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华人学者本周发表4篇Cell论文:玫瑰花香调控基因的从头诞生、肿瘤劫持巨噬细胞以促进骨转移和贫血、破译乳腺癌起源和进展...
生物世界· 2025-09-07 09:00
Group 1 - The article highlights seven research papers published in the prestigious journal Cell during the week of September 1 to September 7, 2025, with four of them authored by Chinese scholars [3] - The first study discusses a newly discovered gene SCREP that drives the diversification of rose scent, revealing a multi-step process of its origin and its role in inhibiting the synthesis of the key aromatic compound eugenol [5][8] - The second study presents a breakthrough in the reprogramming of microspore fate, establishing a new technique for efficient in vivo haploid induction without stress treatment, highlighting the roles of the transcription factors BBM and BAR1 [10][12][13] Group 2 - The third study uncovers how cancer cells hijack iron-rich macrophages to promote bone metastasis and anemia, providing insights into potential therapies to mitigate these conditions [15][18] - The fourth study introduces a high-throughput, high-precision single-cell DNA and RNA multi-omics technology called wellDR-seq, which decodes the mechanisms of breast cancer progression by integrating single-cell genomes and transcriptomes [20][23]
华中农业大学发表最新Cell论文
生物世界· 2025-09-03 00:15
撰文丨王聪 编辑丨王多鱼 排版丨水成文 基因的出现归因于多种过程,包括基因复制 - 趋异、转座元件驯化、水平基因转移、基因融合与分裂以及从非编码序列中从头起源。尽管从头起源曾被视为罕见 现象,但新出现的证据表明其发生频率相当高。然而,仅有少数研究报道了通过多个进化步骤从零开始构建基因的情况。此外,对于这些新形成的基因如何实现 增强表达并融入现有的基因调控网络从而影响表型进化,我们的理解仍然有限。 | 2025 年 | 9 月 | 2 日, | 华中农业大学 | | 宁国贵 | 教授团队 | ( | | | | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | | 李亚军 | | 、 | | 李润慧 | 、 尚均忠 | | 、 | 赵凯歌 | | | 为共同第一作者 | | | | ) | 在国际顶尖学术期刊 | Cell | 上发表了题 | | | | 为: | | A | | de novo | | -originated gene drives rose scent diversification | | | 的研究论 | | 文。 | ...