星形胶质细胞

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啊?猫猫也会老年痴呆
量子位· 2025-08-28 07:29
Core Viewpoint - Recent research indicates that elderly cats can develop dementia-like symptoms similar to human Alzheimer's disease, with the accumulation of amyloid beta plaques in their brains [2][6][21]. Group 1: Research Findings - A study published in the European Journal of Neuroscience found that elderly cats exhibit amyloid beta accumulation in their brains, which may lead to dementia-like behaviors [2][4]. - The research team analyzed the brains of 25 cats, including 18 elderly cats, and found that all elderly cats had higher levels of amyloid beta compared to younger cats [7][9]. - The study revealed that both microglia and astrocytes, immune cells in the brain, were overactive in elderly cats, indicating a response to the presence of amyloid beta plaques [13][19]. Group 2: Implications for Alzheimer's Research - The similarities in brain pathology between cats with cognitive dysfunction syndrome (CDS) and human Alzheimer's disease suggest that cats could serve as a natural model for studying Alzheimer's [21][24]. - The findings support the idea that CDS in cats may provide insights into the mechanisms of Alzheimer's disease and potential therapeutic targets [25][28]. - Future research aims to explore additional Alzheimer's-related biomarkers, such as tau protein accumulation, in cats [27].