Core Insights - Chronic non-communicable diseases such as cardiovascular diseases, diabetes, and respiratory diseases are the leading causes of death in China, with a significant portion of deaths attributed to these conditions [1] - The management of hypertension, hyperglycemia, and hyperlipidemia (the "three highs") is crucial for reducing cardiovascular events, as these conditions are interlinked and pose a high risk for heart failure [1] - There is a pressing need for integrated management of chronic diseases to improve overall patient health and reduce hospitalization and mortality rates [1] Group 1: Cardiovascular and Chronic Diseases - Over 29% of patients have two or more risk factors related to the "three highs," significantly increasing the risk of severe cardiovascular events [1] - Chronic heart failure is a major cause of death from cardiovascular diseases, necessitating strict adherence to management guidelines to mitigate risks [1] - The overlap between chronic heart failure and chronic obstructive pulmonary disease (COPD) complicates patient management and increases hospitalization and mortality risks [2] Group 2: Diabetes and Kidney Disease - More than 40% of chronic kidney disease patients have underlying conditions such as diabetes and hypertension, highlighting the interrelated nature of these diseases [2] - Approximately 80% of diabetes patients die from cardiovascular events, and 20%-40% may develop diabetic nephropathy, indicating the need for comprehensive management strategies [2] - Regular monitoring of kidney function through tests like UACR and serum creatinine is essential for high-risk groups, including those with diabetes and cardiovascular diseases [2] Group 3: Treatment Challenges and Innovations - Current treatment methods for hypertension are inadequate in controlling elevated aldosterone levels, which are a key factor in poor blood pressure management [2] - There is a need for innovative treatment options to address the challenges posed by chronic diseases and their complications [2] - Early identification and diagnosis of conditions like transthyretin amyloid cardiomyopathy are critical for improving patient outcomes and prolonging survival [3]

Core Insights - The number of cardiovascular disease patients in China has reached 330 million, with hypertension patients at 245 million, and deaths from cardiovascular diseases account for nearly 50% of total deaths, making it the leading health threat [1][3] Group 1: Current Situation and Challenges - Cardiovascular disease prevention and treatment have been prioritized under the "Healthy China 2030" strategy, showing significant progress, yet the overall prevention situation remains severe due to an aging population and the high number of patients [1][7] - The prevalence rates of hypertension, diabetes, and dyslipidemia among adults in China are 27.9%, 11.2%, and 40.4% respectively, with each condition affecting over 100 million individuals [3][8] - The burden of cardiovascular diseases is compounded by the presence of multiple comorbidities, which can lead to increased health risks and resource consumption [2][5] Group 2: Comorbidities and Their Impact - Patients with cardiovascular diseases often face complex medication regimens and treatment burdens, which can lead to repeated health crises and decreased quality of life [2][4] - Infections, particularly herpes zoster, pose significant risks to cardiovascular patients, potentially leading to severe complications such as heart failure and stroke [2][3] - The incidence of herpes zoster is notably higher in older adults and those with chronic diseases, with cardiovascular patients being 39% more likely to contract it compared to the general population [5][8] Group 3: Prevention and Management Strategies - The "Health China Action" emphasizes a comprehensive management approach for cardiovascular diseases, focusing on prevention and early intervention [7][9] - Vaccination against herpes zoster is recommended for high-risk groups, including older adults and those with cardiovascular conditions, to reduce the incidence and severity of related complications [6][8] - Community health services play a crucial role in preventive care, providing education and vaccination services to manage chronic diseases effectively [9]