the trial is to monitor adverse events and significant changes in safety lab tests among treated patients [6] - The study will also explore the number of Hemopurifier treatments required to decrease EV concentrations and whether this improves the immune response against tumor cells [6] - Data on the effects of the Hemopurifier on anti-tumor T cell activity is anticipated approximately three months after the enrollment of the third patient [3]

Exciting updates for the German Tesla SuperchargersTobi Mülhauser 🍕 (@TobiMuelhauser):Big news for the German Supercharger network 🚀⚡️Tesla has announced the launch of its first two Supercharger sites in collaboration with EDEKA. Both locations are open to all EVs and offer charging speeds of up to 250 kW 🔌📍 Locations:- Offenburg: 6 Superchargers at the new https://t.co/KiikUZcTg0 ...

Got your tickets yet? Tesla Summer Meetup in Muskegon Michigan! June 20th and 21st. Hosted by the @teslaownersmi Fun, Food and Fantastic EVs ! See you there! https://t.co/QSOMVeVU1A https://t.co/w4n5zli3Jm ...

Core Viewpoint - Tesla is facing significant challenges, including a decline in market share and a public feud between its CEO and the President of the United States, which may alienate customers [1][2]. Tesla's Market Position - Tesla has been losing market share in key global markets, particularly in the United States, despite price cuts on its best-selling electric vehicles [1]. - The company is still delivering close to 2 million cars globally each year, although this figure has started to decline [5]. Rivian's Current Situation - Rivian's stock has plummeted over 90% from its all-time highs, trading below $15, despite an initial public offering that raised over $10 billion and a market cap exceeding $100 billion [3][4]. - Rivian's deliveries have flattened out, with guidance for 40,000 to 46,000 deliveries in 2025, down from over 50,000 in 2024 [5]. Challenges for Rivian - High price points for Rivian's trucks and SUVs have limited its market share growth, as customers have shifted to more affordable options from legacy brands [6]. - Rivian is currently experiencing significant financial losses, with a $655 million operating loss reported in the first quarter of 2025 [9]. Future Growth Prospects for Rivian - Rivian plans to launch a more affordable EV, the R2, in 2026, priced around $45,000, which could expand its addressable market [8]. - The company has $8.5 billion in cash, a $3.5 billion commitment from Volkswagen, and a potential $6.6 billion loan from the Department of Energy, providing a runway for scaling manufacturing [11]. Investment Perspective - Rivian should not be viewed as a quick play on Tesla's market share losses; the automotive and EV sectors require time for trends to materialize [13]. - Rivian's current market cap is approximately $16.5 billion, with annual revenue around $5 billion, indicating long-term potential if the company successfully executes its growth plans [14].

以Mike Cikos为首的Needham分析师团队表示："GitLab公布了有史以来超出预期的幅度最小的财报，仅比营收指引的高端高出0.7%(过去4个季度的平 均水平为3.2%)。" Cikos补充道："管理层提到了SaaS产品组合规模扩大和线性化带来的不利影响。我们认为，颠覆的速度以及Cursor和Windsurf等竞争产品的涌现，正 在市场上制造噪音。" 尽管存在这些问题，Cikos仍然看好这家软件开发平台提供商。Cikos仍将GitLab与微软(MSFT.US)的Github视为两大领先的 DevSecOps平台。 CFRA维持对GitLab的"买入"评级，但将目标价从69美元下调至49美元。 CFRA分析师Janice Quek表示："虽然我们注意到该季度客户增长的放缓幅度超过预期，但我们也看到了一些积极因素，比如剩余履约价值(RPO)强 劲，反映出良好的交易势头和订单积压。GTLB提到了部分低端市场客户的成本敏感性，我们认为这可能是一个短期问题，与2025年4月的宏观经济 波动有关。" 智通财经APP获悉，软件开发商GitLab(GTLB.US)在公布略好于市场预期的第一季度业绩后，股价大幅下跌， ...

