Core Viewpoint - The company reported a significant decline in revenue and profit for the first half of 2025, primarily due to the inclusion of key products in centralized procurement, but it remains optimistic about future growth through innovation and international collaboration [1][2][3]. Financial Performance - Total revenue for the first half of 2025 was 13.273 billion RMB, a decrease of 18.5% year-on-year - Profit attributable to shareholders was 2.548 billion RMB, down 15.64% year-on-year - Basic earnings per share were 0.2229 RMB, with an interim dividend proposed at 0.14 HKD per share [1]. Research and Development - R&D expenses increased by 5.5% year-on-year to 2.683 billion RMB, accounting for 26.2% of the revenue from the pharmaceutical business - The company has nearly 90 products in various stages of clinical trials, with 12 submitted for market approval and over 30 key products in the registration clinical phase [1][4]. Strategic Initiatives - The company is focusing on a "dual-driven" strategy of "innovation + internationalization," enhancing partnerships with global pharmaceutical firms through diverse models such as licensing and collaborative R&D - In the first half of 2025, licensing revenue reached 1.075 billion RMB, indicating strong recognition of the company's innovative pipeline in the international pharmaceutical industry [2][3]. Global Expansion - The company is advancing its global strategy by establishing a comprehensive pharmaceutical value ecosystem and conducting multiple multi-center clinical trials in Europe and the U.S. - It has completed four licensing projects this year, with a cumulative contract amount of 9.71 billion USD, and has entered a strategic R&D collaboration with AstraZeneca [3][4]. Innovation Pipeline - The company has been recognized as one of the top 25 pharmaceutical companies globally by Citeline for three consecutive years, ranking 19th this year, an improvement of five places from the previous year - It has over 200 innovative drugs and formulations in development, with more than 160 clinical trials ongoing, including nearly 60 in Phase III [4].

Group 1: Financial Performance - The company reported total revenue of 13.273 billion RMB, a year-on-year decrease of 18.5% [1] - Profit attributable to shareholders was 2.548 billion RMB, down 15.64% year-on-year, with basic earnings per share at 22.29 cents [1] - The gross profit margin decreased by 6.0 percentage points to 65.6%, primarily due to a reduction in the revenue share from the prescription drug business [1] Group 2: Research and Development - R&D expenses increased by 5.5% year-on-year to 2.683 billion RMB, accounting for 26.2% of prescription drug revenue [1] - The company has nearly 90 products in various stages of clinical trials, with 12 submitted for market approval and over 30 key products in the registration clinical phase [1] - The company focuses on high-demand treatment areas such as breast cancer and lung cancer, accelerating the commercialization of core products [2] Group 3: Strategic Initiatives - The company is implementing a "dual-driven" strategy of "innovation + internationalization," enhancing cooperation with global innovative pharmaceutical companies [2] - Authorization revenue reached 1.075 billion RMB in the first half of 2025, providing new growth momentum for the prescription drug business [2] - The company has completed four external authorization projects with a cumulative contract amount of 9.71 billion USD [3] Group 4: Global Expansion and Recognition - The company has been recognized as a "national-level innovative enterprise" and has established key national laboratories [4] - It ranks 19th in the global TOP25 pipeline scale pharmaceutical companies, improving its position by 5 places compared to the previous year [4] - The company is expected to submit over 50 new drugs or new indications for approval by the end of 2028 [4]