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悦康药业构建mRNA技术生态,加速生物医药创新步伐
Quan Jing Wang· 2025-04-29 10:27
Core Insights - Recently, Yuyuan Pharmaceutical achieved a breakthrough in new drug development with its mRNA vaccine YKYY025 for respiratory syncytial virus (RSV) receiving clinical trial approval from the National Medical Products Administration (NMPA) in China, following prior approval from the FDA in the United States, showcasing the company's strong innovation capabilities and international competitiveness [1][3] Group 1: Innovation in mRNA Vaccine Development - Yuyuan Pharmaceutical's subsidiary, Hangzhou Tianlong Pharmaceutical, has successfully submitted clinical trial applications for multiple mRNA vaccines, including YKYY026 for shingles, which has also been accepted by the NMPA [3] - The company has received clinical approvals for its broad-spectrum anti-coronavirus peptide YKYY017 aerosol inhalation and long-acting lipid-lowering nucleic acid drug YKYY015 in both China and the U.S. [3] - Yuyuan's proprietary nucleic acid delivery system has been granted patents in multiple countries, including the U.S., Japan, and Israel, establishing a solid foundation for its mRNA vaccine and nucleic acid drug development [3] Group 2: Comprehensive R&D Platform - The company has built a complete platform system for nucleic acid drug development, covering target discovery, high-throughput screening, process development, and quality control, which is rare among domestic pharmaceutical companies [4] - Yuyuan Pharmaceutical has multiple innovative products nearing commercialization, with three class 1 innovative drugs receiving acceptance for market application, and its peptide drug YKYY017 entering phase III clinical trials [4] - The anti-liver cancer antisense oligonucleotide drug CT102 has completed phase IIa clinical trials, indicating a strong pipeline that could provide new treatment options for patients and drive future growth for the company [4]