Financial Data and Key Metrics Changes - First quarter revenue increased by 27% year over year to $215 million, with a non-GAAP operating margin of 12% [5][24] - Non-GAAP gross margin was 90% for the quarter, with non-GAAP operating income of $26.1 million compared to a loss of $3.8 million in the same quarter last year [28][29] - Adjusted free cash flow reached $104.1 million, representing a record adjusted free cash flow margin of 49% [31] Business Line Data and Key Metrics Changes - The SaaS segment accounted for 30% of total revenue, growing 35% year over year [28] - The number of customers with ARR of at least $5,000 reached 10,104, contributing over 95% of total ARR [25] - The dollar-based net retention rate (DBNRR) was 122%, driven by seat expansion (80%), increased customer yield (5%), and tier upgrades (15%) [26][27] Market Data and Key Metrics Changes - Total remaining performance obligations (RPO) grew by 40% year over year to $955.1 million, while current RPO (CRPO) grew by 34% year over year to $584.8 million [27] - The larger customer cohort of $100,000+ in ARR increased by 26% year over year, reaching 1,288 [25] Company Strategy and Development Direction - The company positions itself as the only AI-native, cloud-agnostic, model-neutral DevSecOps platform, emphasizing its unique capabilities in the software development lifecycle [6][7] - GitLab aims to enhance its AI capabilities and integrate them throughout the platform, focusing on security and compliance as key drivers for adoption [10][22] - The company is expanding its market presence through partnerships, such as with AWS, to enhance customer engagement and showcase its solutions [13][22] Management's Comments on Operating Environment and Future Outlook - Management expressed confidence in the company's ability to generate sustainable growth and enhance profitability despite evolving market conditions [24][30] - The outlook for the second quarter expects total revenue of $226 million to $227 million, representing a growth rate of approximately 24% year over year [30] - Management noted that the macroeconomic environment remains cautious, but demand for the platform continues to be strong [104] Other Important Information - GitLab achieved FedRAMP moderate authorization for its dedicated SaaS solution, which is expected to boost its public sector business [19] - The company is on track to launch GitLab Duo Workflow, an AI solution, in the upcoming months [13][33] Q&A Session Summary Question: Customer Conversations on AI - Management noted that AI is a central topic in customer discussions, with teams looking to leverage AI for productivity and innovation [38] Question: Growth Metrics and Deal Linearity - Management confirmed that the quarter's performance was consistent with expectations, with a mix favoring SaaS and back-end weighted linearity [44][45] Question: Customer Additions and Pricing Changes - Management indicated that while there was a deceleration in new customer additions, it did not impact financials significantly [49][51] Question: AI's Impact on Developer Job Growth - Management believes that AI will increase the number of code creators and overall code volume, benefiting GitLab's business model [60][61] Question: Enhancements with GitLab 18 - Management highlighted the focus on creating value through AI integration and enhancing collaboration between humans and agents [68][70]

India SMID Portfolio Sona Blw Precision Forgings Ltd Rating Market-Perform (Outperform OLD) Price Target SONACOMS.IN 540.00 INR (550.00 OLD) 10 June 2025 Rating Change Venugopal Garre +65 6326 7643 venugopal.garre@bernsteinsg.com Ankit Agrawal, CFA +91 226 842 1441 ankit.agrawal@bernsteinsg.com Sona BLW: EV risks increasing-Downgrade to Market-Perform We are downgrading Sona BLW to Market-Perform. Trump–Elon tensions, the proposed "big, beautiful" bill phasing out EV subsidies, ongoing US–India trade issues ...

With this week comes the official close of first-quarter earnings season in Needham analyst Mike Cikos‘ coverage, in which Cognyte Software CGNT and GitLab Inc GTLB are the final two companies reporting.Cikos maintained Buy on GitLab with a price target of $85 and noted shares are due for a rebound given his expectation for sustained execution. He had a Hold rating on Cognyte.The analyst noted both companies are likely to report upside, resulting in outsized positive share-price performance.Cognyte: Cikos n ...

Key Takeaways GTLB expects Q1 fiscal 2026 revenues of $212M-$213M, up 25-26% year over year. Investments in AI, GitLab Duo, and GitLab Dedicated likely supported customer growth and adoption. Expanding use by Delta, NatWest, and Amazon may have driven recurring revenues and platform momentum.GitLab (GTLB) is set to release its first-quarter fiscal 2026 results on June 10, 2025.The company expects first-quarter fiscal 2026 revenues between $212 million and $213 million, indicating 25-26% year-over-year gro ...

Core Insights - JFrog (NASDAQ: FROG) is identified as a high growth tech stock that has faced significant volatility in the current year [1] Company Overview - JFrog operates as a DevSecOps software platform, assisting other technology companies in their software development processes [1] Analyst Background - Gary Alexander, with extensive experience in covering technology companies and advising startups, contributes insights on industry trends and has been active on Seeking Alpha since 2017 [1]